Protein Alignment CG17233 and Qser1

DIOPT Version :10

• Sequence 1: NP_730500.1
• Gene: CG17233 / 40220
• FlyBaseID: FBgn0036958
• Length: 1465
• Species: Drosophila melanogaster
• Sequence 2: XP_038960857.1
• Gene: Qser1 / 311266
• RGDID: 1311804
• Length: 1752
• Species: Rattus norvegicus
• Alignment Length: 1891
• Identity: 354/1891 - (18%)
• Similarity: 598/1891 - (31%)
• Gaps: 636/1891 - (33%)

  Fly     3 PNSSPWSYAYNRIVPASA------GSSGGTAEDFQ--HP---------------------HLATI 38
            |.:..|  ||...|||:|      |||......::  ||                     :.||.
  Rat    24 PAAPAW--AYEARVPAAASSPSCSGSSPSLKASYEDVHPSQSESDVLQRQTFTASHQLPGYAATP 86

  Fly    39 TAASIASFNAAAASGGSFVPPSPIGSYNPVFQQIYHHAAAAS-----------VQPKPAHYASSA 92
            .|..:.|..||.......:|.|  |:..|.....|.|.|:.|           :|....:..|:.
  Rat    87 QATGMHSSTAAELFVTGPLPTS--GTLPPPTLSAYQHPASFSNRNFVTTSPLVLQDSSFNTTSNG 149

  Fly    93 VSTPHRQLQLPSSLDKQLSSFQNQAAVSAAAAAVVNNVASNYYGENSSSSGASPSPTTVALTSTS 157
            :..||         |..|....:|..|..|.|.           |...||..|.|....:.|..|
  Rat   150 ILNPH---------DPLLQIKTSQGTVPTALAF-----------ERLGSSALSNSIPPQSSTYRS 194

  Fly   158 LTWNTPNMISNTFLAMQQ-----QQAQQQQQQAQQQQQQAQQQQQQAQQ------QQLNLVADKV 211
            ...:.|:::...|..:..     ||..|....|......|..::...::      .|...|...:
  Rat   195 AQESAPHLLQPQFSLLPSTLGGAQQTPQAYSSALFTNSAASIERALLRECSVIKHHQRPSVTQSI 259

  Fly   212 QIK---QEKQLKAYNDSIYLIQLQQQQQQQQ---TAAQQQQQQLHQQLQQEIAEADTE-PDTYYT 269
            |.:   .:..|.:|..|..:...|:..:|..   ::.:...|..:..|||:..:...| ..:|.:
  Rat   260 QAQLTGSQHPLHSYLSSASIGSFQETSRQSSLSCSSVRDSTQVSNGVLQQKTPQVSAELAQSYSS 324

  Fly   270 I---DGRKVKVTRKDG----QPYRATIVDQQDASPVPLAVPVPAGSYPVQ---YASPALSSADGS 324
            :   .|.....|:.|.    ||..:|.:      |.|.:| :|    |||   |:.|
  Rat   325 VIPSSGYLPSATKVDSCSTKQPLTSTTI------PKPQSV-IP----PVQTLNYSKP-------- 370

  Fly   325 PITNLHAVDVVSTPQAQVIVYKTAS-----PVQRRQEAGAGSSAAATPTTVAYSSVIQSTLQQQQ 384
                ||....|.:.|||  :|.||.     .|.:.|..|     :..|..|  .|::.|.:.:..
  Rat   371 ----LHNQSSVISGQAQ--IYSTAQLPSLLSVSQSQNYG-----SVQPHGV--PSIVHSQVYRSS 422

  Fly   385 QQQNL--CWTKLEDNGAGQEDIKNVLQLQVKQEHRQLDFASEASSVDAGGGGENLVFNLPPGLEI 447
            :.:.|  .:..|...|:.|         .|..|::.|.::|....|.:....||
  Rat   423 RAEKLPPLYKTLTFPGSSQ---------PVTSENQTLSYSSNQQEVLSLVTNEN----------- 467

  Fly   448 KQTFYPASVVDGEQLQLQEHNQNQSQSSGRRQHVVANMIMSPSAGNLASQIQVV----PKEE--- 505
                |||...|     |...:::|:.|||..|.:..   :|.:..:.:||.||:    |.|.
  Rat   468 ----YPAQTRD-----LSSVSESQNYSSGHSQGLSP---VSQTQVSYSSQSQVLSVVSPSESYAS 520

