Protein Alignment Ir76b and grin3ba

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_021323058.1
• Gene: grin3ba / 566411
• ZFINID: ZDB-GENE-070912-354
• Length: 1118
• Species: Danio rerio
• Alignment Length: 630
• Identity: 113/630 - (17%)
• Similarity: 200/630 - (31%)
• Gaps: 190/630 - (30%)

  Fly    80 IGGKHLRIATLEDFPLSYT-EVLENG--------------------------------------T 105
            :.|..||:.||.:.|..:| ||.|.|                                      .
Zfish   453 VAGSRLRVVTLVEHPFVFTREVDEEGQCPAGQLCLDPQTNNSEVLNQLFRELEQTNSSSLPTDMR 517

  Fly   106 RVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRS-LIEMVNSSTVDLAAAFIPSLSDQ 169
            :..:|....:::.|.:..:|.:::.:..|...|:......| |:..:.|...|:|.... |::..
Zfish   518 KCCYGYCIDLLEKLAEDMHFEFDLYIVGDGKYGAWKGGRWSGLVGDLLSGVADMAVTSF-SINSA 581

  Fly   170 RSFV------YYSTTTLDEGEWIMVMQRPRESASGSG-LLAPFEFWVWILILVSLLAVGPIIYAL 227
            ||.|      ::||:       :.::.|.:::|:..| .:.|..:.:|:.|.|:|     .|.||
Zfish   582 RSRVIDFTSPFFSTS-------LGILVRSKDTAAPIGAFMWPLHWSMWVGIFVAL-----HITAL 634

  Fly   228 IILRNRLTGDGQQTPYSLGHCAWFVYGALMKQ------GSTL---SPIADSTRLLFATWWIFITI 283
            .|...........||:.......|.|.:.:..      |.|:   :|...:.|.|...|.||..:
Zfish   635 FITLYEWNSPFGMTPHGRNRIRVFSYSSALNLCYAILFGRTVASKTPKCWTGRFLMNLWAIFCLL 699

  Fly   284 LTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNY 348
            :.|.|||||.|.:...|   .:..|:.|     |.|.:....:.:...|..||
Zfish   700 VLSSYTANLAAVMVGEK---TFEEVSGI-----HDVKLHHPSLGFRFGTVRES------------ 744

  Fly   349 AVFSDETNDTYNLQNYVEKNGYV--------------FVRDRPAINIMLYRDYLYRKTVSFSDEK 399
                  :.:.|..:::.|.:.|:              ...|.|.::..:....|....||...:
Zfish   745 ------SAEDYVKKSFPEMHEYMRRFNKPTTPDGVSTLKTDPPQLDAFIMDKALLDYEVSIDAD- 802

  Fly   400 VHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSK---RNLPSAEICPQDL 461
              |......:||..:......|..|.|::.....:......|.:..|..   :.:|    |.:.:
Zfish   803 --CKLLTVGKPFAIEGYGIGLPQNSPLTRNVSEYVSRYKSDGYMDMLHDKWYKVVP----CGKRV 861

  Fly   462 GGTERQLRNG--DLMMTYYIMLAGFATA-LAVFSTELMFRYV----NSRQEANKWAR-----H-- 512
            ......|:.|  .....:.::..|.|.| |.:......||::    ..:|....|..     |
Zfish   862 FAVTETLQMGIQHFSGLFVLLCVGVAGALLTLLGEHAFFRFILPHLRHQQRFKYWLHTSQKIHRA 926

  Fly   513 ----------------------------GIGRTPNGQSVAPS---------RW----LRGWR--- 533
                                        .:.|.|...|..||         :|    ::..|
Zfish   927 INMGCDDERKSEAESSDRCPTLCLSENCNLHRLPPSSSSPPSTSSTSTTTTKWNNQSVKAGREAK 991

  Fly   534 --------RLNSGHGQLLGASTHG-----QNVTPPPPYQSIFNGG 565
                    .|.:.:...|.|..||     :.:...||.|...|||
Zfish   992 EQNKRVHFNLETLNSYQLQAPPHGAERGRRGLVGSPPTQLCSNGG 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/154 (17%)
		Lig_chan	209..458	CDD:459656	52/274 (19%)
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_type1	36..427	CDD:471960
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	81/436 (19%)
		Lig_chan	618..885	CDD:459656	55/304 (18%)