Protein Alignment Ir76b and GRIN2C

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 119/606 - (19%)
• Similarity: 211/606 - (34%)
• Gaps: 162/606 - (26%)

  Fly    35 GTLSP-----------VTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLD---------- 78
            |.:||           ||....|...|..|:... |...:..:||.  :|.||:.
Human   397 GPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLVQ-PTMVVIALNRH--RLWEMVGRWEHGVLYMK 458

  Fly    79 ---W----------IGGKHLRIATLEDFPLSYTEVLENGT------------RVGH--------- 109
               |          :..:||.:||||:.|....|..:.||            :..|
Human   459 YPVWPRYSASLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDVAP 523

  Fly   110 -------GVSFQIIDFLKKKFNFTYEVVVPQDNIIGS-PSDFDRSLIEMVNSSTVDLAAAFIPSL 166
                   |....|:..|.:...|:|::.:..:...|. .......:|..|.....|:|...: ::
Human   524 YTKLCCKGFCIDILKKLARVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSL-TI 587

  Fly   167 SDQRS-FVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAV---------- 220
            :::|| .|.:|...::.|..:|| .|...:.|.|..|.|:...||:::.|..|.|
Human   588 NEERSEIVDFSVPFVETGISVMV-ARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEY 651

  Fly   221 -GPIIYALIILRNRLTGDGQQTPYSLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWIFITI 283
             .|:.|...:.|.:.:|.   ..:::|...|.::..:......: :|...:::::...|..|..|
Human   652 FSPVSYNQNLTRGKKSGG---PAFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVI 713

  Fly   284 LTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK-------------------------------H 317
            ..:.|||||.||:...::   .:||:.:..|..                               .
Human   714 FLASYTANLAAFMIQEQY---IDTVSGLSDKKSLHLENTGVAWTAFKTFCSDYFQRPQDQYPPFR 775

  Fly   318 FVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTY--NLQNYVEKNGYVFVRDRPAIN 380
            |.::..|..|..||:...  .|...|::.|.....|......  :....|.:....|:.|...:|
Human   776 FGTVPNGSTERNIRSNYR--DMHTHMVKFNQRSVEDALTSLKMGSEAQPVPRKLDAFIYDAAVLN 838

  Fly   381 IMLYRDYLYRKTVSFSDEKVHCP----FAMAKEPFLKKKRTFAYP--IGSNLSQLFDPELLHLVE 439
            .|..:|. ..|.|:....||...    .||.|:...|:....|..  :|...:|..:...|
Human   839 YMAGKDE-GCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWL---- 898

  Fly   440 SGIVKHLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTE-LMFRYVNSR 503
            |||.:: .|..:.|:::...::.|            .:|::|.....||.||:.| |::
Human   899 SGICQN-EKNEVMSSKLDIDNMAG------------VFYMLLVAMGLALLVFAWEHLVY------ 944

  Fly   504 QEANKW-ARHGIGRTPNGQSV 523
                 | .||.:   ||...:
Human   945 -----WKLRHSV---PNSSQL 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	85/434 (20%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156003
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740