Protein Alignment CG17233 and Prr12

DIOPT Version :10

• Sequence 1: NP_730500.1
• Gene: CG17233 / 40220
• FlyBaseID: FBgn0036958
• Length: 1465
• Species: Drosophila melanogaster
• Sequence 2: NP_001414781.1
• Gene: Prr12 / 361569
• RGDID: 1309896
• Length: 2032
• Species: Rattus norvegicus
• Alignment Length: 1889
• Identity: 302/1889 - (15%)
• Similarity: 509/1889 - (26%)
• Gaps: 768/1889 - (40%)

  Fly    21 GSSGGTAEDF-QHPHLATITAASIASFNAAAASGGSFVPPS---PIG-----SYNP--VFQQIY- 73
            |..||.|:|. :.|:.                |||...|||   |.|     ||:|  :..|:|
  Rat   457 GFGGGQAQDLSKGPNY----------------SGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYG 505

  Fly    74 -----HHAAAASVQPKPAHYASSAVSTPH----------------------------RQLQLPSS 105
                 :...||..|..|....|.:.||.|                            |.||.|.:
  Rat   506 VQSEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPA 570

  Fly   106 L------------DKQLSS------FQNQAAVSAAAAAVVNNVASNYYGENSSS------SGA-- 144
            .            .|.|||      |......|:.||.     |..|.|:...|      .||
  Rat   571 TGRPPGVGSPGAPGKYLSSVLASAPFLAPPGASSYAAG-----AGGYKGKGDGSELLAGPGGAAA 630

  Fly   145 ---------------SPSPTTVALTSTSLTWNTPNMISNTF---------------LAMQQQQAQ 179
                           :|||...:.....:..:.|...|...               ||.:..| :
  Rat   631 ERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGPADASKGLGGSGGAGGPPGTPYELAKEDPQ-R 694

  Fly   180 QQQQQAQQQQQQAQQQQQQAQQQQLNLVADKVQIKQE-------------------KQLKAYNDS 225
            ...|...:......:....|.:..|..:.||.:..:.                   |:|.|:
  Rat   695 YHLQSVIRTSASLDEGATAALELGLGRMKDKKKGPERGGETPEGLATSVVHYGAGAKELGAF--- 756

  Fly   226 IYLIQLQQQQQQQQTAAQQQQQQLH--------------------QQLQQEIAEADTEPDTYYTI 270
                 ||:........||..|...|                    |.|...::.|.:...:...:
  Rat   757 -----LQKSPPPPPPTAQATQPTPHGLLLEAGGPDLPMVLPPPPPQLLPSVLSHAPSPSSSAPKV 816

  Fly   271 DGRKVKVTRKDGQPYRATIVDQQDASPVPLAVPVPAGSYPVQYAS--------PALSSADGSPIT 327
            ....::...:||.|           .|.|   |.|....|:|..:        |.      :|..
  Rat   817 GVHLLEPGTRDGAP-----------QPPP---PPPPPPMPLQLEAHLRGHGLEPT------APSP 861

  Fly   328 NLHAVDVVSTPQAQVIVYKTASPV--------------QRRQEAGAGSS----AAATPTTVAYSS 374
            .|...:.:..|.|...:.....|:              :.:...||..|    ....|..|..:|
  Rat   862 RLRPEESLEPPGAMQELLGALEPLPPGPGDTGVGPPNPEGKDPTGAYRSPSPQGTKAPRFVPLTS 926

  Fly   375 VIQSTLQQQQQQQNLCWTKLEDNGAGQEDIKNVLQLQVKQEHRQLDFASEASSVDAG-------- 431
            :.......|.::::...|..|..|.|..|                |:.....:.|.|
  Rat   927 ICFPDSLLQDEERSFFPTMEEMFGGGAAD----------------DYGKAGQTEDDGDPKTGAGP 975

  Fly   432 --------------GG----------GENLVFNLPPGLEIKQTFYPASVVDGEQLQLQEHNQNQS 472
                          ||          |..|..|.||.|        .|.|:.|.|.|.:...:||
  Rat   976 PPGPTAYDPYGPYCGGRASGTGPETPGLGLDPNKPPEL--------PSTVNAEPLGLIQSGPHQS 1032

  Fly   473 QSSGRRQHVVANMIMSPSAGNLASQIQVVPKEEVKPPPKPAKTPR---------KRQPKKTLIPS 528
                           :|            |.....|||.|...|:         ..:|||.|..|
  Rat  1033 ---------------AP------------PPPPPPPPPPPVSEPKGGLTSPIFCSTKPKKLLKTS 1070

  Fly   529 SSDYGNVRSPQEPQHHQLQQQQQQQQQHNQQQQQQNTYYDFNS---KWNAPLKTENN-------- 582
            |             .|.|:::....|...:...|:   |:|.:   |.:.|.....|
  Rat  1071 S-------------FHLLRRRDPPFQTPKKLYAQE---YEFEADEDKADVPADIRLNPRRLPDLV 1119

  Fly   583 -----AASVSPAATINI------PTYPQQSQQQQHQQQQAQQQQQQHLPQPAHLQSSQAQSHLTQ 636
                 ..::||...|:.      |..|::..::..:.::....:.:..|:...|:.
  Rat  1120 SSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEG--------- 1175

  Fly   637 LAQYYPAFPQPIASQYTACMQQQQQQQQQQQQQQQQQAAYTQQQHQQAYTQQQQQQAQQQRQEKS 701
                 ||...|.::..|....::.:.:.:.:.::.::...|                      :.
  Rat  1176 -----PAMAGPASASITTDGAKKPRGRGRGRGRKAEEMGGT----------------------RL 1213

