Protein Alignment Su(var)3-3 and spr-5

DIOPT Version :10

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_493366.1
• Gene: spr-5 / 173214
• WormBaseID: WBGene00005010
• Length: 770
• Species: Caenorhabditis elegans
• Alignment Length: 832
• Identity: 224/832 - (26%)
• Similarity: 363/832 - (43%)
• Gaps: 165/832 - (19%)

  Fly   139 RPSQNGDSKDRDAGTPTVLSGQEGAVFQSRLPFNKMTPNEEACFPDI--SRSGILGHRVFLNIRN 201
            |..:.|.|.|.:|        ...|...:||||::.|.:|.|.||::  .::.:   .|||.:||
 Worm    15 RGDELGPSIDDNA--------LAAAASAARLPFDRPTDHELAFFPELWEHKTAV---EVFLLLRN 68

  Fly   202 SLLHMWVDNPKIQLSFEIALKNLPPPFDSEPSLVRRVHSFLERHGFINFGIFKRLKPIP---AKK 263
            |.|..|..||..:.:......|:.|||:|:..|::.:..:|.|||.||||.:.|...|.   .:.
 Worm    69 STLATWQYNPLKECTALDVRNNVFPPFNSDLDLIQNIVHYLSRHGLINFGRYVRSTKISRFLVRD 133

  Fly   264 LGKVIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFR-KNSYIADVGAMVVTGVYGNP 327
            ...|||||||.:|::.|.||:.||.||||||||:.:||||.:|: |:..|.:.|...:..:..:|
 Worm   134 RRSVIVIGAGAAGISAATQLESFGFDVIVLEARNCIGGRIHSFKSKSGEIMETGGDTLRKIEDSP 198

  Fly   328 MTILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLESASYLSHRLDFNYAGDCPV 392
            |..|..|:..:...:.....:: .:|:|:.:||..:....:.....:.:|.:|:.:........:
 Worm   199 MATLLHQVNFEEHGVFDFTSVF-VEGRPLNEEKIHLFLDHYKSAHGALNYQAHQCEHRDDQGSFI 262

  Fly   393 SLGDALEWIISMQEMQVMHKRGQHMQEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMINQRKP 457
            |...|.|.::||.|      ||           .:|:.....|:| :|:.:.:..|...:.|.:.
 Worm   263 SRQQAYENLLSMCE------RG-----------TLIKYYNFCKSL-ETVARAREHHFNQMKQLRM 309

  Fly   458 KG--TDGDLKYCYQEFNIRNTQI--------------KMEETISTFH---------DLHAEEKQM 497
            ..  .:..||...:|.|:....:              |.||....|.         :.|.:.||.
 Worm   310 TALMAENQLKKMEEEGNLEQDPVLRRSLKRDIATSLEKFEEVADAFETADNHWQRLNEHPQAKQY 374

  Fly   498 L---------------------AKLHELE------QNRPSDVYLSSRDRLILDWHFANLEFANAT 535
            :                     |:|.:::      ||:.:.|             .|.|....|.
 Worm   375 MHPGSEFATFNFMLGFEEYLVGAQLEKVQFSCDSMQNKENGV-------------AARLTEGIAE 426

  Fly   536 RLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVPVALTENLDIRVNSAVKEIKYGTKGVEVVAENL 600
            .|..||.|                             ..||||:...|.:|.|  .|.|.|...:
 Worm   427 LLTQLSEK-----------------------------RKLDIRLKHRVLDIDY--SGFEHVLLKV 460

  Fly   601 KTSNSQM-TYKADLVVCTLTLGVLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVV 664
            :..|..: ..||..||.||.:||||..:...|...:    |.|.|||.|.:||:.:|.|::||.:
 Worm   461 QRENGDIEEMKAAFVVSTLPIGVLKKTIIADERAPT----FTPSLPDKKVEAIRNIGCGSVNKCI 521

  Fly   665 LCFDRIFWDPNA--NLFGHVGSTTASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGR 727
            |.|||:||..|.  |.|..|.....:||.|.::.|:..|.||...:.|..|.|  .:.||:||..
 Worm   522 LEFDRVFWTANGGRNQFVTVSPNIKTRGSMNIWSSVPGSKVLCTYIVGEEAML--ELPDDVIIQN 584

  Fly   728 CMSVLKNIFGNTSVPQPKETVVTRWRSDPWARGSYSYVSVGSSGSDYDLLAAPVIPPSSKDAEGL 792
            .|..|:..|||.....|....:|||..|..|.||.:::|:.:..:.:|.:..|:     |.::|:
 Worm   585 AMINLQKAFGNNCPRAPISAHITRWHDDELAFGSGAFMSLRTETTSFDDVMEPL-----KTSDGM 644

  Fly   793 PRLFFAGEHTIRNYPATVHGAYLSGLREAGRIADYYLGYP----EGTPPDIGYSVAEAANLVSVG 853
            .|::||||||..:|.:|:.||::||.|.|..|::.::|..    .||....|....|....|.:.
 Worm   645 SRVYFAGEHTCSSYTSTIQGAWMSGARAAADISNDHIGIGFVDISGTRGQRGDEEEELLIEVDID 709

  Fly   854 NVVKLRDLSPNLSD-----SSPSSKKSEE----------NSNSNTADSTELQ 890
            ..:..:|.:..::|     ::|:::|.||          .:.:..|:..|:|
 Worm   710 GKIPEKDENEAVADIPNAPNAPNAQKPEEIPKIAEEIELVAEAEKAEKAEVQ 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	PLN03000	74..>827	CDD:178578	209/748 (28%)
spr-5	NP_493366.1	SWIRM	39..117	CDD:461307	27/80 (34%)
		Amino_oxidase	151..676	CDD:396255	158/598 (26%)