Protein Alignment Clc and Clta

DIOPT Version :9

• Sequence 1: NP_001163480.1
• Gene: Clc / 40221
• FlyBaseID: FBgn0024814
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_001073854.1
• Gene: Clta / 12757
• MGIID: 894297
• Length: 248
• Species: Mus musculus
• Alignment Length: 247
• Identity: 87/247 - (35%)
• Similarity: 120/247 - (48%)
• Gaps: 57/247 - (23%)

  Fly     4 GDDFAAKEDVDPAAEFLAREQSALGDLEAEITGGSASAPPAASTDEGLGELLGGTASEGDLLSAG 68
            |:..|...:.||||.|||:::|.:..:|               .||....|.||  :.|......
Mouse    20 GNGVAGAGEEDPAAAFLAQQESEIAGIE---------------NDEAFAILDGG--APGPQPHGE 67

  Fly    69 GTGGLESSTGSFEVIGG----ESNEP----VGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEE 125
            ..||.::..|   |:.|    |||.|    ..||.....:.|||.||||||||.:|||..|....
Mouse    68 PPGGPDAVDG---VMNGEYYQESNGPTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSR 129

  Fly   126 RKKEELRQQSKKELDDWLRQIGESISKTKLASRNAE----KQ---------------AATLENGT 171
            :::.|.::::.|||::|..:..|.:.|||..:|.|:    ||               ..:||...
Mouse   130 KQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVTNINHPCYSLEQAA 194

  Fly   172 IE----------PGTEWERIAKLCDFNPKVNKAGKDVSRMRSIYLHLKQNPI 213
            .|          |||||||:|:|||||||.:|..||||||||:.:.|||.|:
Mouse   195 EEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clc	NP_001163480.1	Clathrin_lg_ch	6..212	CDD:279433	85/242 (35%)
Clta	NP_001073854.1	Clathrin_lg_ch	20..243	CDD:366457	84/242 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845961
Domainoid	1	1.000	133	1.000	Domainoid score	I5044
eggNOG	1	0.900	-	-		E1_KOG4031
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1384
Inparanoid	1	1.050	134	1.000	Inparanoid score	I4563
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46883
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002725
OrthoInspector	1	1.000	-	-		otm42898
orthoMCL	1	0.900	-	-		OOG6_103026
Panther	1	1.100	-	-	O	PTHR10639
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R206
SonicParanoid	1	1.000	-	-		X3012
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790