Protein Alignment Ir76b and Grik5

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 133/577 - (23%)
• Similarity: 219/577 - (37%)
• Gaps: 112/577 - (19%)

  Fly    62 TLETINRKKPKLREMLDWIGGKHLRI-ATLEDFPLS---------YTEVLEN------------- 103
            ||..:.:.:...||:..|...:.|.: ||..|..||         .|.:|||
  Rat   374 TLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALS 438

  Fly   104 GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSP---SDFDRSLIEMVNSSTVDLAAAFIPS 165
            |.....|....::..|.:...|.|.:.:.:|.:.|:|   ..:...:.|::|....|||.|....
  Rat   439 GNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTI 503

  Fly   166 LSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIIL 230
            .:::...:.:|...:..|..|:..............|.||...||:.:|::.|||..:::    |
  Rat   504 TAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLF----L 564

  Fly   231 RNRLTGDGQQTP--------------YSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFI 281
            ..||:......|              |:||:..||..|..|:|||.:.|.|.|||.:...||.|.
  Rat   565 AARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFT 629

  Fly   282 TILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQN 346
            .|:.|.|||||.||||:.:..:|..:.:|:..:.         .:||.......:::.
  Rat   630 LIIISSYTANLAAFLTVQRMEVPVESADDLADQT---------NIEYGTIHAGSTMTF------- 678

  Fly   347 NYAVFSDETNDTY-NLQNYVE-KNGYVFVRD-RPAINIMLYRDY--LYRKTVSFSDEKVHCPFAM 406
                |.:....|| .:.||:: |...|||:. ...|..:|...|  |...|::....:::|....
  Rat   679 ----FQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQ 739

  Fly   407 AKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTERQLRNG 471
            .......|......|:||.........:|.|.|:..::.| ||.......||::.....:.|...
  Rat   740 IGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEIL-KRKWWEGGRCPKEEDHRAKGLGME 803

  Fly   472 DLMMTYYIMLAGFATALAVFSTELMFRYVNSR----------QEANKWARHGIG----------R 516
            ::...:.:::.|.  .:|||...:.|.:...|          ||..:..||.:.          |
  Rat   804 NIGGIFVVLICGL--IIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRR 866

  Fly   517 TPNGQSVAPSR---WLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNGGSHGDP 570
            .|.|    |||   .||..|.:...:|:|..|...|             :.|:||.|
  Rat   867 RPGG----PSRALLSLRAVREMRLSNGKLYSAGAGG-------------DAGAHGGP 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	27/134 (20%)
		Lig_chan	209..458	CDD:459656	68/267 (25%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	6/26 (23%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:473866	92/395 (23%)