Protein Alignment Ir76b and GluRIA

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Alignment Length: 564
• Identity: 116/564 - (20%)
• Similarity: 199/564 - (35%)
• Gaps: 164/564 - (29%)

  Fly    27 NLIQMGENGTLSPVTE-------LPM----------DVDASEAGFDADAPVETLETINRKKPKLR 74
            ::::|..|.||..|.|       ||:          ...||...:|.:
  Fly   430 HVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRN----------------- 477

  Fly    75 EMLDWIGGKHLRIAT--LEDFPLSYTEVLENGTRVGH----GVSFQIIDFLKKKFNFTYEVVVPQ 133
                     |..|.:  ||:..||..:.....:.||:    |....:.|.|..:....||:.:.|
  Fly   478 ---------HTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQ 533

  Fly   134 DNIIG-----SPSDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPR 193
            |...|     :|..:|..:.|::... .|:|.:.:...:::...:.:|...:..|..||:.:..:
  Fly   534 DGNYGAENQYAPGGWDGMVGELIRKE-ADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVK 597

  Fly   194 ESASGSGLLAPFEFWVWILILVSLLAVGPIIYAL---------IILRNRLTGDGQQTPYSLG--- 246
            ::......|.|....:||.:::|.:.|..::|.:         |:.|.:.....||.|..:|
  Fly   598 QTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGAT 662

  Fly   247 -------------------HCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANL 292
                               :..|:...|.|:||..::|.:.:.|:..|.||.|..||.|.|||||
  Fly   663 LSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANL 727

  Fly   293 TAFLTLSKFTLPYNTVNDILTK-------------------------NKHFVSMRGGGVEYAIRT 332
            .||||:.:...|..|..|:..:                         ||.:..| .....:::.|
  Fly   728 AAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYM-NANQHHSVHT 791

  Fly   333 TNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSD 397
            .:|.:..: |..:..||:..:...:.|             |..||..:.|        |.....|
  Fly   792 YDEGIRRV-RQSKGKYALLVESPKNEY-------------VNARPPCDTM--------KVGRNID 834

  Fly   398 EKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKR--------NLPSA 454
            .|   .|.:|.            ||||.|.:..:..:|.|.|:|.:..:..:        ||...
  Fly   835 TK---GFGVAT------------PIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQE 884

  Fly   455 EICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFR 498
            ...|.:|     .|.|  :...|||::.|...|:.|...|...|
  Fly   885 TSTPNEL-----SLSN--VAGIYYILIGGLLLAVIVAIMEFFCR 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	88/420 (21%)
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	6/22 (27%)
		ANF_receptor	53..434	CDD:279440	0/3 (0%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	91/466 (20%)
		Lig_chan	612..907	CDD:278489	73/339 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840