Protein Alignment CG17233 and qser1

DIOPT Version :10

• Sequence 1: NP_730500.1
• Gene: CG17233 / 40220
• FlyBaseID: FBgn0036958
• Length: 1465
• Species: Drosophila melanogaster
• Sequence 2: XP_004913508.3
• Gene: qser1 / 100036640
• XenbaseID: XB-GENE-6257598
• Length: 1771
• Species: Xenopus tropicalis
• Alignment Length: 1887
• Identity: 352/1887 - (18%)
• Similarity: 630/1887 - (33%)
• Gaps: 567/1887 - (30%)

  Fly     2 DP--NSSPWSYAYNR----IVPA-SAGSSGGTAEDFQ--------------------HP------ 33
            ||  ::||.::||.|    |.|: |.|:...|..:.:                    ||
 Frog    12 DPLASASPAAWAYERSAAGIKPSLSYGAGHPTHSETELLHRQTYAATHQLPGYATAHHPTGLSGI 76

  Fly    34 -----HLA--TITAASIASF-------NAAAASGGSFVPPSPIGSYNPVFQQIYHHAAAASVQPK 84
                 |:|  ..|..|:.:|       .|.|||.|:.:.|.   ...|.:|...|.:||..:
 Frog    77 FDTSLHVAGSNTTETSVMNFLSAIESRTAQAASSGTTLLPQ---FRAPSWQTGMHSSAATEL--- 135

  Fly    85 PAHYASSAVSTPHRQLQLPSSLDKQLSSFQNQAAVSAAAAAVVNNVASNYYGENSSSSG-ASP-- 146
               :.:.|:.|..   ..|:|   .|:::|:....|:...|...::|......:::::| .||
 Frog   136 ---FVTGALQTSG---TFPTS---ALTAYQHPNTFSSRNFATTPSLALQDGTFSATTNGLLSPHD 191

  Fly   147 -------SPTTVALT-----STSLTWNTPNMISNTFLAMQQQQAQQQQQQAQ-------QQQQQA 192
                   |.|..|||     |..|:.:.|.  |:|:.:.|:......|.|..       ..||.|
 Frog   192 PLLQIKTSQTPTALTFERIGSAVLSTSIPQ--SSTYRSAQESAPHLLQPQFSLLPTALGGTQQPA 254

  Fly   193 QQQQ-----------QQAQQQQLNLV--------ADKVQIK---QEKQLKAYNDSIYLIQLQQQQ 235
            |...           ::|.|::.:::        ...||.:   .:..|..|..|:..:.||...
 Frog   255 QPYSTSVFTGSTASIERALQRECSVIKHHQRPSSTQSVQAQLSGTQHSLPNYLTSVSGVSLQDAS 319

  Fly   236 QQQQTAAQ-------------QQQQQLHQQLQQEIAEADTEPDTYYTIDGRKVKVTRKDGQPYRA 287
            :|....|.             |:..|:..:|.|........|       |.....|:....|.:|
 Frog   320 RQSLLCAPLGALTQVSNGGPVQKTSQVSVELSQSYPSVIPSP-------GYPPSSTKSKNCPTKA 377

  Fly   288 TIVDQQDASPVPLAVPVPAGSY---PVQYAS--------------PALSSADGSPI-TNLHAVDV 334
            .....:......:..|....||   |...:|              |:|.|...||| .:..:.::
 Frog   378 PPRSSKTPKSQSVVSPEQTQSYTKSPQNQSSVNSSQAQAFSTAQLPSLLSVSQSPIYVSTQSPNL 442

  Fly   335 VSTPQAQVI----------VYKTASPVQRRQE---AGAGSSAAATPTTVAYSSVIQSTLQQQQQQ 386
            .|..|:||.          :||..:....:.:   :|:.:.:.::..:::.|||...|...|.:.
 Frog   443 PSASQSQVFSTIKTEKLPPLYKPLTAFSSQSQTITSGSQTLSYSSDQSLSLSSVSSETYSDQTRD 507

  Fly   387 QNLCWTKLEDNGAGQEDIKNVLQLQVKQEHRQLDFASEASSVDAGGGGENLVFNLPPGLEIKQTF 451
            .:........:....:.:.:|.|.||... .|....|..|..|:...|:||....|.
 Frog   508 LSSANQSQSYSSNNSQGLTSVSQSQVSYS-SQSQVMSPVSPSDSYTSGQNLTLASPS-------- 563

