Protein Alignment Ir76b and grin1a

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_073791110.1
• Gene: grin1a / 767745
• ZFINID: ZDB-GENE-051202-1
• Length: 966
• Species: Danio rerio
• Alignment Length: 625
• Identity: 117/625 - (18%)
• Similarity: 212/625 - (33%)
• Gaps: 175/625 - (28%)

  Fly    55 DADAPVETLETINRKKPKL---------------REMLDWIGGK-----------HLRIATLEDF 93
            |.|........:|.:|.:|               :..:.|.||:           .|:|.|:...
Zfish   360 DGDRKYAHYSILNYQKSRLIQVGIYNGTQVVMNKQRKIIWPGGETERPRGFQMSTRLKIVTIHQE 424

  Fly    94 PLSYT-----------EVLENGTRVG---------------------HGVSFQIIDFLKKKFNFT 126
            |..|.           |...||..:.                     :|....::..|....|||
Zfish   425 PFVYVKPTTLEGTCKEEYTPNGVLIKKVICTGPNETIPGRPIVPQCCYGFCIDLLIKLALTMNFT 489

  Fly   127 YEVVVPQDNIIGSPSDFDRSLIEMVNSST---------------VDLAAAFIPSLSDQRSFVYYS 176
            |||.:..|...|:.        |.||:|.               .|:..|.:...:::..::.:|
Zfish   490 YEVHLVADGKFGTQ--------ERVNNSNKKEWNGMMGELLGGLADMIVAPLTINNERAQYIEFS 546

  Fly   177 TTTLDEGEWIMVMQR-PRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLTGDG-- 238
            .....:|..|:|.:. ||.:.  ...:.||:..:|:|:.:|:..|..::|.|    :|.:..|
Zfish   547 KPFKYQGLTILVKKEIPRSTL--DSFMQPFQSTLWLLVGLSVHVVAVMLYLL----DRFSPFGRF 605

  Fly   239 -------QQTPYSLGHCAWFVYGALMKQG-STLSPIADSTRLLFATWWIFITILTSFYTANLTAF 295
                   ::...:|....||.:|.|:..| ...:|.:.|.|:|...|..|..|:.:.|||||.||
Zfish   606 KVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAF 670

  Fly   296 LTLSKFTLPYNTVNDILTKNKH----FVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETN 356
            |.|.:.......:||...:|..    :.:::...|:...|...|..:|...|.::||...::.
Zfish   671 LVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEA-- 733

  Fly   357 DTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYP 421
                :|...:...:.|:.|...:..               :....|......|.|.:.    .:.
Zfish   734 ----IQAVRDNKLHAFIWDSAVLEF---------------EASQKCDLVTTGELFFRS----GFG 775

  Fly   422 IG----SNLSQLFDPELLHLVESGIVKHL-----------SKRNLPSAEICPQDLGGTERQLRNG 471
            ||    |...|.....:|...|:|.::.|           |:.|.| |.:..:::.|
Zfish   776 IGMRKDSPWKQNVSLAILSSHENGFMEDLDKTWVRYQECDSRSNAP-ATLTFENMAG-------- 831

  Fly   472 DLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLN 536
                .:.::..|.|..:.:...|:.::            ||...|....|....:  :..||:..
Zfish   832 ----VFMLVAGGIAAGIFLIFIEIAYK------------RHKDARRKQMQLAFAA--VNVWRKNL 878

  Fly   537 SGHGQLLGASTHGQNVTPPPPYQSI------FNGGSHGDP 570
            ..:.:..|:...|...||..|..|:      .:|.:..||
Zfish   879 QDNKESSGSQAVGAAGTPSLPSSSVETQDDRKSGRADSDP 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	28/167 (17%)
		Lig_chan	209..458	CDD:459656	58/277 (21%)
grin1a	XP_073791110.1	None