Protein Alignment Su(var)3-3 and 4930438A08Rik

DIOPT Version :10

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_001361634.1
• Gene: 4930438A08Rik / 73988
• MGIID: 1921238
• Length: 536
• Species: Mus musculus
• Alignment Length: 626
• Identity: 139/626 - (22%)
• Similarity: 230/626 - (36%)
• Gaps: 207/626 - (33%)

  Fly   253 FKRLKPIPAKKLG------KVIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFR---K 308
            ::.|..:....||      :|:|||||::||..|..||..|..|.||||..||||||.|.|   .
Mouse    44 YEELLQLARNGLGQTAERKQVVVIGAGMAGLTAAKILQDAGHQVTVLEASGRVGGRIETHRVPGA 108

  Fly   309 NSYIADVGAMVVTGVYGNPMTILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLE 373
            :.|| ::|||.:.         ::.::..:|:                  :|..::.:||
Mouse   109 HWYI-ELGAMRIP---------INHRLSHELI------------------KKFGLMLKEF----- 140

  Fly   374 SASYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHKRGQHMQ-------------EIIATQT 425
                            ||.   :...|::    :..:.:|...:|             |:..|..
Mouse   141 ----------------CPC---NNQTWVL----VNGVRQRSGAVQADPGLLGYSVRADEVGKTAE 182

  Fly   426 KIIEQRRRLKTLRDTIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDL 490
            ::.:     .:||..:.:|||.....:.::            |..|:.:...||:       .:|
Mouse   183 QLFD-----ASLRKIVEELKNSSCQEVLEK------------YDSFSTKEYLIKV-------GNL 223

  Fly   491 HAEEKQMLAKLHELEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDF-EFI 554
            .....||:..:    .|..|..|.:               |....|    .:..:.||..| |.:
Mouse   224 SRGAVQMIGDM----LNTDSGYYEA---------------FTETLR----GIISFFQDPRFDEIV 265

  Fly   555 GHHTTVRNGYSCVPVALTENL---DIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVC 616
            |       |:..:|.||..:|   .:...|..:|::.....|.|..........:....||.||.
Mouse   266 G-------GFDQLPQALHNSLLPGTVWFYSPAEEVEMSGDCVHVTYRTPDPLLPRARLTADFVVV 323

  Fly   617 TLTLGVLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGH 681
            ..|            ::.:..::|.|||...||.|::.:.:.:..||:|...:.||:.: .:|.
Mouse   324 ATT------------AKAARLLRFQPPLSLNKQDALRSVHYNSATKVILACTQRFWERD-GIFS- 374

  Fly   682 VGSTTASRGEMFLFWSISSSP----VLLA----------LVAGMAANLVESVTDDI--IIGRCMS 730
             |.::..|...|:::.....|    |:||          ..|.....:|:.|.||:  :..|...
Mouse   375 -GKSSTDRPSRFIYYPNHIFPNGAGVILASYTLDDDSVFFTALDHTQVVDIVLDDLAALHSRAKE 438

  Fly   731 VLKNIFGNTSVPQPKETVVTRWRSDPWARGS------YSYVSVGSSGSDYDLLAAPVIPPSSKDA 789
            .|:.:     .|.   :.:..|..||::.|.      |.||       ||   |..:..|
Mouse   439 ELRAL-----CPY---SAIKNWSQDPYSMGGFAFFTPYQYV-------DY---AQELSQP----- 480

  Fly   790 EGLPRLFFAGEHTIRNYPATVHG----AYLSGLREAGRIAD 826
            |||  :|||||||  :.|   ||    |..||||.|..|.:
Mouse   481 EGL--VFFAGEHT--DLP---HGWIDTAIKSGLRVAKNIQE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	PLN03000	74..>827	CDD:178578	139/626 (22%)
4930438A08Rik	NP_001361634.1	YobN	55..512	CDD:440844	137/611 (22%)