DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir76b and Grik1

DIOPT Version :10

Sequence 1:NP_649176.1 Gene:Ir76b / 40198 FlyBaseID:FBgn0036937 Length:636 Species:Drosophila melanogaster
Sequence 2:NP_001104587.1 Gene:Grik1 / 29559 RGDID:2732 Length:949 Species:Rattus norvegicus


Alignment Length:448 Identity:95/448 - (21%)
Similarity:173/448 - (38%) Gaps:104/448 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 IDFLKKKFN---FTYEVVVPQDNIIGSPSDFD--RSLIEMVNSSTVDLAAAFIPSLSDQRSFVYY 175
            :|.||:..|   |.|:|.:..|...|:.:|..  ..:::.:.....|||.|.:       :..|.
  Rat   480 LDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPL-------TITYV 537

  Fly   176 STTTLDEGEWIMVM------QRPRESASG-SGLLAPFEFWVWILILVSLLAVGPIIYALIILRNR 233
            ....:|..:..|.:      ::|..:..| ...|.|....:|:.:|::.|.|..:::.:.    |
  Rat   538 REKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIA----R 598

  Fly   234 LT-------------GDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILT 285
            .|             .|..:..::|.:..||..||||:|||.|.|.|.|||::...||.|..|:.
  Rat   599 FTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIII 663

  Fly   286 SFYTANLTAFLTLSKFTLPYNTVNDILTKNK-HFVSMRGGGV--------------EYAIRTTNE 335
            |.|||||.||||:.:...|.::.:|:..:.| .:.::|.|..              .:|..::.:
  Rat   664 SSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQ 728

  Fly   336 SLSM-------LNRMIQNNYAVFSDETNDTYNLQ---NYVEKNGYVFVRDRPAINIMLYRDYLYR 390
            ..::       :.|::..:||:..:.|:..|..|   |..:..|.:                   
  Rat   729 QSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLI------------------- 774

  Fly   391 KTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAE 455
                  |.|.:               ....||||.........:|.|.|.|.: |:.|.......
  Rat   775 ------DSKGY---------------GVGTPIGSPYRDKITIAILQLQEEGKL-HMMKEKWWRGN 817

  Fly   456 ICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMF--RYVNSRQEANKWAR 511
            .||::.......|...::...:.::.||...::.|...|.::  |..|..::..|.:|
  Rat   818 GCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKSSR 875

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir76bNP_649176.1 Lig_chan-Glu_bd 83..192 CDD:463166 17/86 (20%)
Lig_chan 209..458 CDD:459656 63/286 (22%)
Grik1NP_001104587.1 PBP1_iGluR_Kainate 38..431 CDD:380605
Periplasmic_Binding_Protein_Type_2 446..815 CDD:473866 84/386 (22%)
Blue background indicates that the domain is not in the aligned region.

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