Protein Alignment Ir76b and grid2

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001004123.1
• Gene: grid2 / 448841
• ZFINID: ZDB-GENE-040913-1
• Length: 1009
• Species: Danio rerio
• Alignment Length: 686
• Identity: 156/686 - (22%)
• Similarity: 265/686 - (38%)
• Gaps: 145/686 - (21%)

  Fly    26 TNLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETLET---INRKKPKL--REMLDWIGGKHL 85
            |:|::..:||: :|  .:..::..:..|.|....|..|.|   |:.....|  |::.:.:.|..|
Zfish   382 TSLLEFNDNGS-NP--NIHFEILGTNYGEDRGRGVSRLATWDPIHGLNGTLTDRKLENNMRGVVL 443

  Fly    86 RIATLEDFPLSYTEVLEN---GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFD--- 144
            |:.|:.:.|  :..|.||   ..:...|.|..::|.|.....|.||:.|..|:..|| ...|
Zfish   444 RVVTVLEEP--FVMVSENVLGKPKKYQGFSIDVLDALANYLGFKYEIYVAPDHKYGS-QQADGTW 505

  Fly   145 RSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWV 209
            ..||..:.....|:..:.:....::.|.|.::|..:|....:: :::...:......||||:..:
Zfish   506 NGLIGELVFKRADVGLSALTITPERESVVDFTTRYMDYSVGVL-LRKAERTVDMFACLAPFDLSL 569

  Fly   210 WILILVSLLAVGPIIYALIILRNRLTGDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLF 274
            |..|..::|.||.::|.|..|.......|..:..:|.:..|||||:.::||..:.....:||::.
Zfish   570 WACIAGTVLLVGTLVYLLNWLNPPRLPMGSVSSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMM 634

  Fly   275 ATWWIFITILTSFYTANLTAFLTLSKF--------------TLPYNTVNDILTKNKHFVSMRGGG 325
            ..||:|..|:.|.|||||.||||:|:.              .|||.||.|    :..:..:|..|
Zfish   635 GVWWLFALIVISSYTANLAAFLTISRIENSIQSLQDLAKQTDLPYGTVLD----SAVYDQVRSKG 695

  Fly   326 VEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVE--KNG--------YVFVRDRPAIN 380
            :....|  :...|.:.|||           |.|...:|.||  |.|        :.||.|...:.
Zfish   696 MNPFER--DPMYSQMWRMI-----------NRTGGAENNVEESKEGIRKVKYGRFAFVWDAAVLE 747

  Fly   381 IMLYRD---YLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGI 442
            .:...|   .||..:.:.:|.    .:.||.:.            ||....:|...:|.|.::|.
Zfish   748 YVAINDEDCSLYTVSNNVADR----GYGMAMQH------------GSPYRDIFSQRILELQQNGD 796

  Fly   443 VKHLSKRNLPSAEICPQDLGGTERQLRNGDLM------MTYYIMLAGFATALAVFSTELMFRYVN 501
            :..|..:..|....|  ||.......::|..:      ..::::.||...:..:.:.|..
Zfish   797 MDILKLKWWPRDSPC--DLYSPVGTRKSGSALDIHSFAGVFFVLAAGVVLSCLIATVETW----- 854

  Fly   502 SRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLN-------SGHGQLLGASTHGQNVTP----- 554
                   |.|....|.|:.:............|:|       |.|.|.   ||...::||
Zfish   855 -------WTRRKGSRVPSKEDDKEIDLEHLHHRVNSLCTEDESPHKQF---STSSIDLTPLDMDS 909

  Fly   555 -PPPYQSI-----FNGGSH-------GDPLNRWRRPLANGNALG--NGVLLGGDSEGGVRRLING 604
             |...|::     |. .:|       .:.:....|.|:...|.|  .|.:....:.|..|:
Zfish   910 LPAARQALEQISDFR-NTHITTTTFIPEQIQTLSRSLSAKAAAGFAFGAVQDHRTGGPFRQ---- 969

  Fly   605 RDYMVFRNPNGQSQLVPVRSPSAALFQ------YSY 634
                  |.|||.....||::.|:..:|      :||
Zfish   970 ------RAPNGGFFRSPVKTMSSIPYQPTPAPNFSY 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/114 (23%)
		Lig_chan	209..458	CDD:459656	71/275 (26%)
grid2	NP_001004123.1	PBP1_iGluR_delta_2	28..429	CDD:380614	11/49 (22%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	101/402 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	989..1009		3/11 (27%)