DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7290 and CG4835

DIOPT Version :9

Sequence 1:	NP_001262093.1	Gene:	CG7290 / 40211	FlyBaseID:	FBgn0036949	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_647965.3	Gene:	CG4835 / 38619	FlyBaseID:	FBgn0035607	Length:	1224	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	114/506 - (22%)
Similarity:	180/506 - (35%)	Gaps:	122/506 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PAIADVNVTALCLLVSNGNYVASQSDCSTYYQCQGSSFTAMSCPQGYYF---------------- 69
            |:..|.|.   |....:|...|...:||.|..|:.:......||....|
  Fly   385 PSDVDPND---CKDEKDGTIFAYIGNCSEYLICKDNQVQMGHCPPNTLFNPDLLVCDEPDDVVCL 446

  Fly    70 -DKNAQQCTGTVPSTCTSNSDP----------------CLGKAVGSFAASSSSCGGYYYC-GASG 116
             |:.......|:|:|.|..:.|                |.|:.:|:..:....|..||.| |...
  Fly   447 GDRTTTPIPTTIPTTTTEKTTPTTTTTTVATTLGPDQLCDGQELGASFSYPDDCSKYYLCLGGGQ 511

  Fly   117 AVRGNCPAGENFNPTTMAC---------------------------VYKNNYPCS-ESAGDGSTV 153
            .....|..|..|:|:|..|                           ..:|..|.| .:..:.:|.
  Fly   512 WTLAPCIYGSYFDPSTGQCGPDVAPDACKPSQVTTTTTTTTTETTTTERNTTPKSTATTTERTTT 576

  Fly   154 SVA--LNLCNLVKNGFYFGSPSDCSGWNFCQDNVLHSGSCEDGLVFNVQASNCGYKM-ASSC--- 212
            :||  ..:|...........|::|:.:..|...:..:..|.||..|:.:...|.... .|.|
  Fly   577 TVAPKTGICGGRNENENIAYPNNCTKYIVCVSPIPIAFFCPDGTFFSSKLEKCIDDWDESDCEGD 641

  Fly   213 -AQVTNDPSLT-GVSAPTTCSSSGATIAATACN-QYYLCSAGNYQLM--TCPSGYYYDTISKACV 272
             :..|.:|..| ....||.|::|.........| |:::....:|..|  .|..|.|||.|::.|.
  Fly   642 QSTTTLEPGYTRPPPEPTMCTNSSRDTFPYPDNCQWFIRCVDDYIYMMDVCNCGEYYDPITEKCG 706

  Fly   273 TRMEARNDCDRC----VGTTATFVNAYSAT-------------------------NCSDYLYCVN 308
            ..:.:    |.|    ..||:|.....:.|                         :||.|:.|..
  Fly   707 ADVPS----DACRWDYTSTTSTTSEPTTTTAVTRPPPQKGPCDDVEDGALVAYPNDCSKYIQCDR 767

  Fly   309 GVQKAVESCPTNYYFNENLGSCVNGLEPKFLCCN------PTQSDGTSTSSSGSTSSGSTSSGST 367
            .:..|.| |.....|:..||.||   :.....|:      |::|..|.....|||:....|:||:
  Fly   768 PIAVAFE-CEKGDEFSVELGKCV---DASLANCSITTTAKPSESTTTPRDGEGSTTPSEPSTGSS 828

  Fly   368 SSGST-SSGSTSSGSTSSGSTSSGSTSSGSTSSGSTSSGTSSTT--STGTS 415
            :..|| |:...|:.||:..:|.|.:.|:..:|:|.::..|.|:|  ||.||
  Fly   829 TESSTESTTEPSTESTTESTTESTTESTTESSTGQSTETTESSTVLSTDTS 879

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7290	NP_001262093.1	CBM_14	32..77	CDD:279884	11/61 (18%)
		CBM_14	91..142	CDD:279884	15/78 (19%)
		CBM_14	160..207	CDD:279884	9/46 (20%)
		CBM_14	234..277	CDD:279884	11/45 (24%)
		ChtBD2	<296..331	CDD:214696	11/59 (19%)
CG4835	NP_647965.3	CBM_14	51..103	CDD:279884
		CBM_14	185..237	CDD:279884
		CBM_14	273..322	CDD:279884
		CBM_14	393..444	CDD:279884	10/50 (20%)
		CBM_14	485..539	CDD:279884	14/53 (26%)
		CBM_14	585..638	CDD:279884	10/52 (19%)
		CBM_14	661..714	CDD:279884	14/56 (25%)
		CBM_14	744..796	CDD:279884	12/55 (22%)
		CBM_14	914..962	CDD:279884
		CBM_14	1175..1212	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950