Protein Alignment Su(var)3-3 and lsd-1

DIOPT Version :9

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_510000.2
• Gene: lsd-1 / 181369
• WormBaseID: WBGene00011615
• Length: 737
• Species: Caenorhabditis elegans
• Alignment Length: 796
• Identity: 202/796 - (25%)
• Similarity: 331/796 - (41%)
• Gaps: 142/796 - (17%)

  Fly    89 SGDTASNDKSGSAS--------------MGPNNQQAERRSQSQTRKSEANATSSSVSGPSAGNSR 139
            :.|.:.:...||:|              :|..|::.:          ::|..:...|.|
 Worm     9 ANDDSQSSSEGSSSTTPQFIPQVPFDFNLGSINEEVD----------DSNGLTGIASVP------ 57

  Fly   140 PSQNGDSKD-----RDAGTPTVLSGQEGAVFQSRLPFNKMTPNEEACFPDISRSGILGHRVFLNI 199
                   ||     ||..:...::.:.|      :..::.|..|.|.||::..|..... |||.|
 Worm    58 -------KDILTPLRDHYSLAEVARRHG------ISADRPTEIEAAFFPEVQMSRSFSD-VFLMI 108

  Fly   200 RNSLLHMWVDNPKIQLSFEIALKNLPPPFDSEPSLVRRVHSFLERHGFINFGIFKRLKPIPAKKL 264
            ||:.|.:|:.:...:.:.|..:|:|.||:::|..||:.:..||.|.|.||.|.|     .|..:|
 Worm   109 RNTTLSIWLASATTECTAEDVIKHLTPPYNTEIHLVQNIVLFLSRFGMINIGFF-----FPKTEL 168

  Fly   265 GK------VIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRI-STFRKNSYIADVGAMVVTG 322
            ..      |:|||||.:|:|.|.||..||.||.|:||....|||: |...|:..:.:.|...:..
 Worm   169 VNNMEKKFVVVIGAGAAGIAAATQLLTFGFDVAVVEASGLTGGRVRSLISKHGELIETGCDSLRN 233

  Fly   323 VYGNPMTILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLESASYLSHRLDFNYA 387
            :..:.:|.|..|:.::...:.:...::. .||.||..:..||...:..|....::.||..:....
 Worm   234 LDESVITTLLHQVPLNENIMSENTIVFS-KGKYVPVARCHVINGLYANLKAGLAHASHGPEQRGE 297

  Fly   388 GDCPVSLGDALEWIISMQEMQV-------------MHKRGQHMQEIIATQTKIIEQRRRLKTLRD 439
            ....:|...|.|...:|.|...             ::...:|:.|::.|
 Worm   298 NGLYISRQQAYENYFNMIERSTLLSYYNFAKEKVNLNAERKHLYEVLKT---------------- 346

  Fly   440 TIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAKLHEL 504
                  |...|::.::|.|.|...     .|..:::.||.:|:.|..|.:.....:....::.:|
 Worm   347 ------NRLTALLAEQKLKNTPPS-----DELLLKSLQIDIEKAIRQFDEACERFEICEERIADL 400

  Fly   505 EQN-------RPSDV----YLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHT 558
            |:|       .|:|.    :|...:..:.......::|  :..:|.|.||           ....
 Worm   401 EKNPRCKQSMHPNDFIHYNFLLGFEERLFGAQLEKVQF--SCNVNELKLK-----------SQVA 452

  Fly   559 TVRNGYS--CVPVALTENLDIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLG 621
            .|:.|.:  .:.||....:.|..|..|.||..|:... |:.:..|...|.....||.||.||.:|
 Worm   453 RVQEGLAQVLINVANERKVKIHHNQRVIEIDTGSSDA-VILKLRKPDGSVGILNADYVVSTLPIG 516

  Fly   622 VLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVGSTT 686
            |||..:...|    ....|.||||..|..||:.||.|.:||:|..|:..||..:.|.|..|....
 Worm   517 VLKKTIIGDE----RAPVFRPPLPKSKFAAIRSLGNGLINKIVFVFETRFWPESINQFAIVPDKI 577

  Fly   687 ASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTR 751
            :.|..||.:.|:..|..|.....|........||:  :|.:.:.:||.:|  ...|.|.:..||.
 Worm   578 SERAAMFTWSSLPESRTLTTHYVGENRFHDTPVTE--LITKALEMLKTVF--KDCPSPIDAYVTN 638

  Fly   752 WRSDPWARGSYSYVSVGSSGSDYDLLAAPVIPPSSKDAEGLPRLFFAGEHTIRNYPATVHGAYLS 816
            |.:|..|.|:.:::|:.:....:|.|..|:     |..:|.||:|||||||......|:.||:.|
 Worm   639 WHTDELAFGTGTFMSLRTEPQHFDALKEPL-----KTRDGKPRVFFAGEHTSALEHGTLDGAFNS 698

  Fly   817 GLREAGRIADYYLGYP 832
            |||.|..:|:..:..|
 Worm   699 GLRAAADLANTCIEIP 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	SWIRM	165..250	CDD:282311	27/84 (32%)
		NAD_binding_8	269..327	CDD:290186	23/58 (40%)
		Amino_oxidase	274..824	CDD:279874	148/576 (26%)
lsd-1	NP_510000.2	SWIRM	80..158	CDD:367940	26/78 (33%)
		Amino_oxidase	191..706	CDD:366721	145/569 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161020
Domainoid	1	1.000	51	1.000	Domainoid score	I7755
eggNOG	1	0.900	-	-		E1_COG1231
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32240
Inparanoid	1	1.050	248	1.000	Inparanoid score	I2024
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52579
OrthoDB	1	1.010	-	-		D1034142at2759
OrthoFinder	1	1.000	-	-		FOG0001117
OrthoInspector	1	1.000	-	-		otm14062
orthoMCL	1	0.900	-	-		OOG6_103427
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.710