  Fly   452 YPASVVDGEQLQLQEHNQNQSQSSGRRQHVVANMIMSPSAGNLAS-QIQ-----VVPKEEVKPP- 509
            .|.|.        ....||.|.||..:..:  :|..:|:..:..| |.|     |.|.....||
 Frog   564 LPFSA--------SSRGQNLSASSPTQNFI--SMHPTPNTQDSTSPQSQKFLPSVQPSSFASPPH 618

  Fly   510 PKPAKTPRKRQPKKTLIPSSSDYGNVRSPQEPQHHQLQQQQQQQQ-------------------- 554
            .:..:..|.....|:.:...||.....|.::.:..|:|..|..||
 Frog   619 SQSMQNSRTTADSKSYVKRKSDTNLYSSAKQEEKFQIQDLQALQQTTLETATPGLSEGELSTQET 683

  Fly   555 ----------------QHNQQQQQQ---------------------------NTYYDFNSKWNAP 576
                            :.|.:.:.|                           |.....:.|.|..
 Frog   684 AYSVSKADDRYSQSVIKSNSRMEDQVLGLQGTKKDERLISPVGHMSQHVSHLNNSASHDGKKNTD 748

  Fly   577 L--KTENNAASVSPAATIN-IPTYPQQSQQQQHQQQQAQQQQQQHLPQP---------------- 622
            |  .|:.:|..:|....:: :.....|.|.....|.||..:..|||..|
 Frog   749 LIQSTQVSAKDLSQHTMLHKVLDTKMQEQPSTSPQIQAAMRHSQHLQLPGAQVLLDSGCDLQMFQ 813

  Fly   623 -AHLQSSQAQSHLTQLAQYYPAFPQPIASQYTACMQQQQQQQQQQQQQQQQQAAYTQ-------- 678
             :.|||:..|:......|...:.|| :|.|:.    |...|..|....|.||:.:.|
 Frog   814 QSILQSNMGQAKTPAQMQRIQSPPQ-VAHQFL----QMDGQIIQSNGAQPQQSLHAQGSEVIKMD 873

  Fly   679 ---QQHQQAYTQQQQQQAQQQRQEKSEATQQQEEEANAAAAAAAAAAASNKVIVPNIEEELDFLA 740
               .:|.|.:...:...:|:.|.:    ::.|.:..|......:...:..:..:.:::   |.||
 Frog   874 TSDGKHLQQHLHTKDHFSQRGRLD----SKNQFDSLNPMCFTESMLLSDERNFLSHVD---DILA 931

  Fly   741 DATATPKQGYANS-----LSSNGRGTNSSTNNTNFGIRNPNKTPSPEPTNCPPNSHASNNGHGHS 800
               ||..|.:|.|     ||...:...|...:.|....:||.|| |:|.|.  || .|.||
 Frog   932 ---ATAAQEFAKSSNEENLSVKNQDAKSRFQSLNVRHMSPNFTP-PKPQNM--NS-LSLNG---- 985

  Fly   801 AVTPVAPSSTGASASTAYSPVAPKPVSVGTLIGEKKTQFMDSYLKF-LQGERDDDPPPVVKPSRK 864
                   |.|..:.||. |...||.||:.....:...|.:.|.::. :.|...:|.....:..:|
 Frog   986 -------SQTAINLSTV-STTQPKNVSLDQTHIQPMEQDLPSGMRSPVLGANQEDHEKNSEKIKK 1042

  Fly   865 LNYPRAPYKRKGKGSG------------SGDEPTTSQATQSAGDAVQAVDGLAGLVGDDGHRIKI 917
            .|..:.|     |.||            |.::..:.:.|.|.||.:..        ||:...:..
 Frog  1043 SNINQEP-----KESGNIPEEVRDAEFLSNNKTLSEENTTSEGDFIMG--------GDENSSLGQ 1094

  Fly   918 LSQTQILPKKRPHAQMVAAAAAAESAP--SSSVIQQPGDQTSFRPYAQQQQQAQQQQQQSM---- 976
            : |.|.|.|..|.|...:.:...|..|  |...:|:..|:...:.:.:.:....:|.:::|
 Frog  1095 V-QGQQLSKIDPQAGGSSTSQMEEDCPDLSQDGLQKGKDKMPIKQFTEDENANLKQIKRNMPLKR 1158

