DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir76b and GluRIIE

DIOPT Version :10

Sequence 1:NP_649176.1 Gene:Ir76b / 40198 FlyBaseID:FBgn0036937 Length:636 Species:Drosophila melanogaster
Sequence 2:NP_001036733.1 Gene:GluRIIE / 318623 FlyBaseID:FBgn0051201 Length:897 Species:Drosophila melanogaster


Alignment Length:438 Identity:111/438 - (25%)
Similarity:177/438 - (40%) Gaps:92/438 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 SYTEVLENGTRVGHGVSF--QIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRS------LIEMVN 152
            :|.::..|....|:||..  ::.|  |..||||:   |...|..||   :::|      ::..:.
  Fly   439 TYKQLEGNSQYEGYGVDLIKELAD--KLGFNFTF---VNGGNDYGS---YNKSTNESTGMLREIM 495

  Fly   153 SSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSL 217
            :...|||...:...|::...:.::...::.|..|:.::..:.:......:.||...||..:..|.
  Fly   496 TGRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSF 560

  Fly   218 LAVGPIIYALIILRNRLTGDGQQTPY-------------SLGHCAWFVYGALMKQGSTLSPIADS 269
            |.|....:.|    .||:......||             :||:..||..|||::|||.:.|.|.|
  Fly   561 LGVSLSFFIL----GRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALLQQGSEIGPKALS 621

  Fly   270 TRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTN 334
            ||.:.:.||.|..|:.|.|||||.||||:.|.....|:|:| |..||       .||.|..:.|.
  Fly   622 TRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDD-LADNK-------DGVVYGAKKTG 678

  Fly   335 ESLSMLNRMIQNNYA---VFSDE-----TNDTYNLQNYVEKN-GYVFVRDRPAINIMLYRDYLYR 390
            .:.:......:..|.   .|..|     |.|.....|.|:.| .|.|:.:..:|.....|:...:
  Fly   679 STRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLMESTSIEYNTKRECNLK 743

  Fly   391 KTVSFSDEKVHCPFAMAKE-PFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHL-------- 446
            |.....|||.: ..||.|: |...|               |:..||.|.|.|:::.:        
  Fly   744 KIGDALDEKGY-GIAMRKDWPHRGK---------------FNNALLELQEQGVLEKMKNKWWNEV 792

  Fly   447 ------SKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATAL 488
                  :|.:.|.|  .|.|:...|.         .::::|.|...||
  Fly   793 GTGICATKEDAPDA--TPLDMNNLEG---------VFFVLLVGSCCAL 829

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir76bNP_649176.1 Lig_chan-Glu_bd 83..192 CDD:463166 22/103 (21%)
Lig_chan 209..458 CDD:459656 80/285 (28%)
GluRIIENP_001036733.1 PBP1_iGluR_Kainate 40..402 CDD:380605
PBP2_iGluR_Kainate 419..790 CDD:270432 101/386 (26%)
Lig_chan 551..824 CDD:459656 84/311 (27%)
Blue background indicates that the domain is not in the aligned region.

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