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Protein Alignment Ir76b and GRIA4

DIOPT Version :9

Sequence 1:	NP_649176.1	Gene:	Ir76b / 40198	FlyBaseID:	FBgn0036937	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_000820.4	Gene:	GRIA4 / 2893	HGNCID:	4574	Length:	902	Species:	Homo sapiens

Alignment Length:	533	Identity:	115/533 - (21%)
Similarity:	205/533 - (38%)	Gaps:	126/533 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 ATLEDFPLSYTEVLEN-------------GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGS 139
            |.:|:..:..|.::|:             |.....|....:...:.|.....|::.:..|...|:
Human   410 AAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 474

  Fly   140 PSDFDRSLIE-MVNS---STVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG-S 199
             .|.|..:.. ||..   ...::|.|.:.....:...:.:|...:..|..||: ::|::|..| .
Human   475 -RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMI-KKPQKSKPGVF 537

  Fly   200 GLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLT---------GDGQQTP-------YSLGHC 248
            ..|.|..:.:|:.|:.:.:.|..:::    |.:|.:         .||::.|       :.:.:.
Human   538 SFLDPLAYEIWMCIVFAYIGVSVVLF----LVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNS 598

  Fly   249 AWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLP--------- 304
            .||..||.|:||..:||.:.|.|::...||.|..|:.|.|||||.||||:.:...|
Human   599 LWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 663

  Fly   305 -----YNTVNDILTK-----------NKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSD 353
                 |.|::...||           .|.:..||........|||.|.::.: |..:..:|...:
Human   664 QTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV-RKSKGKFAFLLE 727

  Fly   354 ETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTF 418
            .|     :..|:|:        |...:.|        |.....|.|.:               ..
Human   728 ST-----MNEYIEQ--------RKPCDTM--------KVGGNLDSKGY---------------GV 756

  Fly   419 AYPIGSNLSQLFDPELLHLVESGIVKHL-SKRNLPSAEICPQDLGGTER--QLRNGDLMMTYYIM 480
            |.|.||:|....:..:|.|.|:|::..| :|......|..|:|.|..::  .|...::...:||:
Human   757 ATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYIL 821

  Fly   481 LAGFATALAVFSTELMFRYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLNSGHGQLLGA 545
            :.|...|:.|...|..::   ||.||.:            ..:..|..:|...||:     :.|:
Human   822 VGGLGLAMLVALIEFCYK---SRAEAKR------------MKLTFSEAIRNKARLS-----ITGS 866

  Fly   546 -STHGQNVTPPPP 557
             ..:|:.:||..|
Human   867 VGENGRVLTPDCP 879

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.