Protein Alignment Su(var)3-3 and Su(var)3-3

DIOPT Version :10

• Sequence 1: NP_649194.1
• Gene: Su(var)3-3 / 40217
• FlyBaseID: FBgn0260397
• Length: 890
• Species: Drosophila melanogaster
• Sequence 2: XP_061518943.1
• Gene: Su(var)3-3 / 1280978
• VectorBaseID: AGAMI1_011244
• Length: 886
• Species: Anopheles gambiae
• Alignment Length: 909
• Identity: 512/909 - (56%)
• Similarity: 619/909 - (68%)
• Gaps: 140/909 - (15%)

  Fly    15 EPIEYVTLISDDSDGEPTPKRNVNHPPSALSAPNPGQKQKHPDEDSNDAPATSDE-RRTSRRNRP 78
            ||:|.|||||||||.|.|.          :|...|.:.:             ||| ||||||.:.
Mosquito    21 EPVETVTLISDDSDVEMTD----------ISVKRPSKSE-------------SDEGRRTSRRKKV 62

  Fly    79 KVDYSNRPSGSGDTASNDKSGSASMGPNNQQAERRSQSQTRKSEANAT---------SSSVSGPS 134
            ||.|.:  :|:....|..:.|||....:......|....|.|::|..|         ..|.:||
Mosquito    63 KVGYGD--NGAKTNTSTARPGSACERGDGVITPDRKAETTTKADAPPTPKSKKREVEEKSATGP- 124

  Fly   135 AGNSRPSQNGDSKDRDAGTPTVLSGQEGAVFQSRLPFNKMTPNEEACFPDISRSGILGHRVFLNI 199
              :..|.|.            :::|.|||.||||||.:|||.:|..|||.|.:.|::..|||||:
Mosquito   125 --DPNPYQE------------LMTGLEGAAFQSRLPVDKMTASEAVCFPHIIKHGLVAQRVFLNV 175

  Fly   200 RNSLLHMWVDNPKIQLSFEIALKNLPPPFDSEPSLVRRVHSFLERHGFINFGIFKRLKPIPAKKL 264
            ||.:|.||::.|.:||:.|.|||.:..||||:|||||.||:||||||||||||||||.|:|.||.
Mosquito   176 RNRILQMWIEEPTVQLTVENALKKMESPFDSDPSLVRSVHAFLERHGFINFGIFKRLIPLPVKKH 240

  Fly   265 GKVIVIGAGISGLAVAHQLQQFGMDVIVLEARDRVGGRISTFRKNSYIADVGAMVVTGVYGNPMT 329
            .|||||||||||||.|.||||||.|||||||||||||||:|||||:|.||:|||||||.:|||:|
Mosquito   241 AKVIVIGAGISGLAAAQQLQQFGFDVIVLEARDRVGGRIATFRKNAYTADLGAMVVTGTWGNPLT 305

  Fly   330 ILSKQIGMDLVPIQQTCPLYGPDGKPVPKEKDDVIEREFNRLLESASYLSHRLDFNYAGDCPVSL 394
            |||||.||::.||:..|||||..||||||.|||::|||||||||:.|||||:|||||||:.||||
Mosquito   306 ILSKQTGMEMCPIKSVCPLYGAGGKPVPKHKDDMVEREFNRLLEATSYLSHQLDFNYAGNHPVSL 370

  Fly   395 GDALEWIISMQEMQVMHKRGQHM-------QEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMI 452
            |.||||||.:||..|..|:.||:       |:::|.|.:::|...|::.|     |.|.:||  |
Mosquito   371 GQALEWIIKLQEKHVKEKQVQHLGGIIGCQQKLLANQQQLVETLARIRDL-----KAKQQHL--I 428

  Fly   453 NQRKPK----------------GTDGD---------LKYCYQEFNI----RNTQIKMEETISTFH 488
            :.:.||                ||.|.         .||...||.:    |..|:..:|.    .
Mosquito   429 DTKPPKPPPPAKEGGSGGGGGGGTAGQDTSGGDSAGTKYFEHEFQLRVMAREEQLAWKEV----E 489

  Fly   489 DLHAEEKQMLAKLHELEQNRPSDVYLSSRDRLILDWHFANLEFANATRLNNLSLKHWDQDDDFEF 553
            .|.|.:.::.||:.|||..:.|:|||||:||.|||||||||||||||.|:|||||||||||||||
Mosquito   490 RLQAYQTELEAKVRELENEQVSEVYLSSKDRQILDWHFANLEFANATPLSNLSLKHWDQDDDFEF 554

  Fly   554 IGHHTTVRNGYSCVPVALTENLDIRVNSAVKEIKYGTKGVEVVAENLKTSNSQMTYKADLVVCTL 618
            ||.||||:|||||||:|||||||:|||:||..|:|...||||.|: ||::||.:.|:||||:|||
Mosquito   555 IGSHTTVKNGYSCVPIALTENLDVRVNTAVTCIRYRPGGVEVTAD-LKSNNSTVCYRADLVLCTL 618

  Fly   619 TLGVLKVAVAHKESQQSNTVKFDPPLPDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVG 683
            |||:||:|:| |||:|.|||:|||.||:|||.||:||||||||||||||||||||||.|||||||
Mosquito   619 TLGILKLAIA-KESKQLNTVRFDPELPEWKQLAIRRLGFGNLNKVVLCFDRIFWDPNTNLFGHVG 682

  Fly   684 STTASRGEMFLFWSISSSPVLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETV 748
            ||||||||:||||:||.||||||||||.:|.::|:|:||:|:|||::|||.||||::||||||||
Mosquito   683 STTASRGELFLFWNISQSPVLLALVAGQSAAIMENVSDDVIVGRCIAVLKGIFGNSAVPQPKETV 747

  Fly   749 VTRWRSDPWARGSYSYVSVGSSGSDYDLLAAPVIPPS---------------------------- 785
            |||||:|||||||||:||||:||||||||||||.|.:
Mosquito   748 VTRWRADPWARGSYSFVSVGASGSDYDLLAAPVTPKAPEGAKPPPPPQKPPTAPQQQQQQQRHDK 812

  Fly   786 ---SKDAE----------GLPRLFFAGEHTIRNYPATVHGAYLSGLREAGRIADYYLGYPEGTP 836
               .||.|          .:|||||||||||||||||||||.||||||||||||||||:|...|
Mosquito   813 NGDKKDNEENDDEDSNPIDIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADYYLGFPNCYP 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)3-3	NP_649194.1	PLN03000	74..>827	CDD:178578	482/838 (58%)
Su(var)3-3	XP_061518943.1	None