Protein Alignment Ir76b and Nmdar1

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 149/705 - (21%)
• Similarity: 240/705 - (34%)
• Gaps: 224/705 - (31%)

  Fly    21 NDSPPTNLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETLETINRK-----------KPKLR 74
            |.:..|..:...:||            |...||:|    |..:....:|           :.|:|
  Fly   345 NITGETGQVAFDDNG------------DRIYAGYD----VINIREQQKKHVVGKFSYDSMRAKMR 393

  Fly    75 EMLD-----WIGGK-----------HLRIATLEDFPLSYTEVLENGTRVG--------------- 108
            ..::     |.|.:           |||:.|:|:.|..|..      |:|
  Fly   394 MRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVR------RMGDDEFRCEPDERPCPL 452

  Fly   109 -------------HGVSFQIIDFLKKKFNFTYEVVVPQDNIIGS------------PSDFDRSLI 148
                         .|....::..|.|:.||||::.:..|...|.            ..::...:.
  Fly   453 FNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIG 517

  Fly   149 EMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILI 213
            |:|| ...|:..|.:....::..::.:|.....:|..|: .::|..|::....|.||...:|||:
  Fly   518 ELVN-ERADMIVAPLTINPERAEYIEFSKPFKYQGITIL-EKKPSRSSTLVSFLQPFSNTLWILV 580

  Fly   214 LVSLLAVGPIIYALIILRNRLTGDG----------QQTPYSLGHCAWFVYGALMKQG-STLSPIA 267
            :||:..|..::|.|    :|.:..|          ::...:|....||.:|.|:..| ...:|.:
  Fly   581 MVSVHVVALVLYLL----DRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRS 641

  Fly   268 DSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK----HFVSMRGGGVEY 328
            .|.|:|...|..|..|:.:.|||||.|||.|.:.....:.:||...:|.    ...:::|..|:.
  Fly   642 FSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDM 706

  Fly   329 AIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNG--YVFVRDRPAINIMLYRDYLYRK 391
            ..|...|..:|...|..||||.......|.        |.|  ..|:.|...:.....:|
  Fly   707 YFRRQVELSNMYRTMEANNYATAEQAIQDV--------KKGKLMAFIWDSSRLEYEASKD----- 758

  Fly   392 TVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSK-------- 448
                      |....|.|.|.:.........||..:......:|...|||.::.|.|
  Fly   759 ----------CELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHV 813

  Fly   449 -RNLPSAEICPQDLGGTERQLRNGDLMMTYYIML-AGFATALAVFSTELMF---------RYVNS 502
             :|....|..|..||     |:|   |...:|:: .|.|..:.:...|:::         |...:
  Fly   814 QQNCELFEKTPNTLG-----LKN---MAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIA 870

  Fly   503 RQEANKW-------------------------ARHGIG---------RTPN-GQSVAPSR-W--- 528
            |..|:||                         :.|..|         |.|. ||.:.|.| |
  Fly   871 RHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRRYPRLGQRLGPERAWPGD 935

  Fly   529 ----LRGWRRLNSGH-GQ---------------LLGASTHGQNVTPP---PPYQS 560
                ||..|....|: ||               :||.:...|:|.||   |.|.|
  Fly   936 AADVLRIRRPYELGNPGQSPKVMAANQPGMPMPMLGKTRPQQSVLPPRYSPGYTS 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/159 (16%)
		Lig_chan	209..458	CDD:459656	65/274 (24%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	13/75 (17%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	95/435 (22%)
		CaM_bdg_C0	854..882	CDD:402271	5/27 (19%)