Protein Alignment Ir76b and GRIK5

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_011525167.1
• Gene: GRIK5 / 2901
• HGNCID: 4583
• Length: 982
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 117/510 - (22%)
• Similarity: 198/510 - (38%)
• Gaps: 78/510 - (15%)

  Fly    62 TLETINRKKPKLREMLDWIGGKHLRI-ATLEDFPLS---------YTEVLEN------------- 103
            ||..:.:.:...||:..|...:.|.: ||..|..||         .|.:|||
Human   374 TLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALS 438

  Fly   104 GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSP---SDFDRSLIEMVNSSTVDLAAAFIPS 165
            |.....|....::..|.:...|.|.:.:.:|.:.|:|   ..:...:.|::|....|||.|....
Human   439 GNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTI 503

  Fly   166 LSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIIL 230
            .:::...:.:|...:..|..|:..............|.||...||:.:|::.|||..:::    |
Human   504 TAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLF----L 564

  Fly   231 RNRLTGDGQQTP--------------YSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFI 281
            ..||:......|              |:||:..||..|..|:|||.:.|.|.|||.:...||.|.
Human   565 AARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFT 629

  Fly   282 TILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQN 346
            .|:.|.|||||.||||:.:..:|..:.:|:..:.         .:||.......:::.
Human   630 LIIISSYTANLAAFLTVQRMEVPVESADDLADQT---------NIEYGTIHAGSTMTF------- 678

  Fly   347 NYAVFSDETNDTY-NLQNYVE-KNGYVFVRD-RPAINIMLYRDY--LYRKTVSFSDEKVHCPFAM 406
                |.:....|| .:.||:: |...|||:. ...|..:|...|  |...|::....:::|....
Human   679 ----FQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQ 739

  Fly   407 AKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTERQLRNG 471
            .......|......|:||.........:|.|.|:..::.| ||.......||::.....:.|...
Human   740 IGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEIL-KRKWWEGGRCPKEEDHRAKGLGME 803

  Fly   472 DLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARH-------GIG-RTP 518
            ::...:.:::.|...|:.|...|.::....|.:.....|.|       .:| |||
Human   804 NIGGIFIVLICGLIIAVFVAVMEFIWSTRRSAESEETPALHPAACQCSALGPRTP 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	93/398 (23%)
GRIK5	XP_011525167.1	PBP1_iGluR_Kainate_KA1_2	25..399	CDD:107389	6/24 (25%)
		ANF_receptor	42..379	CDD:279440	2/4 (50%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:304360	92/395 (23%)
		Lig_chan	546..816	CDD:278489	71/294 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840