Protein Alignment Ir76b and Ir8a

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 141/633 - (22%)
• Similarity: 234/633 - (36%)
• Gaps: 149/633 - (23%)

  Fly    23 SPPTNLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDW--IGGKHL 85
            :||...||   :...|||..|...|:.|...:.::...:|            ::..|  :|...|
  Fly   325 APPLPHIQ---DQFQSPVPGLTFAVNISAGYYSSEHEAKT------------DLAAWSSVGEMRL 374

  Fly    86 ------------RIATLEDFPLSYTEVLE---------NGTRVGHGVSFQIIDFLKKKFNFTYEV 129
                        ||.|.|..|.||....|         :|..:..|.....|..|.:|.||.:|:
  Fly   375 LNETISPARRFFRIGTAESIPWSYLRREEGTGELIRDRSGLPIWEGYCIDFIIRLSQKLNFEFEI 439

  Fly   130 VVPQDNIIGSPS---DFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFV-----YYSTTTLDEGEWI 186
            |.|:...:|..:   ::|..:.::|...| |.|.|.:...|::...:     ||..|.:.
  Fly   440 VAPEVGHMGELNELGEWDGVVGDLVRGET-DFAIAALKMYSEREEVIDFLPPYYEQTGIS----- 498

  Fly   187 MVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPII-----YALIILRNRLTGDGQQTPY--- 243
            :.:::|....|....:......||:.|:.:|:....:|     |:....||    :.|..||
  Fly   499 IAIRKPVRRTSLFKFMTVLRLEVWLSIVAALVGTAIMIWFMDKYSPYSSRN----NRQAYPYACR 559

  Fly   244 --SLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLP-- 304
              :|....||...:...||...:|.|.|.|:|.|.:|:|:.::.:.:||||.||||:.:...|
  Fly   560 EFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTPVQ 624

  Fly   305 ------------YNTVNDILTKNKHFVSMRGG-------GVEYAIRTTNE--SLSMLNRMIQNNY 348
                        |..|.|..| :::||:|:..       ..|.|:..:.:  ...:.:..|:..|
  Fly   625 SLEQLARQSRINYTVVKDSDT-HQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQY 688

  Fly   349 -----AVFS-----DETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCP 403
                 |:.|     |......|:..: |...|.|:.|...|...:.|               :|.
  Fly   689 GHILLAINSSQPVADAKEGFANVDAH-ENADYAFIHDSAEIKYEITR---------------NCN 737

  Fly   404 FAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHL-----VESGIVKHLSKRNLPSAEICP--QDL 461
            .....|.|.::....|...||:|.......:|.|     .|....|:.::.|||:   ||  :|.
  Fly   738 LTEVGEVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYWNQSNLPN---CPLSEDQ 799

  Fly   462 GGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEA---------NKWARHGIGRT 517
            .|...:...|..:.|    |.|...|:.....|::  |...:|.|         |..:..| |.:
  Fly   800 EGITLESLGGVFIAT----LFGLVLAMMTLGMEVL--YYKKKQNALEITQVRPVNDSSGSG-GNS 857

  Fly   518 PNGQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQ-SIFNG 564
            ......|.|...:.|      |..:|.|......|:|||.:: :.|.|
  Fly   858 STAPPTATSTTKQAW------HIPVLEAEEKPAKVSPPPSFETATFRG 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	30/137 (22%)
		Lig_chan	209..458	CDD:459656	68/296 (23%)
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	96/429 (22%)