DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6996 and Mur89F

DIOPT Version :9

Sequence 1:	NP_001262094.1	Gene:	CG6996 / 40212	FlyBaseID:	FBgn0036950	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001262662.1	Gene:	Mur89F / 42080	FlyBaseID:	FBgn0038492	Length:	2159	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	87/485 - (17%)
Similarity:	128/485 - (26%)	Gaps:	213/485 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NATLICSLVVNGTKMNDPRACNAWIQCIDG-----SPVSGSCATGLFYDRESQKCLSSSSIK-C- 81
            |.:..|.  |||..:.|...|..:.:|:|.     :.|..||..|..:|.:.|.|..:.::| |
  Fly  1200 NPSETCK--VNGQFIGDRSDCAKFYRCVDNDRGGFNMVPFSCGPGTVWDAQMQACNHAWAVKECG 1262

  Fly    82 -----LSSDPCAALPT------------------------------------------------- 92
                 .:|.|..:.||
  Fly  1263 GIAPPTTSTPTTSRPTTASTSRPSDQTSTSRPTGPPTTARPVTARPTTSSPTTASSSQTTSPVTQ 1327

  Fly    93 -----------GFAADPYSCNGYYYC-KDGKGTHGV------CNTGMNFNSGTQDCIRDF-PCSN 138
                       ||.|||.:|:.:|.| ::.||  |.      |..|..::...|.|..:| .||.
  Fly  1328 APNTDGKCRSEGFMADPNNCSKFYRCVRNNKG--GFTSIPFQCGAGTVWDQDLQTCNHNFNNCST 1390

  Fly   139 KMD---PDSYCNILPDGVFVKDTDNCNGYQLCWDGQVINGTCPGTFYFKASTAQCDYPQNVECDF 200
            ..:   |...|....:|.....|.:..             |.|.|......|:....|.....:.
  Fly  1391 GTESTTPKPPCEPATNGTTATSTSSTT-------------TPPPTTTDLPPTSTTGLPPTTTTEL 1442

  Fly   201 VP-----------------------------VPDISKKGVCPETGGFISDNKT------------ 224
            .|                             :|..:..|..|.|....|:.:|
  Fly  1443 PPTTTTDLPPTTTTRLPPTTTTSLPPTTTTGLPPTTTTGAQPTTTTLSSETETSTVTTSPESTTQ 1507

  Fly   225 ---------------CNGYYYCKDLGNGEFSLEHGVCSDGRFFLATDGGACVPRSKVKCGYDRCV 274
                           |.|..|..|                            |....|  |.||:
  Fly  1508 PPSTTTMKPLPAGTECTGEGYMAD----------------------------PEDCRK--YYRCI 1542

  Fly   275 GLGNSTIQLANESDDGCRGYSICQDGIVIGQGTCPQDEYFDEITQRCTTQVISYTACQISEATTG 339
            ..|.|           .|.|:.          |||:...::|..|.| ..|.:...|....|...
  Fly  1543 NAGAS-----------YRKYNF----------TCPKGTGWNEEVQTC-DYVENIPRCSKLPAEPI 1585

  Fly   340 SQVPSGT-----TTTTSSTITSTTIAVPVS 364
            :..||..     :||..||...||:..|::
  Fly  1586 TTTPSEESKDPGSTTPQSTDEPTTVTKPIT 1615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6996	NP_001262094.1	CBM_14	29..73	CDD:279884	14/48 (29%)
		ChtBD2	85..130	CDD:214696	17/111 (15%)
		CBM_14	146..196	CDD:279884	8/49 (16%)
		CBM_14	273..322	CDD:279884	10/48 (21%)
Mur89F	NP_001262662.1	CBM_14	57..106	CDD:279884
		CBM_14	200..250	CDD:279884
		CBM_14	484..536	CDD:279884
		CBM_14	745..798	CDD:279884
		CBM_14	1025..1074	CDD:279884
		CBM_14	1206..1261	CDD:279884	15/56 (27%)
		CBM_14	1336..1388	CDD:279884	16/53 (30%)
		CBM_14	1523..1577	CDD:279884	20/105 (19%)
		VAD1-2	<1599..>1656	CDD:291956	7/17 (41%)
		CBM_14	1809..1861	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100