Protein Alignment Su(var)3-3 and Maoa

DIOPT Version :9

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_387502.1
• Gene: Maoa / 29253
• RGDID: 61898
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 654
• Identity: 132/654 - (20%)
• Similarity: 225/654 - (34%)
• Gaps: 191/654 - (29%)

  Fly   257 KPIPAKKLGKVIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFRKNSYI--ADVGAMV 319
            ||..|..:..|:|||.||||||.|..|.::.::|:|||||||||||..|.| |.::  .|||...
  Rat     6 KPNLAGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVR-NEHVKWVDVGGAY 69

  Fly   320 VTGVYGNPMTILSKQIGMDLVPIQ-----------QTCPLYGPDGKPVPKEKDDVIEREFNRLLE 373
            | |...|.:..|||::|::...:.           :|.|..|    ..|...:.:...::|.|..
  Rat    70 V-GPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRG----AFPPVWNPLAYLDYNNLWR 129

  Fly   374 SASYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHKRGQHMQEIIATQTKIIEQRRRLKTLR 438
            :...:...:..    |.|.....|.||                             .:..:|.|.
  Rat   130 TMDEMGKEIPV----DAPWQARHAQEW-----------------------------DKMTMKDLI 161

  Fly   439 DTIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAKLHE 503
            |.|...|              |..:..|.:...|:          .|..|::.|
  Rat   162 DKICWTK--------------TAREFAYLFVNINV----------TSEPHEVSA----------- 191

  Fly   504 LEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVP 568
                            |...|:..  :.....|:  .|:.:..|:.  :|:|....|
  Rat   192 ----------------LWFLWYVR--QCGGTARI--FSVTNGGQER--KFVGGSGQV-------- 226

  Fly   569 VALTENL------DIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLGVLKVAV 627
               :|.:      .::::|.|..|.....  .::.|.|...:.:..|....:...||.
  Rat   227 ---SEQIMGLLGDKVKLSSPVTYIDQTDD--NIIVETLNHEHYECKYVISAIPPILTA------- 279

  Fly   628 AHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFW------------DPNANLFG 680
                     .:.|.|.||..:.|.|:||..|.:.|.::.:...||            |..|.:..
  Rat   280 ---------KIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAI 335

  Fly   681 HVGSTTASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPK 745
            .:..|...          .|.|.::..:....|:.:..:..||...:...:...:.|:.....|.
  Rat   336 TLDDTKPD----------GSLPAIMGFILARKADRLAKLHKDIRKRKICELYAKVLGSQEALYPV 390

  Fly   746 ETVVTRWRSDPWARGSY-SYVSVGSSGSDYDLLAAPVIPPSSKDAEGLPRLFFAGEHTIRNYPAT 809
            ......|..:.::.|.| :|...|.......::..||           .|::|||..|...:...
  Rat   391 HYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPV-----------GRIYFAGTETATQWSGY 444

  Fly   810 VHGAYLSGLREA-------GRIA--DYYLGYPEG--TPP-DIGYSVAEAANLVSVGNVVKLRDLS 862
            :.||..:|.|.|       |::|  |.::..||.  .|. :|.::..| .||.||..::|:..:|
  Rat   445 MEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLE-RNLPSVPGLLKITGVS 508

  Fly   863 PNLS 866
            .:::
  Rat   509 TSVA 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	SWIRM	165..250	CDD:282311
		NAD_binding_8	269..327	CDD:290186	31/59 (53%)
		Amino_oxidase	274..824	CDD:279874	111/588 (19%)
Maoa	NP_387502.1	YobN	15..463	CDD:224152	115/593 (19%)
		NAD_binding_8	18..84	CDD:290186	35/67 (52%)
		Interaction with membrane phospholipid headgroups. /evidence=ECO:0000250	520..522

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1231
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1034142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820