Protein Alignment CG17233 and qser1

DIOPT Version :9

• Sequence 1: NP_730500.1
• Gene: CG17233 / 40220
• FlyBaseID: FBgn0036958
• Length: 1465
• Species: Drosophila melanogaster
• Sequence 2: XP_005170024.1
• Gene: qser1 / 100330496
• ZFINID: ZDB-GENE-030131-2978
• Length: 1708
• Species: Danio rerio
• Alignment Length: 1771
• Identity: 345/1771 - (19%)
• Similarity: 603/1771 - (34%)
• Gaps: 499/1771 - (28%)

  Fly    20 AGSSGGT-AEDFQHPHLATITAASIASF-NAAAASGGSFVPPSPIGSYN-----PVFQQIYHHAA 77
            ||.:|.| ...|:.|...|...:|...| ..|....|:|..||.:.||.     |.  :.:..|:
Zfish    95 AGPAGSTLLPSFRSPSWQTGANSSTELFLTGALHPSGTFPTPSALSSYQHPSAFPT--RSFTTAS 157

  Fly    78 AASVQPKPAHYASSAVSTPHRQLQLPSSLDKQLSSFQNQAAVSAAAAAVVNNVASNYYGENSSSS 142
            |..||......::..:|:....|||.||    .::.|...|.|..:..|.....|:.|.....|:
Zfish   158 ALGVQDSTFSSSNGLLSSNDSLLQLKSS----QNTVQTALAFSGTSLGVGLPPQSSTYRSAQESA 218

  Fly   143 GASPSPTTVALTSTSL--------TWNTPNMISNTFLAMQQQQAQQQQQQAQQQQQQAQQQQQQA 199
            .....| ..:|.|.||        .::.|....:...|:|::.:..:..|.....|..|:|...:
Zfish   219 PHLLQP-QFSLLSASLGSSQQAPQPYSGPAFSGSIERALQRECSVIKHHQRPSSTQPVQEQLANS 282

  Fly   200 QQQQL-NLVADKVQIKQEKQLKAY--------NDSIYLIQLQQQQQQQQTAAQQQQQQLHQQLQQ 255
            .|..| ..:.|:..:..::.|..:        .|...|    ....||:||:|.|
Zfish   283 AQHSLQGYLHDESDVSYQQDLSPHTPVPCSPVGDPSPL----NGTTQQKTASQTQ---------- 333

  Fly   256 EIAEADTEPDTYYTIDGRKVKVTRKDGQPYRATIVDQQDASPVPLAVPVPAGSYPVQYASP---- 316
              |.|.:.|...:: ....|||  |||....|....:...|.|..:.|   |..|..|:||
Zfish   334 --AYASSVPSPGFS-SSTGVKV--KDGSSSIAQHPSEDTDSQVQTSSP---GLQPQSYSSPTQKQ 390

  Fly   317 -ALSSADGSPITNLHAVDVVST--------------------------PQAQVIVYKTASPVQRR 354
             ::.::...|.|:.....:||.                          |:....:|||.|....:
Zfish   391 SSVIASQLQPYTSTQLTGLVSVSASHTYITSQSLSNSLSQTQAFTSSLPEKLPSIYKTLSSFASQ 455

  Fly   355 QEAGAGSSAAATPTTVAYSSVIQSTLQQQQQQQNLCWTKLEDNGAGQEDIKNVLQLQVKQEHRQL 419
            .|              |.:||.||.:....|||:|      .....:|..:..:|........|
Zfish   456 SE--------------AETSVSQSHIYSSSQQQDL------HPSGNREGYETHVQTHCMGSPSQ- 499

  Fly   420 DFASEASSVDAGGGGENLVFNLPPGLEIKQTFY---PASV-------VDGEQLQ-----LQEHNQ 469
               |.:||...|         ||     ..:||   ||||       |..:.|.     ...:::
Zfish   500 ---SYSSSHSQG---------LP-----TISFYTQGPASVSIPSQNYVSSQSLTSVPSFSSNYSR 547

