Protein Alignment Ir76b and gria4b

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 534
• Identity: 106/534 - (19%)
• Similarity: 197/534 - (36%)
• Gaps: 117/534 - (21%)

  Fly    87 IATLEDFPLSYTEVLEN-----GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRS 146
            :.|:.:.|  |..:.:|     |.....|....:...:.|...|.|::.:..|...|:.....:.
Zfish   419 VTTIMEGP--YVMLKKNWEMYEGNEQYEGYCVDLASEIAKHIGFKYKISIVPDGKYGARDPETKI 481

  Fly   147 LIEMVNS---STVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG-SGLLAPFEF 207
            ...||..   ...::|.|.:.....:...:.:|...:..|..||: ::|::|..| ...|.|..:
Zfish   482 WNGMVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMI-KKPQKSKPGVFSFLDPLAY 545

  Fly   208 WVWILILVSLLAVGPIIYALIILR---------------NRLTGDGQQTPYSLGHCAWFVYGALM 257
            .:|:.|:.:.:.|..:::  ::.|               :.|..|.....:.:.:..||..||.|
Zfish   546 EIWMCIVFAYIGVSVVLF--LVSRFSPYEWHTEEPEEGTDGLPSDQPPNEFGIFNSLWFSLGAFM 608

  Fly   258 KQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLP--------------YNTV 308
            :||..:||.:.|.|::...||.|..|:.|.|||||.||||:.:...|              |.|:
Zfish   609 QQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTDIAYGTL 673

  Fly   309 NDILTK-----------NKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQ 362
            :...||           .|.:..|:........:||.|.::.: |..:..||...:.|.:.|
Zfish   674 DSGSTKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTAEGVARV-RKSKGKYAFLLESTMNEY--- 734

  Fly   363 NYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLS 427
                                             ::::..|...........|....|.|.||.|.
Zfish   735 ---------------------------------TEQRKPCDTMKVGGNLDSKGYGVATPKGSQLR 766

  Fly   428 QLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGG----TERQLRNGDLMMTYYIMLAGFATAL 488
            ...:..:|.|.|.|::..|..:.......|....||    :.:.|...::...:||::.|...|:
Zfish   767 SAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGGEKDKSSQALSLSNVAGVFYILVGGLGLAM 831

  Fly   489 AVFSTELMFRYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLNSGHGQLLGA-STHGQNV 552
            .|...|..::   ||.||.:            ..:..:..:|...||:     :.|: ..:|:.:
Zfish   832 LVALIEFCYK---SRNEAKR------------MKLTFTEAMRNKARLS-----ITGSVGENGRVL 876

  Fly   553 TPPPPYQSIFNGGS 566
            ||..| :::.:|.|
Zfish   877 TPDCP-KAVHSGPS 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	19/112 (17%)
		Lig_chan	209..458	CDD:459656	58/288 (20%)
gria4b	NP_997917.2	Periplasmic_Binding_Protein_type1	28..400	CDD:471960
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	82/415 (20%)
		Lig_chan	546..826	CDD:459656	64/318 (20%)