Protein Alignment Su(var)3-3 and Smox

DIOPT Version :9

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_001171304.1
• Gene: Smox / 228608
• MGIID: 2445356
• Length: 585
• Species: Mus musculus
• Alignment Length: 671
• Identity: 170/671 - (25%)
• Similarity: 254/671 - (37%)
• Gaps: 204/671 - (30%)

  Fly   251 GIFKRLKPIPAKKLGKVIVIGAGISGLAVAHQLQQFGM-DVIVLEARDRVGGRISTFRKNSYIAD 314
            |:.:|.:|       :|:|||||::|||.|..|.:.|. ||.||||...:|||:.:.|......:
Mouse    18 GLRRRGQP-------RVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRLGDTTFE 75

  Fly   315 VGAMVVTGVYGNPMTILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRL-LES---- 374
            :||..:.|.:|||:..|::..|:    :::|     .||           ||...|: |.|
Mouse    76 LGATWIHGSHGNPIYQLAEANGL----LEET-----TDG-----------ERSVGRISLYSKNGV 120

  Fly   375 ASYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHKRGQHMQEI----IATQTKIIEQRRRLK 435
            |.||::| ......|......|....:.:|.:....|.:..:.:..    :.|:.|:   |.|::
Mouse   121 ACYLTNR-GCRIPKDVVEEFSDLYNEVYNMTQEFFRHGKPVNAESQNSVGVFTREKV---RNRIR 181

  Fly   436 TLRDTIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAK 500
            ...|.....|...||||.|                      .:|:|...|:.|.:
Mouse   182 DDPDDTEATKRLKLAMIQQ----------------------YLKVESCESSSHSI---------- 214

  Fly   501 LHELEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYS 565
                     .:|.||                         :...|.     |..|.|..:.:|:.
Mouse   215 ---------DEVSLS-------------------------AFGEWT-----EIPGAHHIIPSGFM 240

  Fly   566 CVPVALTENLD---IRVNSAVKEIKYG-----TKGVEVVA-----ENLKT-------SNSQM--- 607
            .|...|.|.:.   |::...|:.|.:.     .:|.|:..     .|..|       .|.|.
Mouse   241 RVVELLAEGIPPHVIQLGKPVRCIHWDQASAHPRGPEIEPRGEGDHNHDTGEGGQSGENPQQGRW 305

  Fly   608 ----------------TYKADLVVCTLTLGVLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLG 656
                            ...||.|:.|::|||||         :..|..|.|.||..|..||.|||
Mouse   306 DEDEPWPVVVECEDCEVIPADHVIVTVSLGVLK---------RQYTSFFRPCLPTEKVAAIHRLG 361

  Fly   657 FGNLNKVVLCFDRIFWDPNANLFGHVGSTTASR---------------GEMFLFWSISSSPVLLA 706
            .|..:|:.|.|:..||.|..|....|....|..               |...|:.......||..
Mouse   362 IGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESCTLTYPPELWYRKICGFDVLYPPERYGHVLSG 426

  Fly   707 LVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTRWRSDPWARGSYSYVSVGSSG 771
            .:.|..|.::|...|:.:...|..:|:...||.::|:|:..:.:.|.|:|:.||||||..|||||
Mouse   427 WICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSG 491

  Fly   772 SDYDLLAAPV-IPPSSKDAEG----------LP------------------RLFFAGEHTIRNYP 807
            :|.:.||.|: ...|||.|..          ||                  ::.|:||.|.|.|.
Mouse   492 ADVEKLAKPLPYTESSKTAHRSSTEQQPGHLLPSKCPEQSLDPSRGSIKPMQVLFSGEATHRKYY 556

  Fly   808 ATVHGAYLSGLREAGRIADYY 828
            :|.|||.|||.|||.|:.:.|
Mouse   557 STTHGALLSGQREAARLIEMY 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	SWIRM	165..250	CDD:282311
		NAD_binding_8	269..327	CDD:290186	25/58 (43%)
		Amino_oxidase	274..824	CDD:279874	159/642 (25%)
Smox	NP_001171304.1	PLN02568	50..578	CDD:215308	155/632 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2622
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940