  Fly   977 -----------------------SGQH---------------------FVQQHCAQLTAGAGQD- 996
                                   |.||                     |:......|..|..|.
 Frog  1159 PISKGPDVPGVQYSSHVSEGYYDSYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKTGPKQQF 1223

  Fly   997 ---PLSVPPR---------REQCSRKAKQSSMHAMLMNSSSVVGDGGVVGEPDEFTDS-----DT 1044
               .:.||.|         |..|.....|.|:      :.:.|.|.|....|.:..:.     :|
 Frog  1224 SAPAVRVPNRVRRPCTPVIRAPCPGPVSQQSV------AGAPVSDSGSTSPPKKAEEDLKKNLET 1282

  Fly  1045 DPVWTPQEEDSDDGKGYGKRKLAR-------------RSKGTPRKNTYDHSSGLQQQPQQQQQHH 1096
            .|.::..|:|:..|....::.::.             :|:|.....:..........|:..|...
 Frog  1283 LPSFSSDEDDATVGNNDLQKSISTALSALDDNSEKKIKSEGDKAVVSAKQDPSASSTPRNGQDKT 1347

  Fly  1097 QQLQQMQVNQQHHQQQQQVQQMAGGESTYNSQQNMSGVADVGYASASSGPAANSENFKTGD-FIV 1160
            :..:.::.:|....|.:|:.:         ||:   .:|..|:....:..:.....::..| |:|
 Frog  1348 KAQESLKPSQPEPTQPEQLAK---------SQE---AIAIEGFTDEENAESGGEGIYRERDEFVV 1400

  Fly  1161 LRSDLV---------NDWPTIWQVDSKCILQKYEPFRQNGKTFYRNMSKYASW----NLETKKLY 1212
            ...|:.         .:.|.||:| .|.:|||:.|..::|:..:...:.|..:    ..:.|::|
 Frog  1401 KIEDIEMLKEALRSGKEPPAIWKV-QKALLQKFIPEIRDGQRSFAATNSYLGYFGDAKTKYKRVY 1464

  Fly  1213 LK-----------------------APVRIQLHSHTET------------------IV------- 1229
            :|                       .|.|.   :||:.                  :|
 Frog  1465 VKFVENANKKEYVRVCSRKPKSKILPPART---THTKASGGSKVSETPPPKSAPPKVVSAKPKAK 1526

  Fly  1230 ------------------EFMRSEL-----LADDTEQF---IEKIMEDYLSYR---DNFEIYIQT 1265
                              ||..|:.     :..|.|:|   ...|:..:|:.|   :.|:.||:.
 Frog  1527 QQKTKAEPPPKKRKQWKEEFSSSQSDSSPDMQSDEEEFEPPPPPIVTRFLNTRAMKETFKGYIEL 1591

  Fly  1266 MISQALDPSFFSEITREKDDYFLGSVRVVDNIMENCKRKLLAITPWTRSTISSIETWPKCHVFSE 1330
            ::|..||......:.:|.||..|..:|.::.::...:|:||......:...:::|.:|...:.:
 Frog  1592 LVSLTLDGDMMQNLEKENDDVLLPHMRKIEGMLNENRRRLLTKLQLEQPLKNALENYPDFAIIT- 1655

  Fly  1331 WEQNNLTQKNCAGCHQPGIAVRFLLFGEPYNPNTM----------QTIPVDPRIVYEKDIVLCRI 1385
                    :...|......|.:..:.|:.||..|:          |..||:|    ||.    ::
 Frog  1656 --------RETKGKSGGAAACKIKVNGKWYNKKTLRPAKNPSKQSQEFPVEP----EKS----QL 1704

  Fly  1386 CAARADLFHKIAHEKFNLFINCSQRVTEQQQQFPGKTSTEILNDLLAEHNWIDELFRNMRNCWAE 1450
            |:    |:|.:.|.|:::::.|.:.|:..|:........|::|..|....|:::||.......:.
 Frog  1705 CS----LYHALHHYKYHIYLICKEEVSSVQKANRDLKHEELVNHCLKNMKWVEDLFEKFGELLSR 1765

  Fly  1451 VE 1452
            |:
 Frog  1766 VQ 1767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17233	NP_730500.1	DUF4211	1228..1365	CDD:464045	31/172 (18%)
qser1	XP_004913508.3	Atrophin-1	109..>465	CDD:460830	73/379 (19%)
		PTZ00121	<1265..>1545	CDD:173412	40/295 (14%)
		DUF4211	1573..1682	CDD:464045	23/117 (20%)