Protein Alignment Ir76b and GluRIB

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 134/695 - (19%)
• Similarity: 242/695 - (34%)
• Gaps: 213/695 - (30%)

  Fly    27 NLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIGGKHLRIATLE 91
            ::::|..|..:..|.|...|     ||         |:.:|.|..:||..:::...:...:.|:.
  Fly   456 HVVEMTVNSAMVKVAEWNDD-----AG---------LQPLNAKYVRLRPHVEFEKNRTYIVTTVL 506

  Fly    92 DFP------LSYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSD-----FDR 145
            :.|      :::.|.|....|. .|....:.|.|.|:....||:.:.:|...||...     :|.
  Fly   507 EEPYIMLKQVAFGEKLHGNNRF-EGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDG 570

  Fly   146 SLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVW 210
            .:.|:|... .|:|.|.:...:::...:.:|...:..|..||:.:..:::......:.|....:|
  Fly   571 MVGELVRKE-ADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIW 634

  Fly   211 ILILVSLLAVGPIIYAL---------II------------------LRNR----LTG-------D 237
            :.::.|.:.|..:::.:         ::                  |.|:    :.|       .
  Fly   635 VSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPP 699

  Fly   238 GQQTP--------------------------------YSLGHCAWFVYGALMKQGSTLSPIADST 270
            |..||                                :|:.:..||...|.|:||..|||.:.|.
  Fly   700 GPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSG 764

  Fly   271 RLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDIL--TKNKHFVSMRGGGVEYAIRTT 333
            |:..|:|:.|..||.|.|||||.||||:.:...|.|:..|:.  |:.::...:.|...::..|:
  Fly   765 RIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRS- 828

  Fly   334 NESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDE 398
              .:.:.|:|.:                  |:....:|||   |..:..:.|....:...:...|
  Fly   829 --QIGLHNKMWE------------------YMNSRKHVFV---PTYDEGIKRVRNSKGKYALLVE 870

  Fly   399 KVHCPFAMAKEP--FLKKKRT-------FAYPIGSNLSQLFDPELLHLVESG-IVKHLSKRNLPS 453
            .....:..|:||  .:|..|.       .|.|:||.|....:..:|.|.|:| ::|..:|.....
  Fly   871 SPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEK 935

  Fly   454 AEICPQDLGGTER-QLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARHGIGRT 517
            ||......|.|.. :|...::...:||::.|...::.|...|..||
  Fly   936 AECSTHKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFR------------------- 981

  Fly   518 PNGQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNGGSHGDPLNRWRRPLANGN 582
                                                                  :|..|..::|:
  Fly   982 ------------------------------------------------------SRDSRSASSGS 992

  Fly   583 ALGNGVLLGGDSEGGVRRLINGRDYMVFRNPNGQSQLVPVRSPSA 627
            .:|.|:.|||...||.....||...:      |.|..||...||:
  Fly   993 GMGLGMGLGGGMSGGSLGKANGSMML------GPSSAVPGGMPSS 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	87/445 (20%)
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	7/35 (20%)
		ANF_receptor	55..461	CDD:279440	0/4 (0%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	93/466 (20%)
		Lig_chan	632..967	CDD:278489	74/358 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840