Protein Alignment gig and rad

DIOPT Version :9

• Sequence 1: NP_524177.1
• Gene: gig / 40201
• FlyBaseID: FBgn0005198
• Length: 1847
• Species: Drosophila melanogaster
• Sequence 2: NP_001285176.1
• Gene: rad / 32253
• FlyBaseID: FBgn0265597
• Length: 1799
• Species: Drosophila melanogaster
• Alignment Length: 1177
• Identity: 229/1177 - (19%)
• Similarity: 356/1177 - (30%)
• Gaps: 431/1177 - (36%)

  Fly   967 RHTYS---PCPS-----MPKRLPAAEF-----LLKDGVSQTWLVGNNLVTITTSGCPSAPAR--- 1015
            ||..|   ||.|     ..|.:.|..|     ::...|...|..||....:.......:..|
  Fly     5 RHYRSMDQPCSSTCVVIRKKTMTAICFVCNLPIMSHQVGLVWQGGNGWDDLVREQLEESTIRQRL 69

  Fly  1016 SGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRY---------------TKVSLQHSSGNE 1065
            .|..:..||:...||.|          ||...:|.||.               ||...||.|..:
  Fly    70 GGRRDSAAQITTPPSTS----------PPPGLQRRRRSSLAQLTDILREWSGGTKQQQQHHSQQQ 124

  Fly  1066 -------SAGSTEL----------------TSSSSSNSAAAGGH----------PHRQISNSSTA 1097
                   |....:|                ||:::..|..|||.          |.::..:|:.:
  Fly   125 QQQLQQASRSKAQLNRRETLADLARSLPWRTSTTTDASTGAGGSGGGGCTTYMAPRKRRESSADS 189

  Fly  1098 SLDAL-SRRGSNPEAL--------GSALGE---------------GAHTGSNTSLLGNSLSQSSV 1138
            .:.:: |||.||....        ..|:.|               .:..||..|.|.:|...|:|
  Fly   190 GIRSMRSRRDSNTAEFVRHWNRRESGAVEEQPSVSVPVVVECSKSASRRGSGESYLSSSRRDSNV 254

  Fly  1139 SMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSW--------------ITRIQNPITN---DC 1186
                 :|.|...|                |.|....              ..:.|.|.|:   .|
  Fly   255 -----AGRVTTPP----------------PPGKYQMTKKRDSLAAPEFPNFRQEQRPSTSSAGSC 298

  Fly  1187 FGQELPFNNVVSLFLPTAHGGVFGPDNTIQA-PPHTLADPEPEPEAEVNAATAPQASALRSRMVA 1250
            ....:|..:..|.....||..|   |:..|| ||.|:......|.|  .:.|||:.
  Fly   299 SDHSMPLISTHSSTHHLAHQQV---DSACQALPPPTIITSSVTPPA--TSPTAPKG--------- 349

  Fly  1251 KARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTG--------GAAAIPIPRVPASGKRGKEAALC 1307
             .|..|.|        .|..|...:.:|.:|...        .|.|.....:|...:||.:.||
  Fly   350 -RRDSQTQ--------CGRVNRRDSKAGVSPERAPRLQRLQRQATAFDEGCLPGGSRRGSQPAL- 404

  Fly  1308 GSVSDGEADD--------DSLAFEDAQSRARNPVRRVNSSPEMS----SSWRQSFL--------- 1351
               |....||        |||: .|:.||......|.:.||:.|    .|.|:..|
  Fly   405 ---SPDPPDDCERRTSRRDSLS-PDSASRGGRRDSRTHLSPDRSHERDGSPRRHTLRRQSSSAAR 465

  Fly  1352 ------------TNKPTPLSQEPVKTTADEPQSLLTLKKKTVQ----------YSTKDMRVSCEA 1394
                        :..|:|.|:...:||.::.|.....::.|.:          .||.:..:.|..
  Fly   466 SPRSPDSNSCCSSRDPSPCSRPQTQTTVEQNQRPAIRRQSTTEEILIARGFRRQSTTEEMIRCRN 530

