DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Su(var)3-3 and PAO4

DIOPT Version :9

Sequence 1:	NP_649194.1	Gene:	Su(var)3-3 / 40217	FlyBaseID:	FBgn0260397	Length:	890	Species:	Drosophila melanogaster
Sequence 2:	NP_176759.1	Gene:	PAO4 / 842894	AraportID:	AT1G65840	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	160/569 - (28%)
Similarity:	233/569 - (40%)	Gaps:	163/569 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 VIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFRKNSYIADVGAMVVTGVYG-NPMTI 330
            |||||:||||||.|..|.:....|.|||:|||:||||.|........|:||..:.||.. ||:..
plant    31 VIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVSDENPLAP 95

  Fly   331 LSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLESASYLSHRLDFNYAGD-CPVSL 394
            :.:::|:         .||...|       ||.|  .::..|||...      |:..|: .|..|
plant    96 IIRRLGL---------TLYRTSG-------DDSI--LYDHDLESYGL------FDMHGNKIPPQL 136

  Fly   395 ----GDALEWIISMQEMQVMHKRGQHMQEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMINQR 455
                |||.:.|:...|                                    |:::|
plant   137 VTKVGDAFKRILEETE------------------------------------KIRDE-------- 157

  Fly   456 KPKGTDGDLKYCYQEFNI---RNTQIKMEETISTFHDLHAEEKQMLAKLHELEQNRPSDVYLSSR 517
                |..|:. ..|..:|   ||.:::.|                 ...:|
plant   158 ----TANDMS-VLQGISIVLDRNPELRQE-----------------GMAYE-------------- 186

  Fly   518 DRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVPVALTENLDIRVNSA 582
               :|.|:...:|...|...|.:|||.||||:...  |.|..:..||..|...:.::||||:|..
plant   187 ---VLQWYLCRMEAWFAVDANLISLKCWDQDECLS--GGHGLMVQGYEPVIRTIAKDLDIRLNHR 246

  Fly   583 VKEIKYGTKGVEVVAENLKTSNSQM--------TYKADLVVCTLTLGVLKVAVAHKESQQSNTVK 639
            |.::             ::|||:::        .:.||.|:.|:.:||||          :|.::
plant   247 VTKV-------------VRTSNNKVIVAVEGGTNFVADAVIITVPIGVLK----------ANLIQ 288

  Fly   640 FDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVGSTTASRGEMFLFWSISSSPVL 704
            |:|.||.||..||..||.||.||:.|.|||.|| ||....|.|..|:.:.|........:..|||
plant   289 FEPELPQWKTSAISGLGVGNENKIALRFDRAFW-PNVEFLGMVAPTSYACGYFLNLHKATGHPVL 352

  Fly   705 LALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTRWRSDPWARGSYSYVSVGS 769
            :.:.||..|..:|.::|:......|..||.:|  ...|.|.:.:||||.:||...|.|:|..||.
plant   353 VYMAAGNLAQDLEKLSDEATANFVMLQLKKMF--PDAPDPAQYLVTRWGTDPNTLGCYAYDVVGM 415

  Fly   770 SGSDYDLLAAPVIPPSSKDAEGLPRLFFAGEHTIRNYPATVHGAYLSGL 818
            ....|..|..||           ..:||.||.....:..:.|||:|:|:
plant   416 PEDLYPRLGEPV-----------DNIFFGGEAVNVEHQGSAHGAFLAGV 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	SWIRM	165..250	CDD:282311
		NAD_binding_8	269..327	CDD:290186	28/58 (48%)
		Amino_oxidase	274..824	CDD:279874	154/562 (27%)
PAO4	NP_176759.1	PLN02268	29..464	CDD:177909	160/569 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1231
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1034142at2759
OrthoFinder	1	1.000	-	-		FOG0001117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920