DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7017 and CG4835

DIOPT Version :9

Sequence 1:	NP_001262095.1	Gene:	CG7017 / 40213	FlyBaseID:	FBgn0036951	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_647965.3	Gene:	CG4835 / 38619	FlyBaseID:	FBgn0035607	Length:	1224	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	86/466 - (18%)
Similarity:	143/466 - (30%)	Gaps:	164/466 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GVIEDFEYLSVAEMCDLLPQETSFLR-PNTCDNWVRCASNYSVLEQGGCAAGLNYNKELGRC--- 79
            |:.||:        |  :|:...|.. |..|..::.|.:..:.|:.  |.....:|..|..|
  Fly   267 GIEEDY--------C--VPKGNGFYEYPYNCSGYLACKNGCTDLDY--CQPDKLFNNWLHICDTP 319

  Fly    80 -------------------------------------------------ILASSSAAVCPYADSI 95
                                                             |.:|::..:....|.:
  Fly   320 DSVRCDPLPFPTTPGTTNKPTTPSVTTTPSITTTPSTPTTLPSDGSTTEIHSSTTEEIVTTTDGL 384

  Fly    96 -ADKATNLCANETEG---AFIVDPSSSDCRGYILCKSHKQIKANCPNELIFHPVSRSCVYEKQYR 156
             :|...|.|.:|.:|   |:|     .:|..|::||.::....:||...:|:|....|.......
  Fly   385 PSDVDPNDCKDEKDGTIFAYI-----GNCSEYLICKDNQVQMGHCPPNTLFNPDLLVCDEPDDVV 444

  Fly   157 C-------------PISQTKKTSPACRSLPNNTRLAD---------------PVHCDQYYECVSE 193
            |             |.:.|:||:|...:....|.|..               |..|.:||.|:..
  Fly   445 CLGDRTTTPIPTTIPTTTTEKTTPTTTTTTVATTLGPDQLCDGQELGASFSYPDDCSKYYLCLGG 509

  Fly   194 VLHSRA-CPVASAYDANLGYC-VDVAEVSCY------------------------ESAALPEPEN 232
            ...:.| |...|.:|.:.|.| .|||..:|.                        :|.|......
  Fly   510 GQWTLAPCIYGSYFDPSTGQCGPDVAPDACKPSQVTTTTTTTTTETTTTERNTTPKSTATTTERT 574

  Fly   233 TFCLDSATG-------SARVGYFADDESCSHYYICGSPVAGKHDTEPKHLSCPLGQYFDFEKLSC 290
            |..:...||       :..:.|   ..:|:.|.:|.||:       |....||.|.:|..:...|
  Fly   575 TTTVAPKTGICGGRNENENIAY---PNNCTKYIVCVSPI-------PIAFFCPDGTFFSSKLEKC 629

  Fly   291 RDRLNVR-CQLDR------------------CVGTNITYVNVAGDCQSYGRCSGGVTVSLGQCPT 336
            .|..:.. |:.|:                  |..::........:||.:.||.......:..|..
  Fly   630 IDDWDESDCEGDQSTTTLEPGYTRPPPEPTMCTNSSRDTFPYPDNCQWFIRCVDDYIYMMDVCNC 694

  Fly   337 GYYFDERNQGC 347
            |.|:|...:.|
  Fly   695 GEYYDPITEKC 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7017	NP_001262095.1	CBM_14	103..155	CDD:279884	14/54 (26%)
		ChtBD2	246..290	CDD:214696	11/43 (26%)
		CBM_14	303..348	CDD:279884	10/45 (22%)
CG4835	NP_647965.3	CBM_14	51..103	CDD:279884
		CBM_14	185..237	CDD:279884
		CBM_14	273..322	CDD:279884	11/52 (21%)
		CBM_14	393..444	CDD:279884	14/55 (25%)
		CBM_14	485..539	CDD:279884	14/53 (26%)
		CBM_14	585..638	CDD:279884	13/62 (21%)
		CBM_14	661..714	CDD:279884	10/45 (22%)
		CBM_14	744..796	CDD:279884
		CBM_14	914..962	CDD:279884
		CBM_14	1175..1212	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950