  Fly   506 ----VKPPPK------------PAKTPRKRQPKKTLIPSSSDYGNVRSPQEPQHHQLQQQQQQQQ 554
                ..|.|.            |..||....|.....|::...|:  ||.:||.. |...|....
  Rat   521 GQSLTLPAPSLSYSSASRGQSLPVSTPTPNYPSMHSSPNAQTQGS--SPPQPQKF-LPVVQSSFA 582

  Fly   555 QHNQQQQQQNTYYDFNSKWNAPLKTENNAASVSPAATINIPTYPQQSQQQQHQQQQAQQQQQQHL 619
            ..::.|..|::....:||..|..|.::|..:.|..     ..:|.| :.|..|.|.:.:...|.|
  Rat   583 SSSRGQTLQSSIASPDSKSYAERKLDSNVYTSSKQ-----DDFPMQ-KLQALQSQASLESSSQRL 641

  Fly   620 P--------------------------QPAHLQ----------SSQAQSHLTQLAQYYPAFPQPI 648
            |                          ..:||:          |.|.::.:..:........||.
  Rat   642 PDGEVNAQESVYKTSKADDRYSQSVTRNNSHLEDQVVGVGLQGSKQEENMVGSMTPLNQQSSQPN 706

  Fly   649 AS------QYTACMQQQQ------QQQQQQQQQQQQQAAYTQQQHQQAYTQQQQQQAQQQRQEKS 701
            .|      :.|..||..|      ...||.....:...|..||||.|..:...|.|........|
  Rat   707 TSVAPDLKKSTNLMQTPQIRLNTKDLTQQHSLMHKMHGAKAQQQHDQMISATPQIQVPNHALGHS 771

  Fly   702 EAT-------------QQQEEEANAAAAAAAAAAASNKVIVPNIEEELDFLADATATPKQGYANS 753
            ...             .|..::|....|:...|.||.:|             ....:|:|.....
  Rat   772 HQALPNAPVLADSACHLQILQQAGMLQASLGQAKASLQV-------------QRVQSPQQIVHPF 823

  Fly   754 LSSNGR--GTNSSTNNTNFGIRNPN--KTPSPEP-------TNCPPNSHASNNGHGH-------- 799
            |..:|.  .:|..........:||:  |...|||       |..|.:|.:.....|.
  Rat   824 LQMDGHIIQSNGEHPQQQLHAQNPDVMKLDLPEPSKPLQQLTTNPQDSKSQFVSLGSICFPEAML 888

  Fly   800 ------------------SAVTPVAPSSTGASAS-----------------------------TA 817
                              :|...|.||....||:                             .:
  Rat   889 LSDERNILSNVDDILAATAAACGVTPSEFSKSAANETMQDIESSDSKPHYQQSLDVRHVNSDFNS 953

  Fly   818 YSPVAPKPVSVG--TLIGEKKTQFMDSYLKFLQGERDDDPPPVVKPSRKLNYP-RAPYKRKGKG- 878
            .:....||.|:.  :|.|.:.:..:.| :..||.|...|.|.:...|:  |.| :.|....|.|
  Rat   954 ITATVGKPQSINDISLNGNQVSVNLSS-VPTLQSETVLDQPHMETSSQ--NIPTKVPSAMVGLGQ 1015

  Fly   879 --SGSGDEPTTSQAT---QSAGDAVQAVD----------------GLAG----------LVGDD- 911
              .....:|...|.|   :|..|...|||                .::|          |||||
  Rat  1016 EIQEQSSDPFKKQLTINHESKEDREMAVDSAVTNNRNQEFVSNSRSISGESVVSESDFTLVGDDS 1080

  Fly   912 ----GHR---IKILSQTQ-------------------ILPKKRP------------HAQMVAAAA 938
                .||   :.:|:.:|                   .|||::.            ..|:..:|.
  Rat  1081 GMLVNHRRSTLALLAMSQPGDAASGKTEDEKQDVTYFNLPKEKAKGKEQGKEEEDNQKQLKKSAQ 1145