  Fly   470 NQSQSSGRRQHVVANMIMSP-------------------SAGNLASQIQVVPKE----EVKPPPK 511
            :.|.|:..:.:|:  |..||                   |..:.|:..:|:||:    |:||
Zfish   548 SLSSSNPGQDYVL--MQSSPGSKTDNALLQQKYLLSVQSSTSSAATYTKVLPKDQSSVEIKP--- 607

  Fly   512 PAKTPRKRQPKKTLIPSSSDYGN--------------VRSPQEPQHHQLQQQ----------QQQ 552
                  :::.::..:||.:..|.              |.|||.....::.:|          .:.
Zfish   608 ------RQEDEQMFLPSKASSGELPLEDVQALQKGSLVTSPQNISTSEIGEQNSAKNDIYVVSKM 666

  Fly   553 QQQH--------NQQQQQQNTYYDFNSKWNAPLKTENNAASV------SPAATINIPTYPQ---- 599
            :.:|        |.:.::|......|:|   .|.|..||.|:      |..|.::.....|
Zfish   667 EDRHNTPSVIRSNSRTEEQTLSQMENTK---ELTTNANAKSIPLLMHSSTLAPLSADQLKQHTLL 728

  Fly   600 ----QSQQQQHQQQQAQQQQQQHLPQPAHLQSSQAQ--------------SHLTQLAQYYPAFPQ 646
                .||||.|.:|..|.|    ...|..|...|||              ||:..|       .|
Zfish   729 LKGSSSQQQNHHEQIIQVQ----TTDPRQLSEGQAQFIRVPSTTQVLLDPSHMIVL-------QQ 782

  Fly   647 PIASQYTACMQQQQQQQQQQQQQQQQQAAYTQQQHQQAYT-------QQQQQQAQQQRQEKSEAT 704
            |:.:  ||        |.|.:|....|:...|..|..:.|       :..||....|....:.:|
Zfish   783 PVLT--TA--------QNQPKQTMYMQSVPVQYVHMNSDTVNLTINGRHNQQFVSHQVPNSTGST 837

  Fly   705 QQ--------------QEEEANAAAAAAAAAAASNKVIVPNIEEELDFLADATATPKQGYANSLS 755
            ::              |....|:...:.:...|..:.|:.|:::.|...|.|.....|.:..|.|
Zfish   838 KEDPTLKDQSSPHDIKQNFSLNSVCFSDSMLLADERNILSNVDDILAATAAACGVTPQDFVKSTS 902

  Fly   756 SNGRGTNSSTNNTNFGIRNPNKTPSPEPTNC----PPNSHASNNGHGHSAVTPVAPSSTGASAST 816
            |:|               :.:...:|..:.|    |.|.|.|.... |..:.|.|.:..|  |.|
Zfish   903 SDG---------------DMSSVANPVDSKCNFQSPENRHNSFPSQ-HMIINPQAMTVIG--AQT 949

  Fly   817 AYSPVAPKPVSVGTLI------GEKKTQFMDSYLKFLQGERDDDPPPVVKPSRKLNYPRAPYKRK 875
            .||....:...|.||.      .|:.....|...|........|   |:...|.:|.........
Zfish   950 TYSKEETEGHQVFTLSHSNNQPEERCKSAQDISDKVANAHEKSD---VLSKGRFVNSSNGSLNTN 1011

  Fly   876 G---KGSGSGD----------------EPTTSQATQ-------SAGDAV--QAVDGLA------- 905
            |   ..:.|.|                |..:|..:|       ...|::  .:.||||
Zfish  1012 GLAISNTTSNDFNLANQQQSQSPHHITENVSSNLSQQKELKGFKTNDSIIENSTDGLAKKRSRSK 1076

  Fly   906 ----GLVGDDGHRIKILSQTQILPKKRPHAQMVAAAAAAESAPSSSVIQQPGDQTSFRPYAQQQQ 966
                ....|:..:.|.  |.:.:..||.:::....:..:.|..|....||   |...|   |:.:
Zfish  1077 GSSKQTAEDENGQPKF--QKKSIQVKRQNSRANETSTTSASEVSHDNFQQ---QEKMR---QKLK 1133

