Protein Alignment Ir76b and glr-6

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_741822.2
• Gene: glr-6 / 180955
• WormBaseID: WBGene00001617
• Length: 844
• Species: Caenorhabditis elegans
• Alignment Length: 465
• Identity: 103/465 - (22%)
• Similarity: 199/465 - (42%)
• Gaps: 71/465 - (15%)

  Fly    85 LRIATLEDFPLSYTEVLENGTRVGH-GVSFQIIDFLKKKFNFTYEVVVPQDNIIG----SPSDFD 144
            |::.::.:.|....:::.:| |:.| |....::|.|.:..:|.|.:.:.:||..|    ...::|
 Worm   411 LKVTSIHEKPYVIEKIMPDG-RIKHEGFCVDLLDKLAEMLHFNYTLKIVKDNKYGERKNGTDEWD 474

  Fly   145 RSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEG-EWIMVMQRPRESASGSGLLAPFEFW 208
            ..:.|::... .|:|.|.|...:.:...:.::...|..| ..:|....|:.|:|.:..|.|....
 Worm   475 GMIGEILRGD-ADMAVAPITVTATRLEVIDFTDPFLQLGISMLMRQPNPKSSSSLTRFLWPLSAS 538

  Fly   209 VWILILVSLLAVGPIIYALIILRNRLTGDGQQT-PYSLGHCAWFVYGALMKQGSTLSPIADSTRL 272
            ||     :..|:..:|.||::....:....:.| .:.:.:..|::...|::.||..:..|.:|||
 Worm   539 VW-----TFSAIATVITALLVTVAAVLSPKESTAEFKIQNSVWYLVCILLRAGSGYNCQAGATRL 598

  Fly   273 LFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKH-FVSMRGGG-VEYAIRTTNE 335
            :.|.||.|..:|.:.||||..|.||:.:.::|:|:..::..:.:: |.|:.||. :::...:..|
 Worm   599 ISAVWWSFTLVLIAQYTANFAALLTVDRKSMPFNSFEELGNQTEYNFGSILGGSTMQFFKYSRIE 663

  Fly   336 SLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKV 400
            :...|...:|:                  .|.:.:|.. :...:|.:|...|::....:..|.:|
 Worm   664 TFRRLWERMQS------------------AEPSAFVGT-NHEGVNRVLNEKYVFLMESATLDYQV 709

  Fly   401 --HCPFAMAKEPFL-KKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHL-------SKRNLPSAE 455
              :|.........| ....:.|.|.||...:....::|.|.|.||:..|       |::...|:|
 Worm   710 TQNCNLTRVGNVVLGSNGYSIALPKGSKWREKLTRQILDLNEKGIILMLKNNWWKKSQQECQSSE 774

  Fly   456 ICPQDLG---GTERQLRNGDLMMTYYIMLA---GFATALAVFS-TELMFRYVNSRQEANKWARHG 513
              |:||.   |.|.       :...:::||   |.....||.. |..:|...|.|.
 Worm   775 --PEDLQTALGAEN-------VYGLFLLLALGSGIGVLCAVLEHTHFIFFEKNKRN--------- 821

  Fly   514 IGRTPNGQSV 523
             |:||..|.:
 Worm   822 -GQTPKLQQM 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	22/112 (20%)
		Lig_chan	209..458	CDD:459656	58/261 (22%)
glr-6	NP_741822.2	PBP1_iGluR_non_NMDA-like	21..394	CDD:380591
		PBP2_iGluR_Kainate	409..764	CDD:270432	82/378 (22%)