DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7365 and plb1

DIOPT Version :9

Sequence 1:	NP_001262088.1	Gene:	CG7365 / 40200	FlyBaseID:	FBgn0036939	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_017207306.2	Gene:	plb1 / 560649	ZFINID:	ZDB-GENE-120709-93	Length:	1078	Species:	Danio rerio

Alignment Length:	374	Identity:	139/374 - (37%)
Similarity:	191/374 - (51%)	Gaps:	55/374 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PRTRALLEFCDADHGPGKRSPERPTSVHRLRPGDIDVIGAMGDSLTAGNGIFATNLLHVTVENRG 134
            |.|....:|...|..|   |...|||||.||||||.|:.|:|||||||.|..|.|:|.:..|.||
Zfish   664 PPTNWGSDFSCVDTAP---SNTLPTSVHSLRPGDIKVVAALGDSLTAGFGAKAKNILQLPDEERG 725

  Fly   135 VVWSIGGQYDWRKYLTLPNILKEFNPNLYGYAIKDGISTDRSSR---FDVAELAAMSRDMPHMAK 196
            |.|||||........|||||.|:|||:::|:      |..:|.|   |::|...|.::::|..|:
Zfish   726 VSWSIGGDDTLETVTTLPNIFKKFNPSVFGF------SKGKSKRPNGFNMAVGGAKAQNIPAQAR 784

  Fly   197 VLVRRMQRDPRVNMTSDWKLVTLFIGNNDFCTDICYYPEPEKTVDWHERNMLKTYRY---LRDN- 257
            .|:..::....|:...||||||||||.||.| ..|           |:|..|.:.:|   :||:
Zfish   785 DLITALKESKDVDFEKDWKLVTLFIGGNDLC-QYC-----------HDRAALSSSKYIGHIRDSL 837

  Fly   258 ------VPRLMLNIV---PAPNLRFLTNLT-GLPPICYSTLRFECPCLMGKGKGQLDYLEGIMKR 312
                  |||:::|:|   ...:||.:...| |    |....:..|||.:...:......|  ||:
Zfish   838 DMLYNEVPRVLVNLVEILQIEDLRMIKRDTLG----CSLLQKNMCPCFLSPRENSPQMNE--MKK 896

  Fly   313 WIAKDFEIANREEF-------NTETFTINVQPFSQFQDFPRTRSGQTDTRFFSEDCFHLSQRGHA 370
             :.:|.: |..|..       ....|.:.:|||.:....|..:.|:.|..|||.||||.|:||||
Zfish   897 -VNRDLQ-AEAERLVYGGRYDGRHDFAVVLQPFFENTVVPMDKDGKPDVSFFSVDCFHFSERGHA 959

  Fly   371 AAANSIWNNMLELPGHKSGFATHLFE--TFRCPSEMRPFLITRENSRPE 417
            ..|.:|||||||..|.|..:....::  ..|||:|..||:.||.||.||
Zfish   960 EMAIAIWNNMLEPVGSKQNYNNFTYDRSKIRCPTEEHPFIFTRINSGPE 1008

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7365	NP_001262088.1	Phospholipase_B_like	95..385	CDD:238862	117/313 (37%)
plb1	XP_017207306.2	SGNH_hydrolase	47..260	CDD:321319
		Phospholipase_B_like	326..621	CDD:238862
		Phospholipase_B_like	686..974	CDD:238862	117/313 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583903
Domainoid	1	1.000	157	1.000	Domainoid score	I4114
eggNOG	1	0.900	-	-		E1_KOG3670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1232962at2759
OrthoFinder	1	1.000	-	-		FOG0001722
OrthoInspector	1	1.000	-	-		mtm6595
orthoMCL	1	0.900	-	-		OOG6_104972
Panther	1	1.100	-	-	LDO	PTHR21325
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.710