Protein Alignment Ir76b and KaiR1D

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_061498559.1
• Gene: KaiR1D / 4576020
• VectorBaseID: AGAMI1_006981
• Length: 930
• Species: Anopheles gambiae
• Alignment Length: 587
• Identity: 123/587 - (20%)
• Similarity: 223/587 - (37%)
• Gaps: 106/587 - (18%)

  Fly    27 NLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIGGKHLRIATLE 91
            :::::|..|.....|            :::.:.|....|...::.::.|:|.   .|.|.:.|:.
Mosquito   384 DIVELGPQGLRKSGT------------WNSTSGVNFTRTYGEQQKEIVEILQ---NKTLIVTTIL 433

  Fly    92 DFPL----SYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGS----PSDFDRSLI 148
            ..|.    ...|.| .|.....|.:..:|..:.|...|.|.:.:..|...||    ..::|..:.
Mosquito   434 SAPYCMRKDSAEKL-TGNSQFEGYAIDLIHEISKILGFNYTIRLAPDGRYGSHNKETGEWDGMIK 497

  Fly   149 EMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILI 213
            |:: ....|||.|.:....|:...|.::...::.|..::..:..::..:....|:|....|||.:
Mosquito   498 ELL-EQRADLAIADLTITFDREQVVDFTMPFMNLGISVLYRKPVKQPPNLFSFLSPLSLDVWIYM 561

  Fly   214 LVSLLAVGPIIYALIILRNRLT-------------GDGQQTPYSLGHCAWFVYGALMKQGSTLSP 265
            ..:.|.|..:::.|.    |.|             .:..||.::|.:|.||..|:||:||....|
Mosquito   562 ATAYLGVSVLLFILA----RFTPYEWPTPNPCDPHPEKLQTQFTLMNCMWFAIGSLMQQGCDFLP 622

  Fly   266 IADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK-HFVSMRGGGVEYA 329
            .|.|||::...||.|..|:.|.|||||.||||:.:...|..:..|:..:.| .:.::|||.....
Mosquito   623 KAVSTRMVAGMWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTKIKYGALRGGSTAAF 687

  Fly   330 IRTTNESL--SMLNRMIQNNYAVFSDETNDTYNLQNYVE-KNGYVFVRDRPAINIMLYRDYLYRK 391
            .|.:|.|.  .|.:.|.....:||:  .::...::..|: |..|.|:.:..:|..::.|:....:
Mosquito   688 FRDSNFSTYQRMWSFMESARPSVFT--ASNIEGVERVVKGKGSYAFLMESTSIEYVIERNCELTQ 750

  Fly   392 TVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEI 456
            .....|.|   .:.:|..|    ...|...|...:.:|.:...||::::...|  .||...|...
Mosquito   751 VGGMLDSK---GYGIAMPP----NSPFRTAISGAVLKLQEEGKLHILKTRWWK--EKRGGGSCRD 806

  Fly   457 CPQDLGGTERQLRNGDLMMTYYIMLAGFATALAV------------------------FSTELMF 497
            .......|..:|...::...:.:::.|...|..:                        .::||.|
Mosquito   807 DTSKSSSTANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEEREVSLCSEMASELRF 871

  Fly   498 RYVNSRQEANKWARHGIGRT------PNGQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPP 556
            ....:|.:.......|..||      |...:..||                   |.||:.....|
Mosquito   872 ALKRNRAQPKHAGSGGTLRTASSRASPKDSASEPS-------------------SEHGRFHPLGP 917

  Fly   557 PY 558
            ||
Mosquito   918 PY 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	24/116 (21%)
		Lig_chan	209..458	CDD:459656	70/265 (26%)
KaiR1D	XP_061498559.1	None