Protein Alignment Ir76b and grin2da

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_073787594.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1918
• Species: Danio rerio
• Alignment Length: 689
• Identity: 144/689 - (20%)
• Similarity: 243/689 - (35%)
• Gaps: 230/689 - (33%)

  Fly    67 NRKKPKLREMLDWIGGKHLRIATLEDFPLSYTEVLENGT-------------------RVGHGVS 112
            :|..|.|:.:.|   .:|||:.|||:.|....|..:.||                   .|..|:.
Zfish   440 SRYGPFLKPLDD---SQHLRVVTLEERPFVIVEPADPGTGSCIRDSVPCRLPLNNRSSMVVEGIQ 501

  Fly   113 FQ-------IIDFLK---KKFNFTYEVVVPQDNIIGSPSDFD-RSLIEMVNSSTVDLAAAFIPSL 166
            ..       .||.||   |...|||::.:..:...|...|.. ..::..|.|...|:|...: ::
Zfish   502 SMKHCCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGKNIDGQWNGMVGEVVSKRADMAIGSL-TI 565

  Fly   167 SDQRS-FVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAV---------- 220
            :::|| .|.:|...::.|..:|| .|...:.|.|..|.|:...||:::.|..|:|
Zfish   566 NEERSEVVEFSVPFVETGISVMV-SRSNGTVSPSAFLEPYSPAVWVMMFVMCLSVVAVTVFIFEF 629

  Fly   221 -GPIIYALIILRNRLTGDGQQTPYSLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWIFITI 283
             .|:.|...:...:..|..:   :::|...|.::..:......: :|...:::::...|..|..|
Zfish   630 FSPVGYNRSLQSGKTAGGSK---FTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVI 691

  Fly   284 LTSFYTANLTAFLTLSKFTLPYNTVNDILTKN-KH---------FVSMRGGGVEYAIRTTNESLS 338
            ..:.|||||.||:...::   .:||:.:..|. :|         |.::..|..|..||:...  :
Zfish   692 FLASYTANLAAFMIQEEY---IDTVSGLSDKKFQHPTEQYPPLRFGTVPNGSTEENIRSNYP--N 751

  Fly   339 MLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYV--FVRDRPAINIMLYRDYLYRKTVSFSDEKVH 401
            |...|::||.....|.      ::|.  |.|.:  |:.|...:|.|..:|. ..|.::....||.
Zfish   752 MHQYMVRNNQRGVEDA------IENL--KTGKLDAFIYDAAVLNYMARKDE-GCKVMTIGSGKVF 807

  Fly   402 CP--FAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVE----SGIVKHLSKRNLPSAEICPQD 460
            ..  :.:|    |.|...:..|:...|.||...:.:.::|    |||. |..|..:.|:::...:
Zfish   808 ATTGYGVA----LHKNSRWKRPLDLALLQLVGDDEIDMLERLWLSGIC-HNDKIEVMSSKLDIDN 867

  Fly   461 LGGTERQLRNGDLMMTYYIMLAGFATALAVFSTE-LMFRYVNSRQEANKW-ARHGIGRT------ 517
            :.|            .:|::|.....:|.||:.| |::           | .||.:|||
Zfish   868 MAG------------VFYMLLVAMGLSLLVFAWEHLVY-----------WKLRHCLGRTRGLDFL 909

  Fly   518 ------------------PNG-QSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPP------ 557
                              |.| ||..|..           |        |...|.||||
Zfish   910 LAFSRGMYSCCNFEDETAPGGSQSTLPQY-----------H--------HVSTVPPPPPPHVIST 955

  Fly   558 ---------------------------YQSIFNG----GSH-------------GDPL------- 571
                                       |.::..|    |.|             |.|:
Zfish   956 AVANPPIAMAQQLPQQQQKQHHQQPPVYSALLPGSPPSGGHSAMALGPSNSPILGAPMPCSTFLP 1020

  Fly   572 ---------NRWRRPLANGNALGNGVLLGGDSEGGVRRL 601
                     :||.||.. |:...:||      .||:..|
Zfish  1021 RHDRRLAVVDRWTRPKV-GSEKPSGV------SGGITDL 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	33/139 (24%)
		Lig_chan	209..458	CDD:459656	60/278 (22%)
grin2da	XP_073787594.1	None