Protein Alignment Su(var)3-3 and amx-1

DIOPT Version :10

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_497772.2
• Gene: amx-1 / 175493
• WormBaseID: WBGene00000137
• Length: 824
• Species: Caenorhabditis elegans
• Alignment Length: 689
• Identity: 189/689 - (27%)
• Similarity: 299/689 - (43%)
• Gaps: 173/689 - (25%)

  Fly   174 MTPNEEACFPDISRSGILGHRVFLNIRNSLLHMWVDNPKIQLSFEIALKNLPPPFDSEPSLVRRV 238
            |..:|:..||..:...|..:  :|.:||:::.||:.:|.::|:.::.          ||.::.|.
 Worm   259 METDEKFAFPKFADDPISIY--YLQVRNTIIAMWLKHPFVELTVKMI----------EPQIIVRG 311

  Fly   239 HS--------------FLERHGFINFGIFK-RLKPIPAKKLGKVIVIGAGISGLAVAHQLQQFGM 288
            |:              ||...|.:|:|.|. |:.|:...: .|:.:|||||||::.|..|:..|:
 Worm   312 HARIFFIEHLIHPILEFLTIKGVVNYGAFDFRIDPLNGMR-PKIAIIGAGISGISTARHLKHLGI 375

  Fly   289 DVIVLEARDRVGGRISTFRKNSYIADVGAMVVTGVYGNPMTILSKQIGMDLVPIQQTCPLYGPDG 353
            |.::.||:||.|||:...:........||.::.|...||:|:|.:|||:........|||...:|
 Worm   376 DAVLFEAKDRFGGRMMDDQSLGVSVGKGAQIIVGNINNPITLLCEQIGIKYRNSNFFCPLIDENG 440

  Fly   354 KPVP---KEKDDVIEREFNRLLESA--SYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHKR 413
            :...   ||.||.::..:|.:|::.  .|.|.|   |:. |.|               ::|.:.|
 Worm   441 RCFTLERKELDDQVDLHYNNVLDAIRNKYQSDR---NFP-DVP---------------LEVTNFR 486

  Fly   414 GQHMQEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQI 478
              |..|:.:
 Worm   487 --HFTEMFS-------------------------------------------------------- 493

  Fly   479 KMEETISTFHDLHAEEKQMLAKLHELEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLK 543
            ||...:.:..||                   ..:|....::| ||:|..||||:..|.::|||.|
 Worm   494 KMSSGLLSAADL-------------------DSLYTPEFEKL-LDFHLGNLEFSCGTHVSNLSAK 538

  Fly   544 HWDQDDDF-EFIGHHTTVRNGYSCVPVALTENLDIRVNSAVKEIKYG--TKGVEVVAENLKTSNS 605
            .:|.::.| .|.|.|..:.:|...:...|...||||:|..||.|.:|  .:.|::..||.:
 Worm   539 DYDHNEKFGNFAGEHAVITDGAQRIIDFLATGLDIRLNCPVKCIDWGRDDRKVKIFFENAE---- 599

  Fly   606 QMTYKADLVVCTLTLGVLKVAVAHKESQQSNTVK-FDPPLPDWKQQAIKRLGFGNLNKVVLCFDR 669
            |...:.|.||.|.:|.|||          ||..| |.||||..||:||..||.|.:.|:.:.|||
 Worm   600 QAAEEFDKVVITTSLSVLK----------SNHSKMFVPPLPIEKQKAIDDLGAGLIEKIAVKFDR 654

  Fly   670 IFWDP------NANLFGHVGSTTASRGEMFLFWSISSSP-------VLLALVAGMAANLVESVTD 721
            .|||.      ....||.|......|....:|:..|...       ||::.|.....|||..:|:
 Worm   655 RFWDTVDADGLRTEYFGKVSDCKTDRSLFNIFYDFSGKDPNGEDTFVLMSYVTAEHVNLVNVLTE 719

  Fly   722 DIIIGRCMSVLKNIFGNTSVPQPKETVVTRWRSDPWARGSYSYVSVGSSG-SDYDLLAAPVIPPS 785
            ..:..:..:.|:.:| .::|..|...:::.|.:|.:...||::|..||.| :.|:.|...:.
 Worm   720 SEVADKFCATLRKMF-PSAVINPLGHMMSHWGADRFVGMSYTFVPFGSDGDATYNQLKKSID--- 780

  Fly   786 SKDAEGLPRLFFAGEHTIRNYPATVHGAYLSGLREAGRI 824
                   .:|:|||||||...|.|:.|||:|||||||:|
 Worm   781 -------EKLYFAGEHTIAAEPQTMAGAYISGLREAGQI 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	PLN03000	74..>827	CDD:178578	189/689 (27%)
amx-1	NP_497772.2	SWIRM	254..337	CDD:461307	19/89 (21%)
		Amino_oxidase	361..812	CDD:396255	159/572 (28%)