  Fly   702 EATQQQEEEANAAAAAAAAAAASNKVI--------------------VPNIEEE----------- 735
            |..:..:.:.:.........|.||.||                    :..:||:
  Rat  1214 EPLKPLKIKLSVPKVGEGLGAPSNDVISGVDHNSLDSNLTREKIEAKIKEVEEKQPEMKSGFMAS 1278

  Fly   736 -LDFLADATATP---KQGYANSLSSNGRGTNSSTNNTNFGIRNPNKTPSPEPTN--CPPNSHASN 794
             ||||......|   :.|....||.                  |...|:..||.  .||......
  Rat  1279 FLDFLKSGKRHPPVYQAGLTPPLSP------------------PKSVPASVPTRGLQPPPPTVPT 1325

  Fly   795 NGHGHSAVTPVAPSSTGASASTAYSP----VAPKPVSVGTLIGEKKTQFMDSYLKFLQGERDD-- 853
            ..|    ..|..|...|.:...|.|.    ..|.|..   .:.|:..:.:::...|...|.|.
  Rat  1326 VPH----PAPSGPFGLGGALEAAESEGLGLGCPSPCK---RLDEELKRNLETLPSFSSDEEDSVA 1383

  Fly   854 ----------------DPPPVVKPSRKLNYPRAPYKRKGKGSGSGDEPTTS-QATQSAGDAVQAV 901
                            |.||:..| :..:.|..|....|. :.||..|..| .:|.|.|..
  Rat  1384 KNRDLQESISSAISALDDPPLTGP-KDTSTPEEPPLDTGP-TASGPPPLPSLPSTNSNGTP---- 1442

  Fly   902 DGLAGLVGDDGHRIKILSQ----------------------TQILPKKRPHAQMVAAAAAAESAP 944
                        ...:|.:                      ...||...|....||::......|
  Rat  1443 ------------EPPLLEEKPPPTPPPAPTPQPAPPPPPPPVPALPSPAPLVTPVASSPPPPQPP 1495

  Fly   945 SSSVIQQPGD-----QTSFRPYAQQQQQAQQQQQQSMSGQHFVQQHCAQLTAGAGQDPLSVPPRR 1004
            ....:..|..     .|:..|.|..::.|                      |.:.:||.....|.
  Rat  1496 PPPALPSPPPPPPPAPTTVPPVAPPEEPA----------------------APSPEDPEPPDARP 1538

  Fly  1005 EQCSRKAKQSSMHAMLMNSSSVVGDGGVVGEPDEF---------------TDSDTDPVW------ 1048
            ...::|.:.:::.......:...|..|:..|.|||               |..:..|:|
  Rat  1539 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKAL 1603

  Fly  1049 ----TPQEEDSD--------------DGKG-----YGK-----------RKLARR---------- 1069
                ||:.:|..              |.|.     |.|           |..||:
  Rat  1604 LQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPLPVR 1668

  Fly  1070 ----SKG----------------------TPRKNTYDHSSGLQQQPQQQQQHHQQLQQMQVNQQH 1108
                :||                      ||.|.|.:.......:|...:....:........:.
  Rat  1669 RSGQTKGPTPVGGNAAPPSKVPAPPPKPETPEKMTSEKPPEPTPEPAVPEPPAPEKPSPPRPAEK 1733

  Fly  1109 HQQQQQVQQMAGGESTYNSQQNMSG---------------------------------------- 1133
            .:::::.:...||:....|::..||
  Rat  1734 EKEKEKERVTRGGDRPLRSERAASGRQMRTDRSLAPGQSTTSRLPKARPSKVKAEPPPKKRKKWL 1798

  Fly  1134 VADVGYASASSGPAANSENFKTGDFIVLRSDLVNDWPTIWQVDSKCILQKYEPFRQNGKTFYRNM 1198
            ...||.|||..||..:|.:.::.             |.....|.:.:     |.|.
  Rat  1799 KEAVGSASAGDGPGCSSSDSESS-------------PGAPSEDERAV-----PGRL--------- 1836

  Fly  1199 SKYASWNLETKKLYLKAPVRIQLHSHTETIVEFMRSELLADDTEQFIEKIMEDYLSYRDNFEIYI 1263
                   |:|:.:                                            |:.:..|:
  Rat  1837 -------LKTRAM--------------------------------------------REMYRSYV 1850

  Fly  1264 QTMISQALDPSFFSEITREKDDYFLGSVRVVDNIMENCKRKLLAITPWTRSTISSIETWPKCHVF 1328
            :.::|.||||.....:....|:.:|..:|.:|.::...|:|:|.....:.:...::.|:|:..|
  Rat  1851 EMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQV- 1914

  Fly  1329 SEWEQNNLTQKNCAGCHQPGIAVRFLLFGEPYNPNTMQTIPVDPRIVYEKDIVLCRICAARAD-- 1391
               ||..      .|..:.| |||....|||||..|:..:        ::.:|..:......:
  Rat  1915 ---EQTG------EGSPEEG-AVRLRPAGEPYNRKTLSKL--------KRSVVRAQEFKVELEKS 1961

  Fly  1392 ----LFHKIAHEKFNLFINCSQRVTEQQQQFPGKTSTEILNDLLAEHNWIDELFRNMRNCWAEVE 1452
                |:|.:.|.|::.|:.|..:....:.........|::...:....|:::||.:..:..|:.:
  Rat  1962 GYYTLYHSLHHYKYHTFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQ 2026

  Fly  1453 SLER 1456
            :..|
  Rat  2027 AHSR 2030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17233	NP_730500.1	DUF4211	1228..1365	CDD:464045	29/136 (21%)
Prr12	NP_001414781.1	None