Protein Alignment Su(var)3-3 and lsd-1

DIOPT Version :10

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_510000.2
• Gene: lsd-1 / 181369
• WormBaseID: WBGene00011615
• Length: 737
• Species: Caenorhabditis elegans
• Alignment Length: 796
• Identity: 202/796 - (25%)
• Similarity: 331/796 - (41%)
• Gaps: 142/796 - (17%)

  Fly    89 SGDTASNDKSGSAS--------------MGPNNQQAERRSQSQTRKSEANATSSSVSGPSAGNSR 139
            :.|.:.:...||:|              :|..|::.:          ::|..:...|.|
 Worm     9 ANDDSQSSSEGSSSTTPQFIPQVPFDFNLGSINEEVD----------DSNGLTGIASVP------ 57

  Fly   140 PSQNGDSKD-----RDAGTPTVLSGQEGAVFQSRLPFNKMTPNEEACFPDISRSGILGHRVFLNI 199
                   ||     ||..:...::.:.|      :..::.|..|.|.||::..|..... |||.|
 Worm    58 -------KDILTPLRDHYSLAEVARRHG------ISADRPTEIEAAFFPEVQMSRSFSD-VFLMI 108

  Fly   200 RNSLLHMWVDNPKIQLSFEIALKNLPPPFDSEPSLVRRVHSFLERHGFINFGIFKRLKPIPAKKL 264
            ||:.|.:|:.:...:.:.|..:|:|.||:::|..||:.:..||.|.|.||.|.|     .|..:|
 Worm   109 RNTTLSIWLASATTECTAEDVIKHLTPPYNTEIHLVQNIVLFLSRFGMINIGFF-----FPKTEL 168

  Fly   265 GK------VIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRI-STFRKNSYIADVGAMVVTG 322
            ..      |:|||||.:|:|.|.||..||.||.|:||....|||: |...|:..:.:.|...:..
 Worm   169 VNNMEKKFVVVIGAGAAGIAAATQLLTFGFDVAVVEASGLTGGRVRSLISKHGELIETGCDSLRN 233

  Fly   323 VYGNPMTILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLESASYLSHRLDFNYA 387
            :..:.:|.|..|:.::...:.:...::. .||.||..:..||...:..|....::.||..:....
 Worm   234 LDESVITTLLHQVPLNENIMSENTIVFS-KGKYVPVARCHVINGLYANLKAGLAHASHGPEQRGE 297

  Fly   388 GDCPVSLGDALEWIISMQEMQV-------------MHKRGQHMQEIIATQTKIIEQRRRLKTLRD 439
            ....:|...|.|...:|.|...             ::...:|:.|::.|
 Worm   298 NGLYISRQQAYENYFNMIERSTLLSYYNFAKEKVNLNAERKHLYEVLKT---------------- 346

  Fly   440 TIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAKLHEL 504
                  |...|::.::|.|.|...     .|..:::.||.:|:.|..|.:.....:....::.:|
 Worm   347 ------NRLTALLAEQKLKNTPPS-----DELLLKSLQIDIEKAIRQFDEACERFEICEERIADL 400

  Fly   505 EQN-------RPSDV----YLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHT 558
            |:|       .|:|.    :|...:..:.......::|  :..:|.|.||           ....
 Worm   401 EKNPRCKQSMHPNDFIHYNFLLGFEERLFGAQLEKVQF--SCNVNELKLK-----------SQVA 452

  Fly   559 TVRNGYS--CVPVALTENLDIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLG 621
            .|:.|.:  .:.||....:.|..|..|.||..|:... |:.:..|...|.....||.||.||.:|
 Worm   453 RVQEGLAQVLINVANERKVKIHHNQRVIEIDTGSSDA-VILKLRKPDGSVGILNADYVVSTLPIG 516

  Fly   622 VLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVGSTT 686
            |||..:...|    ....|.||||..|..||:.||.|.:||:|..|:..||..:.|.|..|....
 Worm   517 VLKKTIIGDE----RAPVFRPPLPKSKFAAIRSLGNGLINKIVFVFETRFWPESINQFAIVPDKI 577

  Fly   687 ASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTR 751
            :.|..||.:.|:..|..|.....|........||:  :|.:.:.:||.:|  ...|.|.:..||.
 Worm   578 SERAAMFTWSSLPESRTLTTHYVGENRFHDTPVTE--LITKALEMLKTVF--KDCPSPIDAYVTN 638

  Fly   752 WRSDPWARGSYSYVSVGSSGSDYDLLAAPVIPPSSKDAEGLPRLFFAGEHTIRNYPATVHGAYLS 816
            |.:|..|.|:.:::|:.:....:|.|..|:     |..:|.||:|||||||......|:.||:.|
 Worm   639 WHTDELAFGTGTFMSLRTEPQHFDALKEPL-----KTRDGKPRVFFAGEHTSALEHGTLDGAFNS 698

  Fly   817 GLREAGRIADYYLGYP 832
            |||.|..:|:..:..|
 Worm   699 GLRAAADLANTCIEIP 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	PLN03000	74..>827	CDD:178578	201/789 (25%)
lsd-1	NP_510000.2	SWIRM	80..158	CDD:461307	26/78 (33%)
		Amino_oxidase	191..706	CDD:396255	145/569 (25%)