Protein Alignment Ir76b and Grik

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 135/539 - (25%)
• Similarity: 217/539 - (40%)
• Gaps: 112/539 - (20%)

  Fly    34 NGTLSPV--------TELPMDVD-------------ASEAGFDAD--APVETLETINRKKPKLRE 75
            ||...|:        |:..::|.             :.|.||..:  ||..:||      |.:|.
  Fly   350 NGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAHSLE------PDMRS 408

  Fly    76 MLDWIGGKHLRIATLEDFPLSY----TEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNI 136
            :::    |...:.|....|...    :|.|| |.....|...::||.|.||..|:|...:.:||.
  Fly   409 LVN----KSFVVITAISEPYGMLKETSEKLE-GNDQFEGFGIELIDELSKKLGFSYTWRLQEDNK 468

  Fly   137 IG----SPSDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESAS 197
            .|    ...:::..|.|::: |..|:....:...|::.|.|.::...:..|..|:..:..:|...
  Fly   469 YGGIDPKTGEWNGMLREIID-SRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPK 532

  Fly   198 GSGLLAPF--EFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTPY-------------SLGH 247
            ....::||  |.|:|:    .|..:|..|...::  .||:......||             |..:
  Fly   533 LFSFMSPFSGEVWLWL----GLAYMGVSISMFVL--GRLSPAEWDNPYPCIEEPTELENQFSFAN 591

  Fly   248 CAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDIL 312
            |.||..|||::|||.|:|.|.|||.:.|:||.|..||.|.|||||.||||:.....|.|..:| |
  Fly   592 CLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADD-L 655

  Fly   313 TKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFS-------DE----TNDTYNLQNYVE 366
            :|||       |||.|..:....:.:...   ::||..:.       |.    ||......:.||
  Fly   656 SKNK-------GGVNYGAKIGGATFNFFK---ESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVE 710

  Fly   367 KNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFD 431
            .:.|.|:.:...|..:..|.....:..:..|||.: ..||.|.          :|....|||
  Fly   711 NSNYAFLMESTTIEYITERRCTLTQVGALLDEKGY-GIAMRKN----------WPYRDTLSQ--- 761

  Fly   432 PELLHLVESGIVKHL------SKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAV 490
             .:|.:.|.|::..:      .||...:.....:|.|....::.|  |...:.:|  |..:...:
  Fly   762 -AVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISN--LGGVFLVM--GVGSFFGI 821

  Fly   491 FSTEL-MFRYVNSRQEANK 508
            |.:.| |...|..|.:.|:
  Fly   822 FVSLLEMVLGVKERSDENQ 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	27/116 (23%)
		Lig_chan	209..458	CDD:459656	77/278 (28%)
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	8/44 (18%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	107/407 (26%)