Protein Alignment Ir76b and Grid1

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_077354.1
• Gene: Grid1 / 79219
• RGDID: 68366
• Length: 1009
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 153/614 - (24%)
• Similarity: 244/614 - (39%)
• Gaps: 107/614 - (17%)

  Fly    74 REMLDWIGGKHLRIATL--EDFPLSYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNI 136
            |.|...:.|..|::.|:  |.|.:....:|....|. .|.|..::|.|.|...|.||:....|..
  Rat   428 RPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRY-KGFSIDVLDALAKALGFKYEIYQAPDGR 491

  Fly   137 IGSP---SDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG 198
            .|..   :.::..:.|:: |...|||.:.|....::.|.|.:|...:|....|:: ::|.|..|.
  Rat   492 YGHQLHNTSWNGMIGELI-SKRADLAISAITITPERESVVDFSKRYMDYSVGILI-KKPEEKISI 554

  Fly   199 SGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQT--------PYSLGHCAWFVYGA 255
            ..|.|||:|.||..|..::..||.:|:.|    ||:.....|:        ..:|....|.||||
  Rat   555 FSLFAPFDFAVWACIAAAIPVVGVLIFVL----NRIQAVRSQSATQPRPSASATLHSAIWIVYGA 615

  Fly   256 LMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTK-NKHFV 319
            .::||...|..:.:.|::..:||:|..|:.|.|||||.||||:|:...|..|..|:..: ...:.
  Rat   616 FVQQGGESSVNSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDSPVRTFQDLSKQLEMSYG 680

  Fly   320 SMRGGGV-EY-AIRTTN-----ESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRP 377
            ::|...| || ..:.||     .:.:.|.|.|..|....:..:|.:..::. .:|..|.|:.|
  Rat   681 TVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADNCVSNPSEGIRK-AKKGNYAFLWD-- 742

  Fly   378 AINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGI 442
             :.::.|        .:.:|:  .|...:.......|....|...||....||...:|.|.::|.
  Rat   743 -VAVVEY--------AALTDD--DCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGD 796

  Fly   443 VKHLSKRNLPSAEICPQDLGGTERQLRNGDLMM------TYYIMLAGFATALAVFSTELMFRYVN 501
            :..|.::..|....|  ||........:|..:.      .:.|:..|...|..|.:.||.:....
  Rat   797 LDVLKQKWWPHTGRC--DLTSHSSAQTDGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNR 859

  Fly   502 SRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLNS------GHGQL-----------LGASTHG 549
            ..||..|     ..:..|.:.|        .||:||      .|.|:           :|.....
  Rat   860 CHQETPK-----EDKEVNLEQV--------HRRINSLMDEDIAHKQISPASIELSALEMGGLAPS 911

  Fly   550 QNVTPPPPYQ------SIF--NGGSHGDPLNRWRRPLANGNALGNGVLLGGDSEGGVRRLINGRD 606
            |.:.|...||      |.|  ...|||.     .|.|::|.:....:.|   |.......|..:
  Rat   912 QALEPTREYQNTQLSVSTFLPEQSSHGT-----SRTLSSGPSSNLPLPL---SSSATMPSIQCK- 967

  Fly   607 YMVFRNPNG----QSQLVPVRSPSAALFQ 631
               .|:|||    ||   ||::|....||
  Rat   968 ---HRSPNGGLFRQS---PVKTPIPMSFQ 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	98/374 (26%)
Grid1	NP_077354.1	Interaction with CBLN1. /evidence=ECO:0000250|UniProtKB:Q61627	21..436		2/7 (29%)
		PBP1_iGluR_delta_1	25..423	CDD:107387
		ANF_receptor	41..400	CDD:279440
		PBP2_iGluR_delta_1	436..806	CDD:270448	102/390 (26%)
		Lig_chan	564..841	CDD:278489	72/296 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..960		8/36 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910