  Fly  1395 IPEEIAGSTP--------PSQAAAL------------------ALQPESGTLPPKQHSADDVSSH 1433
            ...:.:.|..        .|.|..:                  :.|.|...|....|..::....
  Fly   531 FRRQSSQSDDVCRYRGRRDSSAQIIDGTIGTMTVETTSTFFDSSTQTEPSPLYDNNHYHEECLRC 595

  Fly  1434 VAGGSNLQAGG-----------------------------STLKLGKP----------------- 1452
            .:.|.||....                             ..|:..||
  Fly   596 NSCGLNLTGPNQKRARRFKNQILCDLHFADVALMECSDFMQQLRSFKPQSLGCAVARRKSSTTLI 660

  Fly  1453 -PLSP-------------GQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVIT----- 1498
             ||.|             ...|..|.....|....::|.|..:...|.|.......|..:
  Fly   661 FPLPPQACSDEFCEEYPHNLMPTPGYWIECSRQKITMPTPHTIWDESDSEHEDIRAGSASDAYLE 725

  Fly  1499 ---SDYDNGNNGNGDMMRGRSKT------------------------------------------ 1518
               ||....:..:......|.||
  Fly   726 RECSDLYEDDEDSEATPSPRKKTTIEEQWDQQGAFELISVEQETYEKYFYGTEHWNYFTSDEDLG 790

  Fly  1519 ---ISVVREVNNGNTR---PPPASSFRNFGAAKPPINTKLCMNPSFIFMQLY-------TTGQLG 1570
               :|:.:|..||..:   ...|.|:...|          .:..|.:|...|       :.|:..
  Fly   791 PVILSIKQETLNGRDQFRILVRAGSYTVHG----------LIPASCVFADRYNREEVVRSLGKEV 845

  Fly  1571 VTDEPLKVG--PENSSAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNI 1633
            ..:.||.:|  |:....:..:|.|......|:||::|.:.|...| :||.|:..|..:.|||..:
  Fly   846 NLNPPLTLGQLPDTPEELLKLDQVFIKSELKVGVIFVKEDQYTEE-QILDNNENSPLFDEFLTLL 909

  Fly  1634 GTLVSLKEAEQNNLFIMLDRNGAD------GKFAYI--WKDDILQVTFHVATLMPTNLQDDPNCN 1690
            |..|.|:..::.       :.|.|      |.|:..  |::  :::.|||:||:|.. :.||...
  Fly   910 GDRVRLRGFDKY-------KGGLDTVHDLTGLFSVYTNWRN--IEIMFHVSTLLPYE-KHDPQKL 964

  Fly  1691 EKKSHIGNDFVKIIYNESGEEYNLNTISGQFNYACVIVEPLDLNSNRVYVKARSEISKFVCHAEY 1755
            ::|.|||||.|.:::.|:.     ||   :|:.||:       .|:.::......:|..:.|...
  Fly   965 QRKRHIGNDIVCVVFLEAD-----NT---RFSPACI-------KSHFLHTFILVRVSARIKHKPT 1014

  Fly  1756 RIVSDRSAPLLARQMALHANLASLVYQSVQKKHPYASNWL-------ER--------LRKLKRLR 1805
            |.    ...::.|. .:.|....|..|||.:|.|....||       ||        .|..:|.|
  Fly  1015 RY----EVSVVTRD-EVGAYKPYLWEQSVFEKGPMFREWLLTKIVNGERASYSAPKFARMQERTR 1074

  Fly  1806 SKLIEGL 1812
            |:::|.|
  Fly  1075 SQMLEDL 1081

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gig	NP_524177.1	DUF3384	40..467	CDD:288697
		HEAT repeat	484..515	CDD:293787
		Tuberin	566..882	CDD:281532
		Rap_GAP	1617..1802	CDD:280332	52/207 (25%)
rad	NP_001285176.1	LIM	<583..623	CDD:259829	4/39 (10%)
		Rap_GAP	893..1074	CDD:280332	53/210 (25%)
		BTB	<1464..1523	CDD:295341
		BTB	<1467..1526	CDD:197585
		BACK	1544..1646	CDD:197943

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910