DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir76b and GLR2.3

DIOPT Version :9

Sequence 1:	NP_649176.1	Gene:	Ir76b / 40198	FlyBaseID:	FBgn0036937	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_001325281.1	Gene:	GLR2.3 / 817007	AraportID:	AT2G24710	Length:	919	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	110/546 - (20%)
Similarity:	187/546 - (34%)	Gaps:	165/546 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NLIQMGE---------NGTLSPVTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIG- 81
            |:|..||         ||.:..:                |....::..::..|..|:.:: |.|
plant   414 NIINTGEKSIGFWKEGNGLVKKL----------------DQQASSISALSTWKDHLKHIV-WPGE 461

  Fly    82 -------------GKHLRIATLEDFPLSYTEVLE-------NGT---------------RVGHGV 111
                         ||.|||...:  ...||::::       |.|               .:.:.|
plant   462 ADSVPKGWQIPTKGKKLRIGVPK--RTGYTDLVKVTRDPITNSTVVTGFCIDFFEAVIRELPYDV 524

  Fly   112 SFQIIDFLKK------KFN-FTYEVVVPQ-DNIIGSPSDFDRSLIEMVN-SSTVDLAAAFIPS-- 165
            |::.|.|.|.      .:| ..|:|.:.: |.::|     |.::  :|| ||.||....||.|
plant   525 SYEFIPFEKPDGKTAGNYNDLVYQVYLGRYDAVVG-----DTTI--LVNRSSYVDFTFPFIKSGV 582

  Fly   166 -----LSD--QRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPI 223
                 ::|  :|.::.:                          :.|..:.:|:...:|...||..
plant   583 GLIVEMTDPVKRDYILF--------------------------MKPLSWKLWLTSFISFFLVGCT 621

  Fly   224 IYALIILRNRLTGDGQQTP-YSLGHCAWFVYGALMKQGSTLSP----IADSTRLLFATWWIFITI 283
            ::.|...||   .|....| :......||.:..::     .:|    .:...|.|...|:..:.:
plant   622 VWVLEYKRN---PDFSGPPRFQASTICWFAFSTMV-----FAPRERVFSFWARALVIAWYFLVLV 678

  Fly   284 LTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNY 348
            ||..|||:|.:.||..|......:::.:|.|        |..|.|. ||:.....:..|....:.
plant   679 LTQSYTASLASLLTSQKLNPTITSMSSLLEK--------GETVGYQ-RTSFILGKLKERGFPQSS 734

  Fly   349 AVFSDETNDTYNLQNYVEKNGYV---FVRDRPAINIMLYRDYLYRKTVSFSDEKVHC-PFAMAKE 409
            .|..|...:...|.:...|.|.|   |: :.|.:.:.|.:               .| .:.|.:|
plant   735 LVPFDTAEECDELLSKGPKKGGVSGAFL-EIPYLRLFLGQ---------------FCNTYKMVEE 783

  Fly   410 PFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAE-ICPQDLGG-------TER 466
            ||......|.:||||.|.......:|.:.||.....|.:......| .||..:..       |.|
plant   784 PFNVDGFGFVFPIGSPLVADVSRAILKVAESPKAMELERAWFKKKEQSCPDPITNPDPNPSFTSR 848

  Fly   467 QLRNGDLMMTYYIMLAGFATALAVFS 492
            ||.....:..:..:|.....||..|:
plant   849 QLDIDSFLFLFVGVLLVCVMALGNFT 874

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	84/402 (21%)
GLR2.3	NP_001325281.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910