  Fly   939 AAESAPSSSVI----QQPGDQTSFRPYAQQQ------QQAQQQQQQSMSGQHFVQQHCAQLTAGA 993
            .....|..:.:    ..|..::....:..|:      ::.:::|.:..:|  |:......|..|.
  Rat  1146 CKRQNPRGTDVYLPYTSPSSESCDEGFQHQEKMRQKIKEVEEKQPEVKTG--FIASFLDFLKCGP 1208

  Fly   994 GQD----PLSVPPRREQCSRK----------AKQS-SMHAMLMNSSSVVGDGGV-VGE--PDEFT 1040
            .|.    .:.:|.|..:...:          ||.| :.||:|.:.:     ||| :.|  .:|..
  Rat  1209 KQQFSTLAVRIPNRTRRSGTQVTRTFCPPPFAKTSPAAHALLPSET-----GGVNLSEKVDNELK 1268

  Fly  1041 DSDTDPVWTPQEEDS-----DDGKGYGKRKLARRSKGTPRKNTYD------------HSSGLQQQ 1088
            :.:....::..||||     |..|.......|........|.|..            .::|:...
  Rat  1269 NLEQLSSFSSDEEDSGTCGHDSSKSTSAPLTALDPTSDKTKKTVSETLPVATPGASAETAGVTPT 1333

  Fly  1089 PQQ-----QQQHHQQLQQMQVNQQHHQQQQQ-----------VQQMAGGESTYNSQQNMSGVADV 1137
            |..     :|..|  |..:.||...:....:           ..|:|.|:.|         ||..
  Rat  1334 PSSVVGTVKQDLH--LTSLAVNTVENVNSTEPPTAIELDSLPSDQLAKGQDT---------VAIE 1387

  Fly  1138 GYASASSGPAANSENFKTGDFIVLRSDLVNDW----------PTIWQVDSKCILQKYEPFRQNGK 1192
            |:....:..:.....::..|..|::.:.:..:          |.||:| .|.:|||:.|..::|:
  Rat  1388 GFIDEENVESEGEGQYRERDEFVVKIEDIETFKEALNTGKEPPAIWKV-QKALLQKFVPEIRDGQ 1451

  Fly  1193 TFYRNMSKYASW----NLETKKLYLK--------------------------------------- 1214
            ..:...:.|..:    ..:.|::|:|
  Rat  1452 REFAATNSYLGYFGDAKTKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTVRNIPSKPSSISKT 1516

  Fly  1215 --APVRIQLHSHTETI---------------------------VEFMRSELLADDTEQFIEKIME 1250
              .||     |.|.||                           .||..|:  ::.:.:......|
  Rat  1517 SDPPV-----SKTTTIKAPSTKPKAKQLKVKAEPPPKKRKKWKEEFSSSQ--SESSPEVRSSSSE 1574

  Fly  1251 D------------YLSYR---DNFEIYIQTMISQALDPSFFSEITREKDDYFLGSVRVVDNIMEN 1300
            |            :|:.|   :.|:.|::.::|.||||.....:.:..|:..|..::.:|.::.:
  Rat  1575 DEGFEPPAPSVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLND 1639

  Fly  1301 CKRKLLAITPWTRSTISSIETWPKCHVFSEWEQNNLTQKNCAGCHQPGIAV-RFLLFGEPYNPNT 1364
            .:::||......:...:::|::|:..:.:.      ..|..:|    |.|: :..:.|:.||..|
  Rat  1640 NRKRLLVNLHLDQPFKNALESFPELTIITR------DSKAKSG----GSAISKIKMNGKAYNKKT 1694

  Fly  1365 MQTIPVDPRIVY------------EKDIVLCRICAARA----DLFHKIAHEKFNLFINCSQRVTE 1413
            ::|.....:...            :::||  ::|....    |||     |||...:|      .
  Rat  1695 LRTSKTTTKSAQISSVQKKNEDLGQEEIV--QLCMKNVKWVEDLF-----EKFGELLN------H 1746

  Fly  1414 QQQQFP 1419
            .||:.|
  Rat  1747 VQQKCP 1752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17233	NP_730500.1	DUF4211	1228..1365	CDD:464045	29/179 (16%)
Qser1	XP_038960857.1	Atrophin-1	134..>572	CDD:460830	108/523 (21%)
		ser_rich_anae_1	<376..>672	CDD:468206	72/345 (21%)
		PHA02939	<1429..1489	CDD:222947	14/60 (23%)
		DUF4211	1575..1695	CDD:464045	24/129 (19%)