DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7298 and CG10725

DIOPT Version :9

Sequence 1:	NP_649187.3	Gene:	CG7298 / 40210	FlyBaseID:	FBgn0036948	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_648647.1	Gene:	CG10725 / 39510	FlyBaseID:	FBgn0036362	Length:	269	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	70/295 - (23%)
Similarity:	106/295 - (35%)	Gaps:	56/295 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTGKLLLATILCLMGGQALGDAILEGNYNVTAVCTAVKVGTQLGSIESCQTYYVCQSTGPVQSSC 65
            |..:|.|..::.|:|..:..|    |:.|   ||:.|.....:..:.:|..|::|.:...|...|
  Fly     1 MISRLTLLALVALLGSCSAAD----GDVN---VCSNVVNNLFVPQVGNCSKYFLCMNEIAVPREC 58

  Fly    66 QSGYSYDYKRSSCYPSSEVDCYWGVENPCAGKNNTWVPNTAVCGGWFYCLEGK------------ 118
            .:.|.:|.:...|.|..||:|....:|  .|.::.....|  |..:..|.:|.
  Fly    59 PTDYYFDARDQECVPLMEVECIGSCKN--RGLSSFCYDRT--CTKYVLCFDGTPVIRQCSDGLQY 119

  Fly   119 SAGSGNCPVNQKFDTTTLACVYGTCSNTQGTNETVLESLCDVVPPGQYFGDTESCSTWHYCESTS 183
            :|.:..|...|..|     ||...||.....::.|            :......|..::.|   .
  Fly   120 NALTDRCDYPQYVD-----CVDNLCSRNNNPDDIV------------FIPSKARCDKYYIC---M 164

  Fly   184 TGLVLQSGKCSANNQTAYNVLANQCTYESASVC---SRVTNI------PLSDAAVSCSTNGAK-S 238
            .||. |...|::..|  ||.....|.:.|...|   |...||      |...|.:.|.:.||. .
  Fly   165 DGLP-QVQNCTSGLQ--YNPSTQSCDFPSKVNCTVESLQRNILPFARAPPRLADIECPSEGAHFI 226

  Fly   239 ADPKVCGTYYVCTNGKNVATYCPTGDYYDDSLGYC 273
            |..|....||.|.||:.|...|..|..:|.....|
  Fly   227 AHQKRQDAYYYCLNGRGVTLDCTPGLVFDAKREEC 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7298	NP_649187.3	ChtBD2	<239..274	CDD:214696	12/35 (34%)
CG7298	NP_649187.3	ChtBD2	286..334	CDD:214696
CG10725	NP_648647.1	CBM_14	35..73	CDD:279884	8/37 (22%)
		CBM_14	83..134	CDD:279884	10/59 (17%)
		CBM_14	150..192	CDD:279884	11/47 (23%)
		ChtBD2	216..264	CDD:214696	15/46 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444210
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950