  Fly   967 QAQQQQQQSMSGQHFVQQHCAQLTAGAGQDPLSVPPRREQCSRKAKQSSM--HAMLM-------- 1021
            :.:::|.:..:|  |:......|.:|:.|:..|.|.|....:||:..|..  :.:|:
Zfish  1134 EVEEKQPEVKTG--FLGSFLDFLKSGSRQNLSSPPIRSPNRTRKSSASKRPPNPLLIPFKPPPPV 1196

  Fly  1022 ------NSSSVVGDGGVVGEPDEFTDSDTDPVWTPQEEDSDDGKGYGKRKLARRSKGTPRKNTYD 1080
                  ...||:....:..|...  :.:|.|.::..||||     .||.:..::|. |...::.|
Zfish  1197 TPLISPEPQSVISTKRLDEELQR--NLETLPSFSSDEEDS-----VGKNQDLQKSI-TSALSSLD 1253

  Fly  1081 HSSGLQQQ--PQQQQQHHQQLQQMQVNQQHHQQQQQVQQMAGGESTYNSQQNMSGVADVGYASAS 1143
            ..|..:|:  ...:|......|.:.|:||...::...:.:.....|......::.||..|.....
Zfish  1254 EPSDKKQKLGDNVKQLQTSSTQPVVVDQQKSVEKISAEDLLKDVPTDKLAVQLNAVAIEGLIDEE 1318

  Fly  1144 SGPAANSENFKTGD-FIVLRSDLVN---------DWPTIWQVDSKCILQKYEPFRQNGKTFYRNM 1198
            ...:.....::..| |:|...|:..         :.|.||:| .|.:|||:.|..::||..:...
Zfish  1319 LSDSGGEGMYRERDEFVVKNEDIERLTVTLKAGVEPPAIWKV-QKALLQKFVPELRDGKRVFFAT 1382

  Fly  1199 SKYASWNLETKKLYLKAPVRI--------------------QLHSHTETIVEFMRSELLADDT-- 1241
            :.|..:..:.|.:|.:..|:.                    .:||...:..:.:.::..|..|
Zfish  1383 NSYLGYFGDAKLMYRRVHVKFLDTVNKREYVRVCSRKPQCKPMHSMRSSQAKALLAQRFAAATAS 1447

  Fly  1242 ------------------------------------EQFI--------EKIMED----------- 1251
                                                |:|.        |.:.||
Zfish  1448 DCATQKTAQQKALSKPKPKQPKAKAEPPPKKRKKWKEEFTSSPSDSSPEAVSEDDEFTPPVPFAS 1512

  Fly  1252 -YLSYR---DNFEIYIQTMISQALDPSFFSEITREKDDYFLGSVRVVDNIMENCKRKLLAITPWT 1312
             :|:.|   :.|:.:::.::|.|||....:.:.||.|:..|..::.||.::.:.:|:||......
Zfish  1513 RFLNTRTMKETFKSFVELLVSVALDADVLNALERENDELLLPHMKRVDGMITDNRRRLLPKLRMG 1577

  Fly  1313 RSTISSIETWPKCHVFSEWEQNNLTQKNCAGCHQPGIAVRFLLFGEPYNPNTMQ------TIPVD 1371
            :...::::.:|:..|.:|.:.:         |..|...||  |.|..||..||:      .:|::
Zfish  1578 QIFKNALDCFPELSVVTELKTD---------CETPVFKVR--LSGRAYNKKTMKPSKSPSKLPLE 1631

  Fly  1372 PRIVYEKDIVLCRICAARADLFHKIAHEKFNLFINCSQRVTEQQQQFPGKTSTEILNDLLAEHNW 1436
            ..:..:|        .....|:|.:.|.|::.::.|.:.:...:.:.......|.:...:...:|
Zfish  1632 YTVDQQK--------TKWFSLYHSLQHYKYHTYLMCVEEIELLKSRGRDLGQEETVQTCMGNRSW 1688

  Fly  1437 IDELFRNMRNCWAEVE 1452
            ::.||........:|:
Zfish  1689 VEGLFDRFGELLTQVQ 1704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17233	NP_730500.1	DUF4211	1234..1372	CDD:290637	37/204 (18%)
qser1	XP_005170024.1	DUF4211	1491..1626	CDD:290637	32/145 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I12376
eggNOG	1	0.900	-	-		E1_KOG4805
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26119
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5203
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930