DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7365 and plb1

DIOPT Version :9

Sequence 1:	NP_001262088.1	Gene:	CG7365 / 40200	FlyBaseID:	FBgn0036939	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_031758328.1	Gene:	plb1 / 100495859	XenbaseID:	XB-GENE-997742	Length:	1423	Species:	Xenopus tropicalis

Alignment Length:	360	Identity:	129/360 - (35%)
Similarity:	194/360 - (53%)	Gaps:	38/360 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 CDADHGPGKRSPERPTSVHRLRPGDIDVIGAMGDSLTAGNGIFATNLLHVTVENRGVVWSIGGQY 143
            |.|. ||   |.:.|||||:|||.||.|:.|:||||||..|..:|::..:..|.|||.|||||..
Frog  1039 CQAT-GP---SSQVPTSVHKLRPADIKVVAALGDSLTAAFGAKSTSMAELGTEYRGVSWSIGGDG 1099

  Fly   144 DWRKYLTLPNILKEFNPNLYGYAIKDGISTDR-SSRFDVAELAAMSRDMPHMAKVLVRRMQRDPR 207
            ...:..|||||||:||||:.|::    ...|| ::.|:||...|.:.||...|..||.:|:....
Frog  1100 TLEECTTLPNILKKFNPNIKGFS----TGVDRENAMFNVAVGGAKAEDMTSQATNLVNKMKESTV 1160

  Fly   208 VNMTSDWKLVTLFIGNNDFCTDICYYPEPEKTVDWHERNMLKTYRYLRDNVPRLMLNIVPAPNLR 272
            :|...|||::|:|||.||.| ..|:..: ..:|..|..::......|...:||:.:|:|.
Frog  1161 INFNEDWKVITIFIGGNDLC-QFCHNRD-RYSVHNHVTHVKNALDILYKEIPRVFVNLVE----- 1218

  Fly   273 FLTNLTGLPPICYSTLRFE------CPCLMGKGKGQLDYLEGIMKRWIAKDFE-----IANREEF 326
             :..:.||..:..:|....      |||.:...:|..:..|  |||: .||.:     :|::.:
Frog  1219 -ILEVEGLRRVKANTFGCTLLKPNLCPCFINPREGSPELYE--MKRF-NKDLQSQVTALADKYQ- 1278

  Fly   327 NTETFTINVQPFSQFQDFPRTRSGQTDTRFFSEDCFHLSQRGHAAAANSIWNNMLELPGHKSGF- 390
            :.|.||:.||||.:....|..::|..|..|||.||||.::||.:..|.::||:|||..|.|..:
Frog  1279 DREDFTVVVQPFFKNSVLPVDKNGDVDISFFSVDCFHFTERGQSEMAKALWNSMLEPIGQKQEYN 1343

  Fly   391 -ATHLFETFRCPSEMRPFLITRENS----RPEFVI 420
             .|:.....:||::.:|:|.|.:||    .||.|:
Frog  1344 NFTNDRSNLKCPTQDKPYLFTLKNSGLPEPPETVV 1378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7365	NP_001262088.1	Phospholipase_B_like	95..385	CDD:238862	109/301 (36%)
plb1	XP_031758328.1	SGNH_hydrolase	58..258	CDD:412717
		Phospholipase_B_like	335..630	CDD:238862
		Phospholipase_B_like	691..986	CDD:238862
		Phospholipase_B_like	1051..1337	CDD:238862	109/301 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4094
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1232962at2759
OrthoFinder	1	1.000	-	-		FOG0001722
OrthoInspector	1	1.000	-	-		otm47574
Panther	1	1.100	-	-	LDO	PTHR21325
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.110