DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7298 and CG7248

DIOPT Version :9

Sequence 1:	NP_649187.3	Gene:	CG7298 / 40210	FlyBaseID:	FBgn0036948	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_648530.1	Gene:	CG7248 / 39356	FlyBaseID:	FBgn0036229	Length:	796	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	94/428 - (21%)
Similarity:	145/428 - (33%)	Gaps:	112/428 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CLMGGQ-------ALGDAILEGNYNVTAVCTAVKVGTQLGSIESCQTYYVCQSTGPVQSSCQSGY 69
            |::..|       :|.:...|..||                   |..|..|..:......|..|.
  Fly    51 CVVSSQQNSTYCESLSNGFYEYPYN-------------------CSAYITCYDSCADLEYCPDGK 96

  Fly    70 SYDYKRSSCYPSSEVDC-----------YWGVENPCAG-KNNTWVPNTAVCGGWFYCLEGKSAGS 122
            .::.....|.....|||           ....||||.| :|||.:|:...|..::.|:..:|. .
  Fly    97 LFNSPLQICDTPGAVDCEPLPYPTPSPTESPPENPCLGTRNNTLLPSAENCNEFYLCVNDQSK-V 160

  Fly   123 GNCPVNQKFDTTTLAC-------VYG--TCSNTQGTNETVLESL--CDVVPPGQYFGDTESCSTW 176
            ..||....|:.....|       .||  |..:...|.....||.  |:....|.:|.|.|:|..:
  Fly   161 YRCPGEMLFNPDLNICDDKDNVWCYGDRTTPDPLDTTTPAEESFTKCEDQEKGTFFPDPENCQQY 225

  Fly   177 HYCESTSTGLVLQSGKCSANNQTAYNVLANQCTYESASVCSRVTNIPLSDAAVSCSTN------- 234
            :||....:..:|   .|..:|.  :|.::..|..:.|....|.|. |.|...:..|::
  Fly   226 YYCWGNKSYTIL---PCPVDNW--FNPISGNCGPDIAPDACRETT-PTSTPTIDTSSSTTVAPTS 284

  Fly   235 -----GAKSADPKV---------CGTYYVC-TNGKNVATYCPTGDYYDDSLGYCVSRQVATPVAG 284
                 |...||.::         |.:|.:| .||::....||:..::|...|.|...  .:|.|
  Fly   285 TEDSVGNPCADQELGASFPIKSDCQSYLLCLNNGESTTAKCPSNAWFDPKTGDCGPN--VSPTA- 346

  Fly   285 CNRCQYATSTFVNAVDS-------------------NNCSTYYYCNSQGEATLNTCPADTFFDES 330
               |..:..|...||.:                   .||..|..|...||:|:..|..:::||..
  Fly   347 ---CLESFETTTTAVTTQAPKDPCADQELGTSYPLVTNCQQYILCMGNGESTVANCIYNSWFDPQ 408

  Fly   331 RQGCKSDDDLSTYVPLNGACK--GATAEGSEETDNSTT 366
            ...|..|...:       |||  |.|......|..:|:
  Fly   409 TGNCGPDVSPT-------ACKESGVTTASPTTTSQATS 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7298	NP_649187.3	ChtBD2	<239..274	CDD:214696	11/44 (25%)
CG7298	NP_649187.3	ChtBD2	286..334	CDD:214696	14/66 (21%)
CG7248	NP_648530.1	CBM_14	62..113	CDD:279884	11/69 (16%)
		CBM_14	136..182	CDD:279884	11/46 (24%)
		CBM_14	207..261	CDD:279884	14/58 (24%)
		CBM_14	293..347	CDD:279884	14/59 (24%)
		CBM_14	367..421	CDD:279884	12/60 (20%)
		CBM_14	470..522	CDD:279884
		CBM_14	544..597	CDD:279884
		CBM_14	630..678	CDD:279884
		CBM_14	710..758	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950