DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir76b and Ir84a

DIOPT Version :9

Sequence 1:	NP_649176.1	Gene:	Ir76b / 40198	FlyBaseID:	FBgn0036937	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_649720.2	Gene:	Ir84a / 40891	FlyBaseID:	FBgn0037501	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	102/485 - (21%)
Similarity:	183/485 - (37%)	Gaps:	119/485 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIGGKHLRIATLEDFPLSYTEVLENG 104
            :||.|......|...| |..::.|:.:.||..:|.::::.:....|.|:..:    .:.|:|:||
  Fly   231 LTEKPPGFGDMEYLAD-DKQLQQLDPMQRKTYQLFQLVERMFNLSLAISLTD----KWGELLDNG 290

  Fly   105 TRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRSLIEMVNSSTVDLAAAFIPSLSDQ 169
            :..|                           ::|           .|.|...|.|...|..:.|:
  Fly   291 SWSG---------------------------VMG-----------QVTSREADFAVCPIRFVLDR 317

  Fly   170 RSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRL 234
            :.:|.|| ..|.......:.:.||.|...:....|....||..:|.  |..|..|..|..:|...
  Fly   318 QPYVQYS-AVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQVWWCVLA--LVTGSTILLLFHVRLER 379

  Fly   235 TGDGQQTPYSLGHCAWF-VYGALMKQGSTLSPIAD-----STRLLFATWWIFITILTSFYTANLT 293
            .....:..:|.   .|| :....::||    |..:     |||||.:...||..:|..||.|.:
  Fly   380 MLSNMENRFSF---VWFTMLETYLQQG----PANEIFRLFSTRLLISLSCIFSFMLMQFYGAFI- 436

  Fly   294 AFLTLSKFTLPYNTVNDILTKN-KHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETN- 356
                          |..:|::: :..|:::      |:..:|.::.|.|  |..|:.:|::.:|
  Fly   437 --------------VGSLLSESARSIVNLQ------ALYDSNLAIGMEN--ISYNFPIFTNTSNQ 479

  Fly   357 ---DTY-------------NLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFS-DEKVHCPF 404
               |.|             :||...|:    .::.|.|.:..:  |.:||..:... ||...|..
  Fly   480 LVRDVYVKKICKSGEHNIMSLQQGAER----IIQGRFAFHTAI--DRMYRLLLELQMDEAEFCDL 538

  Fly   405 --AMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTERQ 467
              .|...|:   ......|.||...:.....|||...:|::::..|:.:.....|  .|..|.:
  Fly   539 QEVMFNLPY---DSGSVMPKGSPWREHLAHALLHFRATGLLQYNDKKWMVRRPDC--SLFKTSQ- 597

  Fly   468 LRNGDLMMTYYIMLAGFATALAVFSTELMF 497
               .::.:.::.. |.||.|||:.::.|:|
  Fly   598 ---AEVDLEHFAP-ALFALALAMVASALVF 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	78/380 (21%)
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	91/436 (21%)
		Lig_chan	355..602	CDD:278489	62/293 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462887
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940