Protein Alignment Ir76b and Grin2d

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_038951440.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1334
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 128/607 - (21%)
• Similarity: 222/607 - (36%)
• Gaps: 163/607 - (26%)

  Fly    83 KHLRIATLEDFPLSYTEVLE--NGTRVGHGVSFQ------------------------IIDFLKK 121
            :||.:||||:.|....|..:  :||.:...|..:                        .||.||:
  Rat   427 QHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKR 491

  Fly   122 ---KFNFTYEVVVPQDNIIGSPSD-FDRSLIEMVNSSTVDLAAAFIPSLSDQRS-FVYYSTTTLD 181
               ...|:|::.:..:...|...| ....:|..|.....|:|...: :::::|| .|.:|...::
  Rat   492 LAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSL-TINEERSEIVDFSVPFVE 555

  Fly   182 EGEWIMVMQRPRESASGSGLLA-----------PFEFWVWILILVSLLAV-----------GPII 224
            .|..:|| .|...:.|.|..||           |:...||:::.|..|.|           .|:.
  Rat   556 TGISVMV-ARSNGTVSPSAFLAFAWLTPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVG 619

  Fly   225 YALIILRNRLTGDGQQ---TPYSLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWIFITILT 285
            |      ||....|::   :.:::|...|.::..:......: :|...:::::...|..|..|..
  Rat   620 Y------NRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFL 678

  Fly   286 SFYTANLTAFLTLSKFTLPYNTVNDILTKN----------KHFVSMRGGGVEYAIRTTNESLSML 340
            :.|||||.||:...::.   :||:.:..:.          ..|.::..|..|..||:
  Rat   679 ASYTANLAAFMIQEEYV---DTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRS-------- 732

  Fly   341 NRMIQNNYAVFSDETNDTYNLQNYVE------KNGYV--FVRDRPAINIMLYRDYLYRKTVSFSD 397
            |....::|.|       .|| |..||      |.|.:  |:.|...:|.|..:|. ..|.|:...
  Rat   733 NYPDMHSYMV-------RYN-QPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDE-GCKLVTIGS 788

  Fly   398 EKVHCP--FAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVE----SGIVKHLSKRNLPSAEI 456
            .||...  :.:|    |.|...:..||...|.|....:.:.::|    |||. |..|..:.|:::
  Rat   789 GKVFATTGYGIA----LHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGIC-HNDKIEVMSSKL 848

  Fly   457 CPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTE-LMFRYVNSRQEANKW-ARHGIGRTPN 519
            ...::.|            .:|::|.....:|.||:.| |::           | .||.:|
  Rat   849 DIDNMAG------------VFYMLLVAMGLSLLVFAWEHLVY-----------WRLRHCLG---- 886

  Fly   520 GQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFN----------GGSHGDP---- 570
                 |:..:......:.|......|........||||.|.:.:          |.:...|
  Rat   887 -----PTHRMDFLLAFSRGMYSCCSAEAAPPPAKPPPPPQPLPSPAYPAARPPPGPAPFVPRERA 946

  Fly   571 -LNRWRRPLANGNALGNGVLLG 591
             .:||||....|...|..:..|
  Rat   947 AADRWRRAKGTGPPGGAAIADG 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	92/430 (21%)
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	96/443 (22%)
		PHA03307	<1125..>1312	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740