DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6996 and Tnxb

DIOPT Version :9

Sequence 1:	NP_001262094.1	Gene:	CG6996 / 40212	FlyBaseID:	FBgn0036950	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_006525248.1	Gene:	Tnxb / 81877	MGIID:	1932137	Length:	4361	Species:	Mus musculus

Alignment Length:	364	Identity:	88/364 - (24%)
Similarity:	125/364 - (34%)	Gaps:	107/364 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NATLICSLVVNGTK---MNDPRACNAWIQCIDGSPVSGSCATGLFYDRES---QKCL--SSSSIK 80
            |...:|:...:|..   .|.||.|:...:|.||..|   |..|  |..|.   :.|.  .....:
Mouse   279 NGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCV---CDPG--YSGEDCSMRTCPWDCGDGGR 338

  Fly    81 CLSSDPCAALPTGFAAD-------PYSCNGYYYCKDGKGTHGVCNTGMNFNSGTQDC-IRDFP-- 135
            |:.. .|...| |::.:       |..|.|...|:||:   .:|:.|.   || .|| :|..|
Mouse   339 CVDG-RCVCWP-GYSGEDCSTRTCPRDCRGRGRCEDGE---CICDAGY---SG-DDCGVRSCPGD 394

  Fly   136 CSNKMD-PDSYCNILPDGVFVKDTD------NCNGYQLCWDGQVI-----NG------TCPGTFY 182
            |:.:.. .|..|...| |....|..      :|.|...|.||..:     :|      :|||..
Mouse   395 CNQRGHCEDGRCVCWP-GYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDC- 457

  Fly   183 FKASTAQCDYPQNV--------ECDFVPVPDISKKGVCPETGGFISDNKTCNGYYYCKDLGN--- 236
              .....|:..:.|        :|.....|     |.|...|..:.....||..:..:|.|:
Mouse   458 --RGRGNCESGRCVCWPGYTGRDCGTRACP-----GDCRGRGRCVDGRCVCNPGFTGEDCGSRRC 515

  Fly   237 -----GEFSLEHGVCSDGRFFLATDGGACVPRSKVKCGYDRCVGLGNSTIQLANESDDG------ 290
                 |....|:|||...   :...|..|..||   |..| |.|.|.....|. |.|:|
Mouse   516 PGDCRGHGHCENGVCVCA---VGYSGDDCSTRS---CPSD-CRGRGQCLNGLC-ECDEGYSGEDC 572

  Fly   291 --------CRGYSICQDGIVI------GQG----TCPQD 311
                    |..:.:||||:.:      |:.    |||.|
Mouse   573 GIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPAD 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6996	NP_001262094.1	CBM_14	29..73	CDD:279884	14/49 (29%)
		ChtBD2	85..130	CDD:214696	13/51 (25%)
		CBM_14	146..196	CDD:279884	14/66 (21%)
		CBM_14	273..322	CDD:279884	17/63 (27%)
Tnxb	XP_006525248.1	EGF_2	172..200	CDD:285248
		EGF_2	203..231	CDD:285248
		EGF_Tenascin	236..262	CDD:376143
		EGF_Tenascin	267..293	CDD:376143	3/13 (23%)
		EGF_Tenascin	298..325	CDD:376143	11/31 (35%)
		EGF_Tenascin	329..356	CDD:376143	5/28 (18%)
		EGF_Tenascin	360..386	CDD:376143	10/32 (31%)
		EGF_2	389..417	CDD:285248	7/28 (25%)
		EGF_Tenascin	422..448	CDD:376143	6/25 (24%)
		EGF_2	451..479	CDD:285248	5/30 (17%)
		EGF_2	482..510	CDD:285248	6/32 (19%)
		DSL	<498..541	CDD:366627	10/45 (22%)
		EGF_2	541..572	CDD:285248	12/35 (34%)
		EGF_Tenascin	577..604	CDD:376143	6/26 (23%)
		EGF_2	608..634	CDD:285248	3/4 (75%)
		EGF_Tenascin	639..665	CDD:376143
		EGF_Tenascin	706..732	CDD:376143
		fn3	737..818	CDD:365830
		fn3	830..906	CDD:365830
		fn3	1074..1142	CDD:365830
		fn3	1295..1369	CDD:365830
		FN3	1386..1466	CDD:238020
		fn3	1484..1558	CDD:365830
		fn3	1599..1674	CDD:365830
		fn3	1707..1782	CDD:365830
		fn3	1804..1874	CDD:365830
		fn3	1904..1971	CDD:365830
		fn3	2000..2067	CDD:365830
		fn3	2102..2164	CDD:365830
		FN3	2211..2279	CDD:238020
		fn3	2315..2393	CDD:365830
		fn3	2426..2496	CDD:365830
		fn3	2525..2600	CDD:365830
		fn3	2639..2709	CDD:365830
		fn3	2748..2823	CDD:365830
		fn3	2861..2931	CDD:365830
		fn3	2970..3043	CDD:365830
		fn3	3076..3146	CDD:365830
		fn3	3183..3258	CDD:365830
		fn3	3291..3361	CDD:365830
		fn3	3387..3462	CDD:365830
		fn3	3480..3542	CDD:365830
		fn3	3569..3649	CDD:365830
		fn3	3679..3752	CDD:365830
		fn3	3776..3855	CDD:365830
		fn3	3875..3953	CDD:365830
		FN3	3962..4048	CDD:238020
		fn3	4052..4129	CDD:365830
		Fibrinogen_C	4143..4352	CDD:278572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910