Protein Alignment Ir76b and GRID2

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 122/508 - (24%)
• Similarity: 200/508 - (39%)
• Gaps: 78/508 - (15%)

  Fly    82 GKHLRIATLEDFPLSYTEVLEN---GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDF 143
            |..||:.|:.:.|  :..|.||   ..:...|.|..::|.|.....|.||:.|..|:..|||.:.
Human   468 GVVLRVVTVLEEP--FVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQED 530

  Fly   144 D--RSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFE 206
            .  ..|:..:.....|:..:.:....|:.:.|.::|..:|....:: ::|..::......||||:
Human   531 GTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVL-LRRAEKTVDMFACLAPFD 594

  Fly   207 FWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTR 271
            ..:|..|..::|.||.::|.|..|.......|..|..:|.:..|||||:.::||..:.....:||
Human   595 LSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATR 659

  Fly   272 LLFATWWIFITILTSFYTANLTAFLT-------------LSKFT-LPYNTVNDILTKNKHFVSMR 322
            ::...||:|..|:.|.|||||.||||             |||.| :||.||.|    :..:..:|
Human   660 MMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTEIPYGTVLD----SAVYEHVR 720

  Fly   323 GGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEK---NGYVFVRDRPAINIMLY 384
            ..|:....|  :...|.:.|||..:    :...|:....|..::|   ..|.||.|...:..:..
Human   721 MKGLNPFER--DSMYSQMWRMINRS----NGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAI 779

  Fly   385 RDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKR 449
            .|             ..|.|.........:....|...||....:|...:|.|.::|.:..|..:
Human   780 ND-------------PDCSFYTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQNGDMDILKHK 831

  Fly   450 NLPSAEICPQDL-GGTERQLRNGDLMM-----TYYIMLAGFATALAVFSTELMFRYVNSRQEANK 508
            ..|....|  || ...:.:.:.|.|.:     .:.|:.||...:..:...|..
Human   832 WWPKNGQC--DLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLSCFIAMLETW------------ 882

  Fly   509 WARHGIGRTPNGQSVAPSRWLRGWRRLN-------SGHGQLLGASTHGQNVTP 554
            |.:....|.|:.:...........||:|       |.|.|.   ||...::||
Human   883 WNKRKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDDSPHKQF---STSSIDLTP 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	95/375 (25%)
GRID2	XP_011530195.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155989
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740