DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir76b and grik1a

DIOPT Version :10

Sequence 1:NP_649176.1 Gene:Ir76b / 40198 FlyBaseID:FBgn0036937 Length:636 Species:Drosophila melanogaster
Sequence 2:XP_009303592.2 Gene:grik1a / 798001 ZFINID:ZDB-GENE-030131-6502 Length:919 Species:Danio rerio


Alignment Length:523 Identity:114/523 - (21%)
Similarity:199/523 - (38%) Gaps:106/523 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 NLIQMGENGTLSPVTE---------LPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIGG 82
            :||.:.|:||...|.:         ..:.|..|..|.:       |..|...|    .:.|.:..
Zfish   393 DLISLKEDGTAKRVADGASRPNKLWTKIGVWNSYTGLN-------LTEIKDNK----NITDSLAN 446

  Fly    83 KHLRIATLEDFP-LSY---TEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSD- 142
            :.|.:.|:.:.| :.|   .:||....|. .|....::..|.....|||||.:..|...|:.:| 
Zfish   447 RTLIVTTILENPYVMYKKSDKVLYGNDRF-EGYCLDLLKELSNILGFTYEVKLVTDGKYGAQNDK 510

  Fly   143 -----FDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVM------QRPRESA 196
                 ..|.||:.:    .|||.|.:       :..|.....:|..:..|.:      ::|..:.
Zfish   511 GEWNGMVRELIDHI----ADLAVAPL-------TITYVREKVIDFSKPFMTLGISILYRKPNGTN 564

  Fly   197 SG-SGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTPY----------------- 243
            .| ...|.|....:|:.:|::.|.|..:::.:          .:.|||                 
Zfish   565 PGVFSFLNPLTPDIWMYVLLACLGVSCVLFVI----------ARFTPYEWYNPHPCNPSSEVVEN 619

  Fly   244 --SLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYN 306
              :|.:..||...|||:|||.|.|.|.|||:|...||.|..|:.|.|||||.||||:.:...|.:
Zfish   620 NFTLLNSLWFGVAALMRQGSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPID 684

  Fly   307 TVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYA---VFSDETNDTYNLQNYVEKN 368
            :.:|:..:.:         :||.......:::...:...:.|.   .|.....:|..::|  .|:
Zfish   685 SADDLAKQTR---------IEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKN--SKD 738

  Fly   369 GYVFVRDRPAINIMLYRDY---LYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLF 430
            |         |..:|..||   :...::.:..:: :|...........|......||||......
Zfish   739 G---------ITRVLTTDYALLMESTSIEYITQR-NCNLTQVGGLIDSKGYGVGTPIGSPYRDKV 793

  Fly   431 DPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTEL 495
            ...:|.|.|.|.: |:.|........||::.......|...::...:.::.||...::.|...|.
Zfish   794 TIAILQLQEEGKL-HMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEF 857

  Fly   496 MFR 498
            :::
Zfish   858 IYK 860

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir76bNP_649176.1 Lig_chan-Glu_bd 83..192 CDD:463166 27/124 (22%)
Lig_chan 209..458 CDD:459656 63/273 (23%)
grik1aXP_009303592.2 None

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