Protein Alignment Ir76b and grin2ab

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_009304490.1
• Gene: grin2ab / 570493
• ZFINID: ZDB-GENE-070424-223
• Length: 1445
• Species: Danio rerio
• Alignment Length: 669
• Identity: 146/669 - (21%)
• Similarity: 237/669 - (35%)
• Gaps: 172/669 - (25%)

  Fly    84 HLRIATLEDFPLSYTEVLE--NGTRVGHGVSFQ--------------------IIDFLKK---KF 123
            ||.|.|||:.|....:.::  .||.:.:.|..:                    .||.|||   ..
Zfish   395 HLSIVTLEERPFVIVDDVDILTGTCMRNSVPCRKHIKDNTTEGSYVKKCCKGFCIDILKKIARNV 459

  Fly   124 NFTYEVVVPQDNIIGSPSD--FDRSLIEMVNSSTVDLAAAFIPSLSDQRS-FVYYSTTTLDEGEW 185
            .|||::.:..:...|...:  ::..:.|:|....|....:.  :::::|| .:.:|...::.|..
Zfish   460 KFTYDLYLVTNGKHGKKINNVWNGMVGEVVYKKAVMAVGSL--TINEERSEAIDFSVPFVETGIS 522

  Fly   186 IMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPI-------IYALIILRNRLTGDGQQTP- 242
            :|| .|...:.|.|..|.||...||:::.|.||.|..|       |..|...||...|.....|
Zfish   523 VMV-SRSNGTVSPSAFLEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQGKDPHGPS 586

  Fly   243 YSLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWIFITILTSFYTANLTAF----------- 295
            :::|...|.::|.:......: :|...:::.:.:.|..|..|..:.|||||.||
Zfish   587 FTIGKAVWLLWGLVFNNSVPVQNPRGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVT 651

  Fly   296 -LTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTY 359
             |:..||..||:     .:....|.::..|..|..||.        |....:.|.|...:|....
Zfish   652 GLSDRKFQSPYS-----YSPPFRFGTVPNGSTERNIRK--------NYPAMHQYMVKYHQTGVVD 703

  Fly   360 NLQNYVEKNGYV--FVRDRPAINIMLYRD-----------YLYRKTVSFSDEKVHCPFAMAKEPF 411
            .|.:.  |.|.:  |:.|...:|.|..||           |:: .|..:.       .||.|
Zfish   704 ALVSL--KTGKLDAFIYDAAVLNYMAGRDDGCKLVTIGSGYIF-ATTGYG-------IAMQK--- 755

  Fly   412 LKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGT-ERQLRNGDLMM 475
                       ||...:|.|..:|.::..|.::.|..:.|..  ||..:.... ..||...::..
Zfish   756 -----------GSYWKRLVDLAILGIIGDGEMEELEAQWLTG--ICHNEKNEVMSSQLDVDNMAG 807

  Fly   476 TYYIMLAGFATALAVFSTELMF----RYVNSRQEANK-----------WA-RHGI---------- 514
            .:|::.|..|.:|..|..|.:|    ||..:...:.:           |: .||:
Zfish   808 VFYMLAAAMALSLITFVWEHLFYWRLRYCFTGLCSGRPGILFTISRGIWSCIHGVHIELKKAPEL 872

  Fly   515 GRTPNGQSV---------------APSRWLRGWRRLNSGHGQLLGASTHGQNVTPP-PPYQSIFN 563
            ..:|....:               :|.|.:.......||..:|:|.. .|.|:.|. |||.:...
Zfish   873 DFSPQANMLHLLKSAKEITTLGVTSPKRPMSSILPPTSGLLELMGGG-KGNNLAPKNPPYSNTST 936

  Fly   564 GGSHGDPLNRWRRPLANGNALGN----------GVLLGGDSEGGVR---------RLINGRDYMV 609
            ..|     ||.:.||.|....|.          ||...|.|.||..         |.:..:....
Zfish   937 MLS-----NRLKEPLNNTLLPGQRALSLTDAQPGVAGNGGSTGGGETMRPPASKPRALWKKSVET 996

  Fly   610 FRNPNGQSQLVPVRSPSAA 628
            .|...|.....|..:|.||
Zfish   997 LRQNQGPEDSSPPSAPQAA 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	94/414 (23%)
grin2ab	XP_009304490.1	PBP1_iGluR_NMDA_NR2	25..382	CDD:107373
		ANF_receptor	48..358	CDD:279440
		PBP2_iGluR_NMDA_Nr2	393..790	CDD:270436	99/436 (23%)
		Lig_chan	544..816	CDD:278489	69/310 (22%)
		NMDAR2_C	827..1445	CDD:287527	39/195 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591352
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840