Protein Alignment Su(var)3-3 and Maoa

DIOPT Version :9

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: NP_776101.3
• Gene: Maoa / 17161
• MGIID: 96915
• Length: 526
• Species: Mus musculus
• Alignment Length: 653
• Identity: 133/653 - (20%)
• Similarity: 225/653 - (34%)
• Gaps: 189/653 - (28%)

  Fly   257 KPIPAKKLGKVIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFRKNSYI--ADVGAMV 319
            ||.....:..|:|||.||||||.|..|.::.::|:|||||||||||..|.| |.::  .|||...
Mouse     6 KPSITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVR-NEHVKWVDVGGAY 69

  Fly   320 VTGVYGNPMTILSKQIGMDLVPIQ-----------QTCPLYGPDGKPVPKEKDDVIEREFNRLLE 373
            | |...|.:..|||::|::...:.           :|.|..|    ..|...:.:...::|.|..
Mouse    70 V-GPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRG----AFPPVWNPLAYLDYNNLWR 129

  Fly   374 SASYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHKRGQHMQEIIATQTKIIEQRRRLKTLR 438
            :...:...:..    |.|.....|.||                        .||        |::
Mouse   130 TMDDMGKEIPV----DAPWQARHAEEW------------------------DKI--------TMK 158

  Fly   439 DTIGKLKNEHLAMINQRKPKGTDGDLKYCYQEFNIRNTQIKMEETISTFHDLHAEEKQMLAKLHE 503
            |.|.|:             ..|....::.|...||..|        |..|::.|
Mouse   159 DLIDKI-------------CWTKTAREFAYLFVNINVT--------SEPHEVSA----------- 191

  Fly   504 LEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVP 568
                            |...|:..  :....:|:  .|:.:..|:.  :|:|....:...   :.
Mouse   192 ----------------LWFLWYVR--QCGGTSRI--FSVTNGGQER--KFVGGSGQISEQ---IM 231

  Fly   569 VALTENLDIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLGVLKVAVAHKESQ 633
            |.|.:.  ::::|.|..|.....  .::.|.|...:.:..|....:...||.
Mouse   232 VLLGDK--VKLSSPVTYIDQTDD--NIIIETLNHEHYECKYVISAIPPVLTA------------- 279

  Fly   634 QSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFW------------DPNANLFGHVGSTT 686
               .:.|.|.||..:.|.|:||..|.:.|.::.:...||            |..|.:...:..|.
Mouse   280 ---KIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTK 341

  Fly   687 ASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTR 751
            ..          .|.|.::..:....|..:..:..||...:...:...:.|:.....|.......
Mouse   342 PD----------GSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSQEALSPVHYEEKN 396

  Fly   752 WRSDPWARGSYSYVSVGSSGSDYDLLAAPVIPPSSKDAEG------LPRLFFAGEHTIRNYPATV 810
            |..:.::.|.|:                ...||......|      :.|::|||..|...:...:
Mouse   397 WCEEQYSGGCYT----------------AYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYM 445

  Fly   811 HGAYLSGLREA-------GRIA--DYYLGYPEG--TPP-DIGYSVAEAANLVSVGNVVKLRDLSP 863
            .||..:|.|.|       |::|  |.::..||.  .|. :|.::..| .||.||..::|:...|.
Mouse   446 EGAVEAGERAAREVLNALGKVAKKDIWVQEPESKDVPALEITHTFLE-RNLPSVPGLLKITGFST 509

  Fly   864 NLS 866
            :::
Mouse   510 SVA 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	SWIRM	165..250	CDD:282311
		NAD_binding_8	269..327	CDD:290186	31/59 (53%)
		Amino_oxidase	274..824	CDD:279874	113/587 (19%)
Maoa	NP_776101.3	YobN	15..463	CDD:224152	117/592 (20%)
		NAD_binding_8	18..84	CDD:290186	35/67 (52%)
		Interaction with membrane phospholipid headgroups. /evidence=ECO:0000250	520..522

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1231
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1034142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820