Protein Alignment Su(var)3-3 and smox

DIOPT Version :10

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_001039135.1
• Gene: smox / 733959
• XenbaseID: XB-GENE-5840847
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 665
• Identity: 169/665 - (25%)
• Similarity: 268/665 - (40%)
• Gaps: 193/665 - (29%)

  Fly   216 SFEIALKNLPPPFDSEPSLVRRVHSFLERHGFINFGIFKRLKPIPAKKLGKVIVIGAGISGLAVA 280
            |.||:......|..|.|          .||                 :..::::||||::||:.|
 Frog     3 SCEISSDGTDDPLSSGP----------RRH-----------------RQPRIVIIGAGLAGLSAA 40

  Fly   281 HQLQQFGM-DVIVLEARDRVGGRISTFRKNSYIADVGAMVVTGVYGNPMTILSKQIGMDLVPIQQ 344
            ..|.:.|. ||.:|||.||:|||:.:.:......::||..:.|..|||:..|::..|:    :::
 Frog    41 KTLLEKGFTDVTILEASDRIGGRVQSIKLEHATFELGATWIHGSNGNPIYHLAEDNGL----LEE 101

  Fly   345 TCPLYGPDGKPVPKEKDDVIEREFNRL-LESASYLSHRLDFNYAGDCPVSL----GDALEWIISM 404
            |     .||           ||...|: |.|.:.::|.|. |.....|..|    .|....:.::
 Frog   102 T-----TDG-----------ERSVGRISLYSKNGVAHYLT-NSGHRIPKDLVEEFSDVYNEVYNL 149

  Fly   405 QEMQVMHKRGQ----HMQEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMINQRKPKGTDGDLK 465
              .|...:.|:    ..|..:...|:.: .|:|:|...|.....|...|||:
 Frog   150 --TQEFFQNGKPVNAESQNSVGVFTRDV-VRKRIKEDPDDSESTKKLKLAMV------------- 198

  Fly   466 YCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAKLHELEQNRPSDVYLSSRDRLILDWHFANLE 530
               |:|      :|:|...|:.|.:                   .:|.||              |
 Frog   199 ---QQF------LKVESCESSSHSM-------------------DEVSLS--------------E 221

  Fly   531 FANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGY--------SCVPVALTENLDIRVNSAVKEIK 587
            |...|                |..|.|..:..|:        |.||.:|     |::...||.:.
 Frog   222 FGEWT----------------EIPGAHHVIPCGFIRIVEILSSSVPKSL-----IQLRKPVKCVH 265

  Fly   588 YG---TKGVEVVAENLKTSNSQMTYK---------------ADLVVCTLTLGVLKVAVAHKESQQ 634
            :.   .|.::.||::   :|.|:..|               ||.|:.|.:|||:|         :
 Frog   266 WNRSIRKQIDRVADH---NNDQVEDKGYPVFVECEDYEFIAADHVIVTASLGVMK---------K 318

  Fly   635 SNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHV-----GSTTASRGEMFL 694
            .:...|.|.||:.|..||.:||....:|:.|.|:..||.|..|....|     .|.:.:..|...
 Frog   319 FHETLFRPSLPEEKVTAIDKLGISTTDKIFLEFEEPFWSPECNSIQFVWEDEAESESLTYPEELW 383

  Fly   695 FWSISSSPVLL----------ALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVV 749
            :..|.|..||.          ..:.|..|.::|...|:.:...|..:|:...||.::|:|:..:.
 Frog   384 YKKICSFDVLYPPERYGYVLSGWICGEEALIMEKYDDETVAETCTELLRKFTGNPNIPKPRRIMR 448

  Fly   750 TRWRSDPWARGSYSYVSVGSSGSDYDLLAAPVIPPSSKDAEGLP-RLFFAGEHTIRNYPATVHGA 813
            :.|.|:|:..|||||..|||||.|.:.||.|:  |.::.::..| ::.|:||.|.|.|.:|.|||
 Frog   449 SSWGSNPYFFGSYSYTQVGSSGEDVEKLAKPL--PYTESSKTAPLQVMFSGEATHRKYYSTTHGA 511

  Fly   814 YLSGLREAGRIADYY 828
            .|||.|||.|:|:.|
 Frog   512 LLSGQREADRLAEMY 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	PLN03000	74..>827	CDD:178578	168/662 (25%)
smox	NP_001039135.1	PLN02568	23..526	CDD:215308	160/616 (26%)