Protein Alignment CG7335 and KHK

DIOPT Version :10

• Sequence 1: NP_649180.1
• Gene: CG7335 / 40203
• FlyBaseID: FBgn0036941
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_006712071.1
• Gene: KHK / 3795
• HGNCID: 6315
• Length: 371
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 60/253 - (23%)
• Similarity: 99/253 - (39%)
• Gaps: 83/253 - (32%)

  Fly    30 KRHVLAVGSCTLDMITIVD-LPLFPGQVQRTTEGSWRRGGPAANICTVWRRLGLECEFLGVLS-- 91
            ::.:|.||...||:|::|| .|....:: |.....|:|||.|:|.|||...||..|.|:|.::
Human     3 EKQILCVGLVVLDVISLVDKYPKEDSEI-RCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPG 66

  Fly    92 ------------------RVRAFES--------------------------LLNGFQSQGIDISH 112
                              |...|::                          |:..|:.:|:|:|.
Human    67 HVADSFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDSFLVADFRRRGVDVSQ 131

  Fly   113 ------------CPLTNHRPAHRSIIVQRNVDTRTMLEFANANQELTYQQFVGAVDYQK-----Y 160
                        |.:.|:...:|:|::.   ||..              ..|.|.|::|     :
Human   132 VAWQSKGDTPSSCCIINNSNGNRTIVLH---DTSL--------------PDVSATDFEKVDLTQF 179

  Fly   161 SWIHFECRNPVEMLRMVLAVIQFNER-CPESRITLSVDLDNLRPATMLMASMVDYVFA 217
            .|||.|.||..|.::|:..:...|.| .||.:|.:||:::..|.....:....|.|.|
Human   180 KWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVGA 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7335	NP_649180.1	Ketohexokinase	32..357	CDD:238914	60/251 (24%)
KHK	XP_006712071.1	ribokinase_pfkB_like	5..>235	CDD:469648	58/247 (23%)